Inteligent oligosilsesquioxane nanoconjugates of anticancer drugs with targeting

Inteligent oligosilsesquioxane nanoconjugates of anticancer drugs with targeting moieties.

2016/21/N/ST5/03360

Keywords

Descriptors

ST5_10: Nanomateriały: nanocząstki, nanorurki

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Centrum Badań Molekularnych i Makromolekularnych PAN

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Kinga Piórecka

Number of co-investigators in the project: 2

Call

PRELUDIUM 11 – announced on 2016-03-15

Amount awarded: 99 960 PLN
Project start date: 2017-03-08
Project end date: 2020-09-07
Project duration: 42 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)32, as a Complexing Nanocarrier for Doxorubicin and Daunorubicin

Authors:
Kinga Piorecka, Anna Janaszewska, Marta Majkowska, Monika Marcinkowska, Jan Kurjata, Slawomir Kazmierski, Ewa Radzikowska-Cieciura, Bartlomiej Kost, Przemyslaw Sowinski, Barbara Klajnert-Maculewicz, Wlodzimierz A. Stanczyk

Academic press:
Materials (year: 2020, volume: 13, pages: 5512), Publisher: MDPI

Status:
Published

DOI:
10.3390/ma13235512 – link to the publication
Synthetic routes to nanoconjugates of anthracyclines

Authors:
Kinga Piorecka, David Smith, Jan Kurjata, Maciej Stanczyk, Włodzimierz A. Stanczyk

Academic press:
Bioorganic Chemistry (year: 2020, volume: 96, pages: 103617), Publisher: elsevier

Status:
Published

DOI:
10.1016/j.bioorg.2020.103617 – link to the publication
Novel Polyhedral Silsesquioxanes [POSS(OH)32] as Anthracycline Nanocarriers—Potential Anticancer Prodrugs

Authors:
Kinga Piorecka, Jan Kurjata, Wlodzimierz A. Stanczyk

Academic press:
Molecules (year: 2021, volume: 26, pages: 47), Publisher: MDPI

Status:
Published

DOI:
10.3390/molecules26010047 – link to the publication
Reasons for enhanced activity of doxorubicin on co-delivery with octa(3-aminopropyl)silsesquioxane

Authors:
Kinga Piorecka, Jan Kurjata, Irena Bak-Sypien, Marek Cypryk, Urszula Steinke, Wlodzimierz A. Stanczyk

Academic press:
RSC Advances (year: 2020, volume: 10, pages: 15579-15585), Publisher: ROYAL SOCIETY OF CHEMISTRY

Status:
Published

DOI:
10.1039/d0ra01319f – link to the publication
Synthetic routes to nanomaterials containing anthracyclines: noncovalent systems

Authors:
Kinga Piorecka, Jan Kurjata, Maciej Stanczyk and Włodzimierz A. Stanczyk

Academic press:
Biomaterials Science (year: 2018, volume: 6, pages: 2552-2565), Publisher: ROYAL SOCIETY OF CHEMISTRY

Status:
Published

DOI:
10.1039/C8BM00739J – link to the publication

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