Projects funded by the NCN


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224 projects found matching your search criteria :

  1. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  2. Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Marta Dudek

    Politechnika Wrocławska

  3. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  4. True Bioisosteres - Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design

    Call: SONATA BIS 11 , Panel: ST4

    Principal investigator: dr Maura Malińska

    Uniwersytet Warszawski, Wydział Chemii

  5. Combating addiction by targeting α3β4*-nicotinic acetylcholine receptors

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Ákos Nemecz

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

  6. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  7. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Marcin Kołaczkowski

    Uniwersytet Jagielloński, Collegium Medicum

  8. Wood from pine family (Pinaceae) native to Poland as a potent source of pharmacologically active lignans

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Andrzej Patyra

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  9. Advanced coordination materials designed on the basis of functional silsesquioxanes

    Call: OPUS 21 , Panel: ST5

    Principal investigator: dr hab. Beata Dudziec

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  10. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Siedlecki

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  11. AXL receptor signaling in cancer cell growth and drug resistance

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: prof. Marta Miączyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  12. Photodynamics of metal complexes with 2,6-bis(thiazol-2-yl)pyridine derivatives functionalized by aryls and N-donors as ...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Anna Maroń

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  13. Multifunctional character of copper(II) macrocyclic complexes – utilization in atom transfer radical polymerization (ATR...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Adam Gorczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  14. The new methodology for better understanding of ligand-RNA interactions.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr Filip Stefaniak

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  15. Silsesquioxanes as Multifunctional Ligands in Coordination Chemistry and Nano-Building Blocks for Hybrid Materials

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Łukasz John

    Uniwersytet Wrocławski, Wydział Chemii

  16. New therapies of opioid use disorder

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Wojciech Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

  17. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  18. Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  19. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  20. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Przemysław Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  21. Investigation into the mechanism of regulation of nicotinic acetylcholine receptors

    Call: POLS , Panel: NZ3

    Principal investigator: dr Ákos Nemecz

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

  22. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  23. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Alicja Gawalska

    Uniwersytet Jagielloński, Collegium Medicum

  24. Interconversions of supramolecular architectures based on Schiff base ligands and transition metal ions as potential pro...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Martyna Szymańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  25. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: Katarzyna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Role of the Intersubunit and Interdomain Interactions in the GABAA Receptor Modulation by Protons.

    Call: ETIUDA 8 , Panel: NZ1

    Principal investigator: Michał Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  28. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  29. Do potential new MRGPRX2 ligands induce mastocytes degranulation in human?

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Grzegorz Porębski

    Uniwersytet Jagielloński, Collegium Medicum

  30. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  31. MXO2-ISOMER: in search of colour-changing photoswitchable materials based on 4th-row transition-metal complexes with sim...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Jarzembska

    Uniwersytet Warszawski, Wydział Chemii

  32. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Karaś

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  33. Analysis of the conformations of organic compounds in macromolecular structures

    Call: PRELUDIUM 18 , Panel: ST6

    Principal investigator: Joanna Macnar

    Uniwersytet Warszawski, Wydział Chemii

  34. Histamine H3/H4 receptors as the attractive target for the search of biologically active substances

    Call: MAESTRO 1 , Panel: NZ4

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  35. In search of new metalloporphyrinoid catalysts for functionalization of C(sp3)-H bonds

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Karolina Hurej

    Uniwersytet Wrocławski, Wydział Chemii

  36. Bioconjugates labeled with alpha- and beta-particle emitting radionuclides as potential radiopharmaceuticals in Targeted...

    Call: SONATA BIS 9 , Panel: ST4

    Principal investigator: dr hab. Marek Pruszyński

    Instytut Chemii i Techniki Jądrowej

  37. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  38. Binding isotope effects as new, unique tool for studies of receptor - ligand interactions

    Call: MAESTRO 1 , Panel: ST4

    Principal investigator: prof. Piotr Paneth

    POLITECHNIKA ŁÓDZKA

  39. Study on the structure related dielectric properties and molecular dynamics of poly(dimethylsiloxane) crosslinked by met...

    Call: PRELUDIUM 17 , Panel: ST3

    Principal investigator: Angelika Wrzesińska

    Politechnika Łódzka, Wydział Chemiczny

  40. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Marcin Drop

    Uniwersytet Jagielloński, Collegium Medicum

  41. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  42. Synteza nowych funkcjonalnych układów metalosupramolekularnych na bazie ligandów ambidentnych i jonów metali d elektrono...

    Call: ETIUDA 7 , Panel: ST4

    Principal investigator: Anna Walczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  43. Development of new and more efficient treatment against mesothelioma utilizing oncolytic adenovirus armed with ICOS liga...

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny

  44. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr hab. Artur Wnorowski

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  47. Synthesis and physicochemical properties of novel functional metal-organic compounds based on hypophosphite ligands

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Mirosław Mączka

    Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego Polskiej Akademii Nauk

  48. Epigenomic, immunogenetic and proteomic strategies for identification of NK cell determinants of prognostic value for pa...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: prof. Katarzyna Bogunia-Kubik

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  49. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr Sabina Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny