Projects funded by the NCN


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248 projects found matching your search criteria :

  1. The role of histone-modifying enzymes in the epigenetics and pathogenesis of periodontitis.

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Aleksander M Grabiec

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  2. NanoBioCat: Developing biopolymer-based and protein friendly ionic liquids assisted enzyme nano-constructs with improved...

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Dibyendu Mondal

    Instytut Genetyki Roślin PAN

  3. Structural and functional studies of the plant enzymes of arginine metabolism as molecular targets of novel plant protec...

    Call: SONATA 17 , Panel: NZ1

    Principal investigator: dr Bartosz Sekuła

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  4. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  5. Research on the influence of medicines of the angiotensin-converting enzyme inhibitors (ACEI) group on the choroidal and...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Jowita Zwolska

    Uniwersytet Przyrodniczy w Lublinie, Wydział Medycyny Weterynaryjnej

  6. Dependence of growth of young pig from protein qualitative digestion - peptide vs. amino acid absorption

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Kamil Krzysztof Zaworski

    Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

  7. Fruits of Hylocereus polyrhizus clones as an alternative source of acylated betacyanin pigments in preparation of micros...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: dr Katarzyna Gabriela Sutor-Świeży

    Politechnika Krakowska im. Tadeusza Kościuszki

  8. Involvement of vacuolar processing enzyme (VPE) and lipase in the degradation of autophagic bodies in cells embryo axes ...

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: Szymon Stefaniak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  9. Chemical composition, antioxidant properties and related molecular mechanisms of action of matcha green tea extracts - i...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Joanna Alicja Kika

    Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Nauk o Zdrowiu

  10. Searching for the power of hormesis - Effects of silver nanoparticles, graphene oxide (GO), and GO-Ag composite on the f...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Reyhaneh Seyed Alian

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  11. Assessment of changes in mitochondria and the activity of selected enzymes and mitochondrial proteins in freshwater shri...

    Call: PRELUDIUM 20 , Panel: NZ8

    Principal investigator: Anna - Ostróżka

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  12. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Katarzyna Rut

    Politechnika Wrocławska

  13. Long-term exposure to high copper: does it affect the production of pancreatic digestive enzymes?

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Daria Patrycja Krzysztofik

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  14. Role of roots of selected trees species in soil organic matter stabilization and in shaping microbial activity of forest...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Karolina Staszel-Szlachta

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  15. Biotechnological and pharmacological potential of bee products microbiota.

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr hab. Piotr Szweda

    Politechnika Gdańska, Wydział Chemiczny

  16. Chiroptical properties of proteins and their complexes (CRISPR/Cas-RNA), and their relationship to biological activity

    Call: SONATINA 5 , Panel: ST4

    Principal investigator: dr Monika Anna Hałat

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Biotechnologii i Ogrodnictwa

  17. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Aleksander Siedlecki

    Instytut Biochemii i Biofizyki PAN

  18. Exploring metal ion cooperativity in binuclear transition metal sites

    Call: OPUS 20 (LAP) , Panel: ST4

    Principal investigator: dr hab. Dorota Anna Rutkowska-Żbik

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  19. Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m...

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Adam Maciej Kubas

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  20. Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the c...

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Artur Wiktor Góra

    Politechnika Śląska, Centrum Biotechnologii

  21. Enzymes of the L-methionine biosynthetic pathway as novel moleculartargets for antifungal chemotherapy

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Iwona Aniela Gabriel

    Politechnika Gdańska, Wydział Chemiczny

  22. Deadwood as microbial hotspots in mountain forest soils

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: dr hab. Ewa Błońska

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Leśny

  23. Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Tomasz Marcin Wróbel

    Uniwersytet Medyczny w Lublinie

  24. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  25. Application of PROTAC strategy for controlling Rab geranylgeranyl transferase and Rab proteins

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Magdalena Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  26. Designing of peroxidases-based biocatalytic system for a bio-mitigation of emerging contaminants

    Call: POLS , Panel: ST8

    Principal investigator: dr Muhammad Bilal

    Politechnika Poznańska, Wydział Technologii Chemicznej

  27. In search of adaptive strategies in obligatory predators - The immunological mechanisms in reared model spider species S...

    Call: OPUS 19 , Panel: NZ8

    Principal investigator: dr hab. Grażyna Iwona Wilczek

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  28. Drug metabolizing enzymes (DMEs) in liver pathology, proteomic characteristics, transcriptional and epigenetic regulatio...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Marek Droździk

    Pomorski Uniwersytet Medyczny w Szczecinie

  29. Towards automatic derivation of geometry-based descriptors as surrogates for complex structural approaches in enzyme-sub...

    Call: PRELUDIUM 19 , Panel: NZ2

    Principal investigator: Carlos Eduardo Sequeiros Borja

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  30. Modern nanoparticle and model organism - a toxic relation? Physiological and cellular causes of developmental disorders ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Maria Jadwiga Augustyniak

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  31. Exploring the mechanisms of therapy-facilitated metastasis and CAAX proteins-processing enzymes in liver cancer

    Call: OPUS 19 , Panel: NZ4

    Principal investigator: dr Jarosław Marek Cisowski

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  32. Biotechnological potential and antimicrobial activity of biosurfactant-lipase conjugates immobilized on biopolymers

    Call: OPUS 19 , Panel: NZ9

    Principal investigator: dr Tomasz Wojciech Janek

    Uniwersytet Przyrodniczy we Wrocławiu, Wydział Biotechnologii i Nauk o Żywności

  33. Aromatisation of steroids in marine bivalves: characteristic of enzymatic complex and process efficiency under the prese...

    Call: OPUS 19 , Panel: NZ8

    Principal investigator: dr hab. Anna Małgorzata Hallmann

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  34. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  35. Porous carbons with a basal plane-embedded Fe-N4 single-atom sites: versatile (electro)catalysts for electroprotic react...

    Call: OPUS 19 , Panel: ST5

    Principal investigator: dr hab. Wojciech Kiciński

    Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego, Wydział Nowych Technologii i Chemii

  36. The role of mitochondrial energy metabolism in shaping the quality of berry fruit stored in ozone-enriched atmosphere.

    Call: OPUS 18 , Panel: NZ9

    Principal investigator: dr Tomasz Marian Piechowiak

    Uniwersytet Rzeszowski

  37. Application of voltammetry and gravimetry for simultaneous detection of matrix metalloproteinases -1, -2 and -9 in human...

    Call: OPUS 18 , Panel: ST4

    Principal investigator: prof. Anna Maria Nowicka

    Uniwersytet Warszawski, Wydział Chemii

  38. The KLIKK proteases of human pathogen Tannerella forsythia: putative virulence factors with unique biochemical and struc...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  39. The effects of carbamylation on the activity and biological function of Angiotensin I Converting Enzyme (ACE1)

    Call: PRELUDIUM 18 , Panel: NZ1

    Principal investigator: Marta Kamińska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  40. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta - Jankowska

    Uniwersytet Gdański, Wydział Chemii

  41. Biodegradation of estrogens using advanced immobilized oxidoreductases-based biocatalytic systems

    Call: SONATA 15 , Panel: ST8

    Principal investigator: dr Jakub Łukasz Zdarta

    Politechnika Poznańska, Wydział Technologii Chemicznej

  42. Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

    Call: SONATA 15 , Panel: NZ3

    Principal investigator: dr Barbara Anna Kutryb-Zając

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  43. Changes of the profile of fruits polyphenolic compounds under the influence of high pressure considering the activity of...

    Call: PRELUDIUM 17 , Panel: NZ9

    Principal investigator: Justyna Szczepańska

    Instytut Biotechnologii Przemysłu Rolno-Spożywczego im. prof. Wacława Dąbrowskiego

  44. Novel families of ADP-ribosyltransferases and proteins involved in ADP-ribosylation.

    Call: OPUS 17 , Panel: NZ2

    Principal investigator: dr hab. Krzysztof Piotr Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  45. Dietary polyphenols as thyroid peroxidase (TPO) modulators with multidirectional biological activity - a combined in vit...

    Call: OPUS 17 , Panel: NZ9

    Principal investigator: prof. Urszula Katarzyna Gawlik

    Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

  46. How dysfunction in the nuclear, RNA degrading enzyme DIS3 leads to mitotic defects creating a possible therapeutic strat...

    Call: SONATINA 3 , Panel: NZ2

    Principal investigator: dr Tomasz M. Kuliński

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  47. Novel, rationally designed modulators of glycosomal import of enzymes in Trypanosoma parasites

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Maciej Filip Dawidowski

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  48. Structure and function of fumarate-adding gltcyl radical enzymes: biochemistry, modeling and application

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: prof. Maciej Szaleniec

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  49. Characterization of hydrolysates and peptides derived from oat kernels proteins in the context of their activity in dise...

    Call: PRELUDIUM 16 , Panel: NZ9

    Principal investigator: dr Monika Anna Pliszka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  50. Search for structure-antimicrobial activity correlation for selected boraheterocycles

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Sergiusz Mariusz Luliński

    Politechnika Warszawska, Wydział Chemiczny