Projects funded by the NCN

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173 projects found matching your search criteria :

  1. FA-PROTACs - Design and Synthesis of Compounds Based on Folic Acid for Degradation of Enzyme Involved in Folate Metaboli...

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Mateusz Daśko

    Politechnika Gdańska

  2. Enzymatic preparation of new dehydrogenated pentacyclic triterpenes of pharmacological importance

    Call: SONATA BIS 14 , Panel: ST4

    Principal investigator: dr Agnieszka Maria Wojtkiewicz

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  3. Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Jan Marian Suski

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  4. EGR1 Protein: A Key Factor in Cellular Homeostasis?

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Marta Leśniczak-Staszak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  5. The two are better than one - biferrocenyl ROS generators as intelligent anticancer agents

    Call: OPUS 27 , Panel: ST5

    Principal investigator: prof. Konrad Maciej Kowalski

    Uniwersytet Łódzki

  6. Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Damian Nestor Plażuk

    Uniwersytet Łódzki

  7. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  8. Tumor viscoelasticity as a central player in glioblastoma treatment - towards mechanopharmacology

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Pogoda

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

  9. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Danuta Dudzik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  10. Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Witold Szaflarski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  11. Design and microfluidic synthesis of hybrid nanocarriers stabilized by novel sugar surfactants as a potential anticancer...

    Call: SONATA BIS 13 , Panel: ST4

    Principal investigator: dr hab. Urszula Jolanta Bazylińska

    Politechnika Wrocławska

  12. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  13. Three to tango - biomaterials with therapeutic and regenerative multifunctionality

    Call: SONATA BIS 13 , Panel: ST11

    Principal investigator: dr Marzena Krystyna Fandzloch

    Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

  14. Compounds modulating function of telomeric proteins TRF1 and TRF2

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Maciej Wojciech Bagiński

    Politechnika Gdańska, Wydział Chemiczny

  15. In vitro anticancer screening of triterpene saponins isolated from beetroot (Beta vulgaris L.) by countercurrent chromat...

    Call: PRELUDIUM 22 , Panel: NZ9

    Principal investigator: Anna Maria Tekieli

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  16. Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Błażej Rubiś

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  17. Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Ryszard Józef Ostaszewski

    Instytut Chemii Organicznej Polska Akademia Nauk

  18. Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

    Call: OPUS 25 , Panel: NZ6

    Principal investigator: dr hab. Angelika Muchowicz

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  19. Preparation and investigation of the biologically active systems with potential anticancer activity, containing P,N-; N,...

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Monika Richert

    Uniwersytet Mikołaja Kopernika w Toruniu

  20. From simple alkaloids to potentially anticancer Ir(III) and Ru(II) complexes supported by the magnetic nanoparticles.

    Call: PRELUDIUM 22 , Panel: ST4

    Principal investigator: Daria Bogumiła Wojtala

    Uniwersytet Wrocławski, Wydział Chemii

  21. Design, Synthesis and Characterization of Functionalized 1,2,4-Trioxanes/Trioxepanes for Antimalarial and Anticancer Use

    Call: SONATINA 7 , Panel: NZ7

    Principal investigator: dr Mohit Kumar Tiwari

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  22. CHIRAL RHENIUM AND RHODIUM COMPLEXES OF ANTICANCER AND ANTIBACTERIAL ACTIVITY: SYNTHESIS, ACTIVITY, AND PHYSICOCHEMICAL ...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Jan Czesław Dobrowolski

    Narodowy Instytut Leków

  23. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  24. Exploring the anticancer, antibacterial and antifungal potential and underlying mechanism of action of plants used in Po...

    Call: SONATA 18 , Panel: NZ9

    Principal investigator: dr Kamila Jadwiga Rachwał

    Uniwersytet Przyrodniczy w Lublinie

  25. Targeted drug delivery systems - synthesis and functionalization of nanocarriers

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Krzysztof Szczepanowicz

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  26. Fungal bioactive substances with targeted pro-health potential - the role ofinteractions, bioavailability and bioavailab...

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Michał Świeca

    Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

  27. Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Hanna Jurata Mazur-Marzec

    Uniwersytet Gdański, Wydział Chemii

  28. Pancreatic cancer oxygenation as a prognostic marker during anticancer therapy

    Call: OPUS 23 , Panel: NZ5

    Principal investigator: dr Martyna Krzykawska-Serda

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  29. Design, synthesis and in vitro and in vivo studies of anticancer potential of phosphonic and phosphinic analogs of sulfo...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Tadeusz Marek Gajda

    Politechnika Łódzka, Wydział Chemiczny

  30. Identification of anticancer phytochemicals of dandelion root (Taraxaci radix) based on metabolomics and bioassay-guided...

    Call: PRELUDIUM 21 , Panel: NZ9

    Principal investigator: Sylwia Irena Pawelec

    Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

  31. Enzyme Responsive Nanoscale Supramolecular Capsules with Application in Anticancer Drug Delivery

    Call: POLONEZ BIS 2 , Panel: ST4

    Principal investigator: dr Venkateswarulu Mangili

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  32. Synthesis, structure analysis, anticancer and antimicrobial activity of new derivatives of salinomycin

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr hab. Adam Włodzimierz Huczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  33. Bioresorbable, electrospun nonwoven as a multi-drug delivery system for a combination glioblastoma therapy

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Monika Anna Musiał-Kulik

    Centrum Materiałów Polimerowych i Węglowych PAN

  34. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  35. Heterocyclization of benzenoid ansamycins core as useful strategy for designing anticancer agents

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Natalia Anna Skrzypczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  36. Anticancer activity of novel derivatives of 9,10-Anthraquinone Dithiocarbamates

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Natalia Anna Maciejewska

    Politechnika Gdańska

  37. Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: dr Joanna Elżbieta Kałafut

    Uniwersytet Medyczny w Lublinie

  38. Switchable with visible light cisplatin analogs and complexes of selected transition metals - photochemical and anticanc...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Krzysztof Szczubiałka

    Uniwersytet Jagielloński, Wydział Chemii

  39. Mitochondria-targeting conjugates as a new anticancer agents

    Call: OPUS 21 , Panel: ST4

    Principal investigator: prof. Adam Włodzimierz Huczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  40. Development of new implantable drug forms, biodegradable nanofibers containing selected betulin derivatives in order to ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Janusz Edward Kasperczyk

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

  41. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Weronika Paulina Kotkowiak

    Instytut Chemii Bioorganicznej PAN

  42. Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

    Call: SONATINA 5 , Panel: NZ3

    Principal investigator: dr Karolina Anna Staniak

    Politechnika Warszawska, Wydział Chemiczny

  43. Preparation and evaluation of biological activity of new biotinylated hop flavonoid analogues.

    Call: SONATA 16 , Panel: NZ9

    Principal investigator: dr hab. Monika Stompor-Gorący

    Uniwersytet Rzeszowski

  44. Effects of receptor action of L- and D-Lactate on cervical cancer cells. Lactate modulation of cell DNA repair response ...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Waldemar Wagner

    Instytut Biologii Medycznej PAN

  45. The use of iodoquinolines for biostimulation and biofortification of selected vegetables in iodine and investigation of ...

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr hab. Aneta Agnieszka Koronowicz

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

  46. Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny

  47. Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr hab. Janusz Marcin Dąbrowski

    Uniwersytet Jagielloński, Wydział Chemii

  48. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  49. Tyrosine-modified polyethylenimine polymers as a promising vectors for siRNA delivery in synergistic cancer immunotherap...

    Call: PRELUDIUM 19 , Panel: NZ5

    Principal investigator: Małgorzata Kubczak

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  50. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

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