Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the combination of analysis of intramolecular voids dynamics and enzymes evolution study
2020/39/B/ST4/03220
Keywords
Descriptors
- ST4_009: Chemia biologiczna
- ST4_004: Chemia teoretyczna i obliczeniowa
- NZ8_008: Ekotoksykologia
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Politechnika Śląska, Centrum Biotechnologii
Voivodeship: śląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 10
Call
OPUS 20 – announced on 2020-09-15
- Amount awarded
- 2 072 400 PLN
- Project start date
- 2021-10-04
- Project end date
- 2026-09-03
- Project duration
- 59 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Comprehensive analysis of acetylcholinesterase inhibitor and reactivator complexes: implications for drug design and antidote development
- Authors:
- Weronika Bagrowska, Angelika Karasewicz, Artur Góra
- Academic press:
- Drug Discovery Today (year: 2024, volume: 29(12), pages: 104217), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.drudis.2024.104217 – link to the publication