Projects funded by the NCN
Evaluation of anticancer activity of new pyridine derivatives perturbing mitotic spindle formation
2016/23/N/NZ7/02599
Keywords:
kinesins inhibitors cytotoxicity cancer diseases
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
- NZ7_15: Toxicology
- NZ3_1: Cell biology
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim
woj. zachodniopomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 12 - announced on 2016-09-15
Amount awarded: 149 400 PLN
Project start date (Y-m-d): 2017-07-13
Project end date (Y-m-d): 2021-05-12
Project duration:: 46 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (2)
- Synthesis and anticancer activity of mitotic-specific 3,4-dihydropyridine-2(1H)-thionesAuthors:Magdalena Perużyńska, Aleksandra Borzyszkowska-Ledwig, Jacek G. Sośnicki, Łukasz Struk, Tomasz J. Idzik, Gabriela Maciejewska, Łukasz Skalski, Katarzyna Piotrowska, Paweł Łukasik, Marek Droździk, Mateusz KurzawskiAcademic press:International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2462), Wydawca: MDPIStatus:PublishedDOI:10.3390/ - link to the publication
- Synteza i aktywność biologiczna nowych pochodnych pirydyno-2-tionu. Wstępne wyniki badań antyproliferacyjnych wobec komórek czerniaka oraz nowotworu piersi.Authors:Aleksandra Borzyszkowska, Jacek G. Sośnicki, Łukasz Struk, Magdalena PerużyńskaConference:III Szczecińskie Sympozjum Młodych Chemików (rok: 2018, ), Wydawca: Wydawnictwo Uczelniane Zachodniopomorskiego Uniwersytetu TechnologicznegoData:konferencja 08.05.2018Status:Published
- Synthesis and biological activity of the new derivatives of pyridine-2tione. Initial results of antiproliferationh tests for human breast adenocarcinoma and human malignant melanoma.Authors:Borzyszkowska-Ledwig Aleksandra, Struk Łukasz, Idzik Tomasz J., Perużyńska Magdalena, Droździk Marek, Sośnicki Jacek G..Conference:21st JCF Frühjahrssymposium and 2nd European Young Chemists' Meeting (rok: 2019, ), Wydawca: Jung Chemiker Forum Bremen and OldenburgData:konferencja 20-23.03.2019Status:Published