Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New biocatalytic systems: carbon nanomaterial - enzyme, with controlled activity and potential application in anticancer therapies

2017/27/N/ST5/02696

Keywords:

L-asparaginase immobilization carbon nanomaterials graphene oxide (GO) carbon quantum dots (CQDs) nanodiamonds (NDs) anticancer therapies acute lymphoblastic leucemia

Descriptors:

  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • ST5_1: Structural properties of materials

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Mikołaja Kopernika, Wydział Chemii

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paulina Erwardt 

Number of co-investigators in the project: 3

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 207 500 PLN

Project start date (Y-m-d): 2018-07-23

Project end date (Y-m-d): 2021-07-22

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wirówka preparatywna z termostatowaniem (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. A new approach to obtaining nano-sized graphene oxide for biomedical applications
    Authors:
    Bolibok Paulina, Szymczak Bartosz, Roszek Katarzyna, Terzyk A. P., Wiśniewski Marek
    Academic press:
    Materials (rok: 2021, tom: 14, strony: 1327), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14061327 - link to the publication
  2. New Insight into the Fluorescence Quenching of Nitrogen-Containing Carbonaceous Quantum Dots—From Surface Chemistry to Biomedical Applications
    Authors:
    Marek Wiśniewski, Joanna Czarnecka, Paulina Bolibok, Michał Świdziński, Katarzyna Roszek
    Academic press:
    Materials (rok: 2021, tom: 14, strony: 2454), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14092454 - link to the publication
  3. Carbonaceous nanomaterials-mediated defense against oxidative stress
    Authors:
    Forbot Natalia, Bolibok Paulina, Wiśniewski Marek, Roszek Katarzyna
    Academic press:
    Mini-Reviews in Medicinal Chemistry (rok: 2020, tom: 20, strony: 294-307), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/1389557519666191029162150 - link to the publication
  4. Cytotoxic or Not? Disclosing the Toxic Nature ofCarbonaceous Nanomaterials throughNano–Bio Interactions
    Authors:
    Joanna Czarnecka, Marek Wiśniewski, Natalia Forbot, Paulina Bolibok,Artur P. Terzyk and Katarzyna Roszek
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 595), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13092060 - link to the publication
  5. Liquid phase adsorption induced nanosizing of graphene oxide
    Authors:
    Paulina Bolibok, Stanisław Koter, Anna Kaczmarek - Kędziera, Piotr Kowalczyk, Bogna Łukomska, Olga Łukomska, Sławomir Boncel, Marek Wiśniewski, Katsumi, Kaneko, Artur P. Terzyk
    Academic press:
    Carbon (rok: 2021, tom: 183, strony: 948-957), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.carbon.2021.07.101 - link to the publication
  6. Determination of graphene oxide adsorption space by lysozyme uptake – mechanistic studies
    Authors:
    Erwardt Paulina, Roszek Katarzyna, Wiśniewski Marek
    Academic press:
    Journal of Physical Chemistry Letters (tom: -, strony: -), Wydawca: American Chemical Society
    Status:
    Submitted
    DOI:
    brak - link to the publication

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