Search results

51. Novel therapy for pulmonary hypertension with dual mechanism of action: Myo-inositol trispyrophosphate targeting both pu…

Principal investigator: dr hab. Michał Maria Mączewski

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Call: OPUS 18, Panel: NZ5

52. Synthetic analogues of opioid growth factor linked to derivatives of glucosamine as a potential compounds for targeted t…

Principal investigator: prof. Iwona Maria Inkielewicz-Stępniak

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 18, Panel: NZ7

53. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

Principal investigator: dr hab. Aneta Katarzyna Rogalska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: SONATA BIS 9, Panel: NZ7

54. Synthesis and biofunctionalization of boron-rich nanoparticles; the application in targeted boron neutron capture therap…

Principal investigator: dr hab. Elżbieta Pajtasz-Piasecka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: OPUS 17, Panel: NZ5

55. Multimodal gold nanoparticles as potential radiopharmaceuticals in targeted radionuclide therapy

Principal investigator: dr Agnieszka Majkowska-Pilip

Instytut Chemii i Techniki Jądrowej

Call: SONATA 14, Panel: ST4

56. The effect of tumor microenvironment on efficiency of melanoma targeted therapy

Principal investigator: prof. Dorota Nowak

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 15, Panel: NZ5

57. In vitro studies of NaA nanozeolite functionalized with integrins inhibitor- cilengitide and labeled with radium radioiz…

Principal investigator: dr Sylwia Męczyńska-Wielgosz

Instytut Chemii i Techniki Jądrowej

Call: SONATA 12, Panel: NZ7

58. Hyphenated separation techniques in the study of the molecular mechanisms of metabolic biotransformation of drugs for ta…

Principal investigator: dr Małgorzata Szultka-Młyńska

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: SONATA 12, Panel: ST4

59. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte…

Principal investigator: Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ7

60. Nanomolecular antioxidants: biological basis of targeted therapy of neurodegenerative diseases.

Principal investigator: dr hab. Izabela Anna Sadowska-Bartosz

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Call: SONATA BIS 6, Panel: NZ7

61. Conformational epitopes of canine leukocyte antigens DR (DLA-DR) as targets diagnosis and experimental therapy of lympho…

Principal investigator: Marta Lisowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 11, Panel: NZ5

62. Targeting Nrf2-ARE pathway for chemoprevention and /or therapy of the liver and the pancreas cancers by naturally occurr…

Principal investigator: dr hab. Violetta Katarzyna Krajka-Kuźniak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: OPUS 11, Panel: NZ5

63. Nanotheranostics dedicated to targeted anticancer therapies: Novel magnetic hybrid carbon-based materials - synthesis an…

Principal investigator: Artur Kasprzak

Politechnika Warszawska, Wydział Chemiczny

Call: PRELUDIUM 11, Panel: ST5

64. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa…

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ4

65. In vitro and in vivo preclinical studies of NaA nanozeolite functionalized with antibodies anti-PSMA and labeled with ra…

Principal investigator: prof. Anna Małgorzata Lankoff

Instytut Chemii i Techniki Jądrowej

Call: OPUS 10, Panel: NZ7

66. Nanoparticle conjugates with the monoclonal antibody - a new opening in target tumor therapy

Principal investigator: Monika Anna Marcinkowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 10, Panel: NZ3

67. Developing of a new system for targeted anticancer therapy based on betulin derivetive and self-organizing polymeric nan…

Principal investigator: prof. Janusz Edward Kasperczyk

Śląski Uniwersytet Medyczny w Katowicach, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej w Sosnowcu

Call: HARMONIA 7, Panel: ST5

68. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho…

Principal investigator: dr hab. Robert Piotr Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 8, Panel: NZ3

69. The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe…

Principal investigator: prof. Joanna Benigna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 5, Panel: NZ3

70. Cancer progression- the role of tumor-derived microfragments (oncosomes) as messangers in communication between tumor ce…

Principal investigator: dr Rafał Michał Szatanek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: OPUS 4, Panel: NZ6

71. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop…

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

Call: MAESTRO 3, Panel: NZ4

72. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche…

Principal investigator: dr Ewelina Zabost

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA 3, Panel: ST5

73. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Principal investigator: dr Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ4

74. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi…

Principal investigator: dr hab. Joanna Gabriela Mika

Instytut Farmakologii PAN

Call: OPUS 2, Panel: NZ4

75. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms…

Principal investigator: dr Wojciech Stanisław Placha

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: SONATA 1, Panel: NZ4

76. Liposomal theranostic agent for magnetic resonance imaging and photodynamic therapy

Principal investigator: dr Paulina Krystyna Skupin-Mrugalska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Call: SONATA 11, Panel: NZ7

77. Efficiency biomarkers in photodynamic therapy against lung cancer

Principal investigator: dr Martyna Krzykawska-Serda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 2, Panel: NZ4

78. Dual-Target Compounds Modulating EAAT2 and Kv7.2/3 Channels: A Rational Strategy Toward Novel Antiseizure and Antinocice…

Principal investigator: dr Michał Andrzej Abram

Uniwersytet Jagielloński

Call: OPUS 29, Panel: NZ7

79. Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o…

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Call: OPUS 27, Panel: NZ5

80. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co…

Principal investigator: dr hab. Danuta Dudzik

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Call: OPUS 26, Panel: NZ7

81. Gaining control on XBP1s signaling as a starting point for novel cancer therapies

Principal investigator: prof. Rafał Artur Bartoszewski

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 24, Panel: NZ7

82. Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera…

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: WEAVE-UNISONO, Panel: NZ7

83. Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies …

Principal investigator: dr Natalia Bednarz-Knoll

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Call: OPUS 20, Panel: NZ5

84. Dual-targeted biodegradable polymeric micelles for anticancer drug delivery

Principal investigator: dr Katarzyna Jelonek

Centrum Materiałów Polimerowych i Węglowych PAN

Call: SONATA BIS 9, Panel: NZ7

85. Novel core-shell micro-sized systems for macrophage-targeted drug delivery via phagocytosis

Principal investigator: dr Tomasz Marek Urbaniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Call: PRELUDIUM 17, Panel: NZ7

86. The role of insulin signaling in melanoma maintenance and response to targeted therapeutics

Principal investigator: Marta Osrodek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 13, Panel: NZ3

87. Efficacy, toxicity and immunogenicity of carriers made of bioengineered spider silk for targeted drug delivery

Principal investigator: dr hab. Hanna Dams-Kozłowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Call: OPUS 8, Panel: NZ7

88. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets …

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: OPUS 4, Panel: NZ7

89. Regulation of ALKBH proteins expression in cancer and its role in cancer therapy.

Principal investigator: prof. Elżbieta Grzesiuk

Instytut Biochemii i Biofizyki PAN

Call: OPUS 2, Panel: NZ4

90. PIM kinases as rational therapeutic targets in lymphoid malignancies.

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 2, Panel: NZ4

91. Identification and targeting molecular drug resistance mechanisms in adult B-cell acute lymphoblastic leukemia

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 1, Panel: NZ4

92. Investigation of the mechanism of enhanced liposome delivery to tumors and its application for dual target immunotherapy

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 28, Panel: NZ7

93. Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t…

Principal investigator: dr Jan Marian Suski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: SONATA BIS 14, Panel: NZ3

94. Targeting enzymes of the parasite's purine salvage pathway as a new approach to combat H. pylori infections, including t…

Principal investigator: prof. Maria Agnieszka Bzowska

Uniwersytet Warszawski, Wydział Fizyki

Call: OPUS 26, Panel: NZ1

95. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie…

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

Call: SONATA 19, Panel: NZ5

96. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden…

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Call: PRELUDIUM 22, Panel: NZ5

97. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p…

Principal investigator: prof. Tomasz Adam Gośliński

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM BIS 4, Panel: NZ7

98. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Call: POLONEZ BIS 3, Panel: NZ5

99. Searching for new therapeutic targets in polyglutamine diseases

Principal investigator: prof. Marta Olejniczak

Instytut Chemii Bioorganicznej PAN

Call: OPUS 22, Panel: NZ2

100. Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

Principal investigator: dr Karolina Szczepanowska

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Call: SONATA BIS 11, Panel: NZ3

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