Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Identification of the mechanism of sensitization of human ovarian cancer cells to anticancer drugs by the DNA double strand breaks inhibitors

2016/23/N/NZ7/02023

Keywords:

ovarian cancer sensitization NHEJ HRR DNA repair inhibitors

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Anna Macieja 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 148 800 PLN

Project start date (Y-m-d): 2017-10-12

Project end date (Y-m-d): 2021-10-11

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. DNA Double-Strand Break Repair Inhibitors: YU238259, A12B4C3 and DDRI-18 Overcome the Cisplatin Resistance in Human Ovarian Cancer Cells, but Not under Hypoxia Conditions
    Authors:
    Anna Macieja, Izabela Gulbas, Tomasz Popławski
    Academic press:
    Current Issues in Molecular Biology (rok: 2023, tom: 45(10), strony: 7915-7932), Wydawca: MDPI (Multidisciplinary Digital Publishing Institute)
    Status:
    Published
    DOI:
    10.3390/cimb45100500 - link to the publication