Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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STING protein activation combined with anti-vascular agent as a novel strategy for anticancer therapy

2018/31/B/NZ5/01825

Keywords:

tumor microenvironment,cancer immunotherapy antivascular therapy

Descriptors:

  • NZ5_7:
  • NZ4_12:
  • NZ6_1:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ryszard Smolarczyk 

Number of co-investigators in the project: 6

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 784 160 PLN

Project start date (Y-m-d): 2019-06-28

Project end date (Y-m-d): 2023-06-27

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. The Proper Administration Sequence of Radiotherapy and Anti-Vascular Agent—DMXAA Is Essential to Inhibit the Growth of Melanoma Tumors
    Authors:
    Alina Drzyzga, Tomasz Cichoń, Justyna Czapla, Magdalena Jarosz-Biej, Ewelina Pilny, Sybilla Matuszczak, Piotr Wojcieszek, Zbigniew Urbaś, Ryszard Smolarczyk
    Academic press:
    Cancers (rok: 2021, tom: 13, strony: 3924), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13163924 - link to the publication
  2. Prognostic Significance of STING Immunoexpression in Relation to HPV16 Infection in Patients with Squamous Cell Carcinomas of Oral Cavity and Oropharynx
    Authors:
    Beata Biesaga, Ryszard Smolarczyk, Anna Mucha-Małecka, Justyna Czapla, Janusz Ryś, Krzysztof Małecki
    Academic press:
    Biomedicines (rok: 2022, tom: 10(10), strony: 2538), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines10102538 - link to the publication
  3. Vascular disrupting agents in cancer therapy
    Authors:
    Smolarczyk R, Czapla J, Jarosz-Biej M, Czerwinski K, Cichoń T
    Academic press:
    Eur J Pharmacol (rok: 2021, tom: 891, strony: 173692), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2020.173692 - link to the publication

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