Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Molecular and physiological mechanisms of vanadium influence on the uptake of iodates and iodosalicylates by lettuce and its anticancer effect tested on human cell lines.

2017/25/B/NZ9/00312

Keywords:

functional food vanadium iodine iodine salicylates cancer cells

Descriptors:

  • NZ9_4: Horticulture

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Sylwester Smoleń 

Number of co-investigators in the project: 13

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 209 000 PLN

Project start date (Y-m-d): 2018-01-12

Project end date (Y-m-d): 2023-01-11

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Cytometr przepływowy.
  2. System pomiarowy HPLC wraz detektorem masowym typu pojedynczy quadrupol (LC/MS) (345 000 PLN)
  3. Wyparka obrotowa (15 000 PLN)
  4. Podstawowe zestawy/system do uprawy roślin w hydroponicznym systemie CKP w szklarni - modyfikacja/rozbudowa (10 szt.) (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (2)
  1. Anti- and pro-oxidant potential of lettuce (Lactuca sativa L.) biofortified with iodine by KIO3, 5-iodoand 3,5-diiodosalicylic acid in human gastrointestinal cancer cell lines
    Authors:
    Sularz O., Koronowicz A., Smoleń S., Kowalska I., Skoczylas Ł., Liszka-Skoczylas M., Tabaszewska M., Pitala J
    Academic press:
    RSC Advances (rok: 2021, tom: 11, strony: 27547), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d1ra04679a - link to the publication
  2. Effectiveness of enriching lettuce with iodine using 5-iodosalicylic and 3,5-diiodosalicylic acids and the chemical composition of plants depending on the type of soil in a pot experiment
    Authors:
    Smoleń, S., Kowalska, I., Skoczylas, Ł., Tabaszewska, M., Pitala, J., Mrożek, J., Kováčik, P
    Academic press:
    Food Chemistry (rok: 2022, tom: 382, strony: 132347), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodchem.2022.132347 - link to the publication
  3. Molecular Effects of Iodine-Biofortified Lettuce in Human Gastrointestinal Cancer Cells
    Authors:
    Sularz O, Koronowicz A., Boycott C., Smoleń S., Stefanska B.
    Academic press:
    Nutrients (rok: 2022, tom: 14, strony: 4287), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu14204287 - link to the publication
  4. Chemical composition of lettuce (Lactuca sativa L.) biofortified with iodine by KIO3, 5-iodo-, and 3.5-diiodosalicylic acid in a hydroponic cultivation
    Authors:
    Sularz, O., Smoleń, S., Koronowicz, A., Kowalska, I., Leszczyńska, T
    Academic press:
    Agronomy (rok: 2020, tom: 10, 7, strony: 1022), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/agronomy10071022 - link to the publication
  5. Selected aspects of iodate and iodosalicylate metabolism in lettuce including the activity of vanadium dependent haloperoxidases as affected by exogenous vanadium
    Authors:
    Smoleń S., Kowalska I., Halka M., Ledwożyw-Smoleń I., Grzanka M., Skoczylas Ł., Czernicka M., Pitala J.
    Academic press:
    Agronomy (rok: 2020, tom: 10, strony: 45312), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/agronomy10010001 - link to the publication
  6. New aspects of uptake and metabolism of non-organic and organic iodine compounds — the role of vanadium and plant-derived thyroid hormone analogs in lettuce.
    Authors:
    Smoleń S., Czernicka M., Kowalska I., Kęska K., Halka M., Grzebelus D., Grzanka M., Skoczylas Ł., Pitala J., Koronowicz A., Kováčik P.
    Academic press:
    Frontiers in Plant Science (rok: 2021, tom: 12, strony: 608), Wydawca: Frontiers Editorial Office
    Status:
    Published
    DOI:
    10.3389/fpls.2021.653168 - link to the publication
  1. Funkcja wanadu w procesie wzbogacania roślin w jod.
    Authors:
    Smoleń S., Kowalska I., Halka M., Grzanka M., Sady W
    Conference:
    Life Science Open Space 2018 (rok: 2018, ), Wydawca: Klaster LifeScience Kraków Foundation
    Data:
    konferencja 11 października
    Status:
    Published
  2. Aktywność przeciwnowotworowa roślin wzbogaconych w mineralne i organiczne związki jodu. Biofortyfikacja jako Agrojodoprofilaktka.
    Authors:
    Smoleń S.
    Conference:
    Life Science Open Space (rok: 2019, ), Wydawca: Klaster LifeScience Kraków Foundation
    Data:
    konferencja 43795
    Status:
    Published

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