The role for thiol-dependent antioxidant enzymes in estrogen receptor-positive breast cancer
2014/13/B/NZ5/01354
Keywords
Descriptors
- NZ3_7: Przekaźnictwo sygnału
- NZ2_9: Biologia systemowa
- NZ5_3: Patogeneza chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
Voivodeship: mazowieckie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
OPUS 7 – announced on 2014-03-17
- Amount awarded
- 1 213 233 PLN
- Project start date
- 2015-01-29
- Project end date
- 2018-07-28
- Project duration
- 42 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (2)
-
Harnessing altered oxidative metabolism in cancer by augmented prooxidant therapy
- Authors:
- Malgorzata Firczuk, Malgorzata Bajor, Agnieszka Graczyk-Jarzynka, Klaudyna Fidyt, Agnieszka Goral, Radoslaw Zagozdzon
- Academic press:
- Cancer Letters (year: 2020, volume: 471, pages: 46033), Publisher: ScienceDirect - Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.canlet.2019.11.037 – link to the publication
-
Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitizes these cells to prooxidant agents
- Authors:
- Malgorzata Bajor, Agata O. Zych, Agnieszka Graczyk-Jarzynka, Angelika Muchowicz, Malgorzata Firczuk, Lech Trzeciak, Pawel Gaj, Antoni Domagala, Marta Siernicka, Agnieszka Zagozdzon, Pawel Siedlecki, Monika Kniotek, Patrick C. O'Leary, Jakub Golab and Radoslaw Zagozdzon
- Academic press:
- British Journal of Cancer (year: 2018, volume: 7, pages: 873-884), Publisher: Springer Nature Limited
- Status:
- Published
- DOI:
- 10.1038/s41416-018-0263-y – link to the publication