Projects funded by the NCN
Novel, chemometrically assisted, metabolic based research strategy in anticancer drug development on the example of benzothiohydrazonate derivatives
2011/01/N/NZ1/00214
Keywords:
anticancer drugs metabolism DNA mass spectroscopy QSAR
Descriptors:
- NZ1_2: Biochemistry
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Gdański Uniwersytet Medyczny, Wydział Faramcautyczny z Oddziałem Medycyny Laboratoryjnej
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 1 - announced on 2011-03-15
Amount awarded: 99 450 PLN
Project start date (Y-m-d): 2011-12-27
Project end date (Y-m-d): 2014-12-26
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Termostat blokowy/inkubator reakcji enzymatycznych (5 000 PLN)
- Komputer stacjonarny (4 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Mass Spectrometry Based Identification of Geometric Isomers during Metabolic Stability Study of a New Cytotoxic Sulfonamide Derivatives Supported by Quantitative Structure-Retention RelationshipsAuthors:Mariusz Belka, Weronika Hewelt-Belka, Jarosław Sławiński, Tomasz BączekAcademic press:PLOS ONE (rok: 2014, tom: 9(6), strony: 14 stron), Wydawca: PLOSStatus:PublishedDOI:10.1371/journal.pone.0098096 - link to the publication
- Antitumor Activity of Novel Benzensulfonamide Derivatives in View of their Physiochemical Properties Searched by Principal Component AnalysisAuthors:M. Belka, J. Slawinski, L. Konieczna, P. Kawczak, T. Ciesielski, T. BaczekAcademic press:Medicinal Chemistry (rok: 2013, tom: 9(4), strony: 517-525), Wydawca: Bentham Science PublishersStatus:PublishedDOI:10.2174/1573406411309040005 - link to the publication