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Information of the project and the call

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Inteligent oligosilsesquioxane nanoconjugates of anticancer drugs with targeting moieties.

2016/21/N/ST5/03360

Keywords:

silsesquioxanes nanoconjugates anthracyclines

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Kinga Piórecka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 99 960 PLN

Project start date (Y-m-d): 2017-03-08

Project end date (Y-m-d): 2020-09-07

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)32, as a Complexing Nanocarrier for Doxorubicin and Daunorubicin
    Authors:
    Kinga Piorecka, Anna Janaszewska, Marta Majkowska, Monika Marcinkowska, Jan Kurjata, Slawomir Kazmierski, Ewa Radzikowska-Cieciura, Bartlomiej Kost, Przemyslaw Sowinski, Barbara Klajnert-Maculewicz, Wlodzimierz A. Stanczyk
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 5512), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13235512 - link to the publication
  2. Novel Polyhedral Silsesquioxanes [POSS(OH)32] as Anthracycline Nanocarriers—Potential Anticancer Prodrugs
    Authors:
    Kinga Piorecka, Jan Kurjata, Wlodzimierz A. Stanczyk
    Academic press:
    Molecules (rok: 2021, tom: 26, strony: 47), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26010047 - link to the publication
  3. Reasons for enhanced activity of doxorubicin on co-delivery with octa(3-aminopropyl)silsesquioxane
    Authors:
    Kinga Piorecka, Jan Kurjata, Irena Bak-Sypien, Marek Cypryk, Urszula Steinke, Wlodzimierz A. Stanczyk
    Academic press:
    RSC Advances (rok: 2020, tom: 10, strony: 15579-15585), Wydawca: ROYAL SOCIETY OF CHEMISTRY
    Status:
    Published
    DOI:
    10.1039/d0ra01319f - link to the publication
  4. Synthetic routes to nanoconjugates of anthracyclines
    Authors:
    Kinga Piorecka, David Smith, Jan Kurjata, Maciej Stanczyk, Włodzimierz A. Stanczyk
    Academic press:
    Bioorganic Chemistry (rok: 2020, tom: 96, strony: 103617), Wydawca: elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioorg.2020.103617 - link to the publication
  5. Synthetic routes to nanomaterials containing anthracyclines: noncovalent systems
    Authors:
    Kinga Piorecka, Jan Kurjata, Maciej Stanczyk and Włodzimierz A. Stanczyk
    Academic press:
    Biomaterials Science (rok: 2018, tom: 6, strony: 2552-2565), Wydawca: ROYAL SOCIETY OF CHEMISTRY
    Status:
    Published
    DOI:
    10.1039/C8BM00739J - link to the publication

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