Projects funded by the NCN
The role of histone-modifying enzymes in the epigenetics and pathogenesis of periodontitis.
2021/43/B/NZ5/03165
Keywords:
epigenetics posttranslational histone modifications periodontitis Porphyromonas gingivalis fibroblast macrophage
Descriptors:
- NZ5_003:
- NZ3_001:
- NZ6_004:
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 22 - announced on 2021-09-15
Amount awarded: 2 095 112 PLN
Project start date (Y-m-d): 2022-10-03
Project end date (Y-m-d): 2026-10-02
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Inhibition of BTK and SYK attenuates Porphyromonas gingivalis -induced activation of the pyroptosis pathway and inflammation in host cellsAuthors:Alicja Plonczynska, Aureliusz Schuster, Dominika M Drapala, Tomasz Kaczmarzyk, Magdalena Nowak, Jan Potempa, Aleksander M Grabiec, Maja SochalskaAcademic press:Journal of Oral Microbiology (rok: 2025, tom: 17, strony: 2577219), Wydawca: Taylor & FrancisStatus:PublishedDOI:10.1080/20002297.2025.2577219 - link to the publication