From simple alkaloids to potentially anticancer Ir(III) and Ru(II) complexes supported by the magnetic nanoparticles.
2023/49/N/ST4/00337
Keywords
Descriptors
- ST4_14: Chemia nieorganiczna
- ST5_14: Chemia biologiczna
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Uniwersytet Wrocławski, Wydział Chemii
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 22 – announced on 2023-03-16
- Amount awarded
- 209 800 PLN
- Project start date
- 2024-01-12
- Project end date
- 2027-01-11
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Half-Sandwich Organometallic Ir(III) and Ru(II) Compounds and their Interactions with Biomolecules
- Authors:
- Sandra Kozieł, Daria Wojtala, Magdalena Szmitka, Monika Lesiów, Aleksandra Ziółkowska, Jacek Sawka, Edgar Del Carpio, Debbie C. Crans, Urszula K. Komarnicka
- Academic press:
- ChemPlusChem (year: 2025, volume: 90, pages: e202400621, 1-23), Publisher: Wiley-VCH GmbH
- Status:
- Published
- DOI:
- 10.1002/cplu.202400621 – link to the publication
-
Bilosomal Encapsulation of Binuclear Phosphino Ru(II)–Cu(II) Compounds Enhances Their Selectivity and Activity toward Lung and Prostate Cancers
- Authors:
- Sandra Kozieł, Daria Wojtala, Agata Barzowska-Gogola, Barbara Pucelik, Ewelina Waglewska, Miłosz Siczek, Maciej Witwicki, Alessandro Niorettini, Agnieszka Kyzioł, Magdalena Malik, Urszula Bazylińska, Ewa Błaszczak, Urszula K. Komarnicka
- Academic press:
- Journal of Medicinal Chemistry (year: 2025, volume: 68, pages: 14442-14464), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/acs.jmedchem.5c00486 – link to the publication