Evaluation of endoplasmic reticulum stress control by endogenous lipids in the c

Evaluation of endoplasmic reticulum stress control by endogenous lipids in the context of its anticancer therapeutic potential

2019/33/B/NZ5/03034

Keywords

Descriptors

NZ1_001: Biologia molekularna
NZ5_003: Patogeneza chorób człowieka
NZ3_007: Przekaźnictwo sygnału

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Dariusz Maciej Pytel

Number of co-investigators in the project: 3

Call

OPUS 17 – announced on 2019-03-15

Amount awarded: 1 540 000 PLN
Project start date: 2020-05-04
Project end date: 2025-05-03
Project duration: 60 months (the same as in the proposal)
Project status: Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function

Authors:
Paramita Chakraborty, Rasesh Y. Parikh, Seungho Choi, Danh Tran, Monika Gooz, Zachariah T. Hedley, Do-Sung Kim, Dariusz Pytel, Inhong Kang, Satish N. Nadig, Gyda C. Beeson, Lauren Ball, Meenal Mehrotra, Hongjun Wang, Stefano Berto, Viswanathan Palanisamy, Hong Li , Shilpak Chatterjee , Paulo C. Rodriguez, Eduardo N. Maldonado, J. Alan Diehl, Vamsi K. Gangaraju, Shikhar Mehrotra

Academic press:
Cancer Research (year: 2022, volume: 82(10):1969-1990, pages: 15342), Publisher: AACR Journals

Status:
Published

DOI:
10.1158/0008-5472.CAN-21-3155 – link to the publication
The Structure, Activation and Signaling of IRE1 and Its Role in Determining Cell Fate

Authors:
Natalia Siwecka, Wioletta Rozpedek-Kaminska, Adam Wawrzynkiewicz, Dariusz Pytel, J. Alan Diehl, Ireneusz Majsterek

Academic press:
Biomedicines (year: 2021, volume: 9, 156, pages: 46051), Publisher: MDPI

Status:
Published

DOI:
10.3390/biomedicines9020156 – link to the publication

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