Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Iron chelators- the novel approach to anticancer therapy

2011/01/N/NZ4/01166

Keywords:

iron chelators thiosemicarbazones anticancer therapy

Descriptors:

  • NZ4_16:
  • ST5_16:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

UNIWERSYTET ŚLĄSKI w Katowicach, Wydział Matematyki Fizyki i Chemii

woj. śląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Maciej Serda 

Number of co-investigators in the project: 4

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 195 100 PLN

Project start date (Y-m-d): 2011-12-19

Project end date (Y-m-d): 2013-12-18

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. DESTYLARKA (6 000 PLN)
  2. Mieszadło magnetyczne z grzaniem (4 308 PLN)
  3. OPROGRAMOWANIE- PAKIET MOE (6 000 PLN)
  4. Wyparka rotacyjna (11 254 PLN)
  5. Zestaw Komputerowy (6 000 PLN)
  6. OPROGRAMOWANIE- PAKIET CHEMDRAW12 (CHEMOFFICE) (1 500 PLN)
  7. OPROGRAMOWANIE- PAKIET MESTRENOVA (1 000 PLN)
  8. OPROGRAMOWANIE- PAKIET DRAGON (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Microwave Assisted Synthesis of Monoazanaphthalene Scaffolds
    Authors:
    Wioleta Cieslik, Maciej Serda, Agata Kurczyk, Robert Musiol
    Academic press:
    Current Organic Chemistry (rok: 2013, tom: 17, strony: 491-503), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/1385272811317050006 - link to the publication
  2. Synthesis and characterization of quinoline-based thiosemicarbazones and correlation of cellular iron-binding efficacy to anti-tumor efficacy
    Authors:
    Maciej Serda , Danuta S. Kalinowski , Anna Mrozek-Wilczkiewicz , Robert Musiol , Agnieszka Szurko, Alicja Ratuszna , Namfon Pantarat , Zaklina Kovacevic , Angelica M. Merlot, Des R. Richardson , Jaroslaw Polanski
    Academic press:
    Bioorganic & Medicinal Chemistry Letters (rok: 2012, tom: 22, strony: 5527–5531), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmcl.2012.07.030 - link to the publication
  3. Synthesis, characterization and molecular structure of Ru(II) complex with benzoylpyrazine carboxylic acid derivatives
    Authors:
    J.G. Małecki, A. Maron, M. Serda, M. Dolezal, J. Polański
    Academic press:
    Polyhedron (rok: 2012, tom: 41, strony: 104-114), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.poly.2012.04.033 - link to the publication
  4. Ruthenium(II) carbonyl complexes of with thiosemicarbazone ligands
    Authors:
    J.G. Małecki, A.Maroń, M.Serda, J.Polański
    Academic press:
    Polyhedron (rok: 2013, tom: 56, strony: 44–54), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.poly.2013.03.045 - link to the publication
  5. Investigation of the Biological Properties of (Hetero) Aromatic Thiosemicarbazones
    Authors:
    Serda M., Mrozek-Wilczkiewicz A.; Jampilek J.; Pesko M.; Kralova K.; Vejsova M.; Musiol R.; Ratuszna A.; Polanski J
    Academic press:
    Molecules (rok: 2012, tom: 17, strony: 13483-13502), Wydawca: MDPI - Open Access Publishing
    Status:
    Published
    DOI:
    10.3390/molecules171113483 - link to the publication
  6. Iron Chelators in Photodynamic Therapy Revisited:Synergestic Effect by Novel Highly Active Thiosemicarbazones
    Authors:
    Anna Mrozek-Wilczkiewicz, Maciej Serda, Robert Musiol, Jan Grzegorz Malecki, Agnieszka Szurko, Angelika Muchowicz, Jakub Gołąb, Alicja Ratuszna, Jarosław Polański
    Academic press:
    ACS Medicinal Chemsitry Letters (rok: 2014, tom: 5, strony: 336-339), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/ml400422a - link to the publication
  7. Microwave assisted synthesis, X-ray crystallography and DFT calculations of selected aromatic thiosemicarbazones
    Authors:
    Maciej Serda, Jan G. Małecki, Anna Mrozek-Wilczkiewicz, Robert Musioł, Jarosław Polański
    Academic press:
    Journal of Molecular Structure (rok: 2013, tom: 1037, strony: 63-72), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2012.11.050 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy