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Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Effects of ethylene glycol ethers on oxidative stress and key enzymes of glucose metabolism in some regions of the brain.

2011/01/B/NZ7/00136

Keywords:

2- ethoxyethanol 2- butoxyethanol 2- phenoxyethanol oxidative stress glucose metabolism apoptosis rat SH-SY5Y cell line

Descriptors:

  • NZ1_2: Biochemistry
  • NZ3_7: Signal transduction
  • NZ4_4: Pathophysiology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Bogusława Budziszewska 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 396 200 PLN

Project start date (Y-m-d): 2011-12-07

Project end date (Y-m-d): 2014-12-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Analityczny czytnik wielopłytkowy z dyspenserami (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (4)
  1. Ethylene glycol ethers induce apoptosis and disturb glucose metabolism in the rat brain
    Authors:
    Bartosz Pomierny, Weronika Krzyżanowska, Ewa Niedzielska, Żaneta Broniowska, Bogusława Budziszewska
    Academic press:
    Pharmacological Reports (rok: 2015, tom: brak, strony: brak), Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    10.1016/j.pharep.2015.08.006 - link to the publication
  2. Ethylene Glycol Ethers Induce Oxidative Stress in the Rat Brain
    Authors:
    Pomierny B,. Krzyżanowska W., Smaga I., Pomierny-Chamioło L., Stankowicz P., Budziszewska B.
    Academic press:
    Neurotoxicity Research (rok: 2014, tom: 26, strony: 422-429), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-014-9486-8 - link to the publication
  1. Cytotoxic and proapoptotic effects of ethylene glycol ethers and their metabolites on the SH-SY5Y cel line.
    Authors:
    Pomierny B., Krzyżanowska W., Smaga I., Stankowicz P, Rospond B., Budziszewska B.
    Conference:
    XVIII International Congress of the Polish Pharmacological Society (rok: 2013, ), Wydawca: Pharmacological Reports, 2013, 65, 130
    Data:
    konferencja 23-25 maj 2013
    Status:
    Published
    DOI:
    link to the publication
  2. Ethylene glycol ethers induce oxidative stress in the rat brain
    Authors:
    Pomierny B., Krzyżanowska W., Budziszewska B.
    Conference:
    Society for Neuroscience; Advancing the Understanding of the Brain and Nervous System (rok: 2014, ), Wydawca: Society of Neuroscience
    Data:
    konferencja 15-19 listopad, 2014
    Status:
    Published
  3. The effects of ethylene glycol ethers on oxidative status of certain brain structures in rats
    Authors:
    Krzyżanowska W., Pomierny B., Smaga I., Rospond B., Budziszewska B.
    Conference:
    XVIII International Congress of the Polish Pharmacological Society (rok: 2013, ), Wydawca: Pharmacological Reports, 2013, 65, Suppl.1, 123
    Data:
    konferencja 23-25 maj 2013
    Status:
    Published
    DOI:
    link to the publication
  4. Effects of ethylene glycol ethers on oxidative stress markers
    Authors:
    Bartosz Pomierny, Bogusława Budziszewska
    Conference:
    The Twenty First Days of Neuropsychopharmacology (rok: 2012, ), Wydawca: Pharmacological Reports 2012 vol 64 issue 2, pp.468
    Data:
    konferencja Ustroń-Jaszowiec, 10-13 czerwiec 2012
    Status:
    Published
    DOI:
    link to the publication

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