Multimodal gold nanoparticles as potential radiopharmaceuticals in targeted radionuclide therapy

2018/31/D/ST4/01488

Keywords

Descriptors

  • ST4_16: Chemia jądrowa i radiacyjna
  • ST4_2: Nanochemia
  • ST4_18: Inne zagadnienia pokrewne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Chemii i Techniki Jądrowej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Agnieszka Majkowska-Pilip

Number of co-investigators in the project: 4

Call

SONATA 14 – announced on 2018-09-14

Amount awarded
776 400 PLN
Project start date
2019-07-01
Project end date
2023-06-30
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. komputer z oprogramowaniem. Cost: 10 000 PLN
  2. mikroskop fluorescencyjny wraz z kamerą. Cost: 100 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Lipidic Cubic-Phase Nanoparticles (Cubosomes) Loaded with Doxorubicin and Labeled with 177Lu as a Potential Tool for Combined Chemo and Internal Radiotherapy for Cancers

    Authors:
    Adrianna Cytryniak, Ewa Nazaruk, Renata Bilewicz, Emilia Górzyńska, Kinga Żelechowska-Matysiak, Rafał Walczak, Adam Mames, Aleksander Bilewicz, Agnieszka Majkowska-Pilip*
    Academic press:
    Nanomaterials (year: 2020, volume: 10, pages: 2286), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10112272 – link to the publication
  2. Nanoparticles in Targeted Alpha Therapy

    Authors:
    Agnieszka Majkowska-Pilip*, Weronika Gawęda, Kinga Żelechowska-Matysiak, Kamil Wawrowicz, Aleksander Bilewicz
    Academic press:
    Nanomaterials (year: 2020, volume: 10, pages: 1366-1391), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10071366 – link to the publication
  3. Improvement of the effectiveness of HER2+ cancer therapy by use of doxorubicin and trastuzumab modified radioactive gold nanoparticles

    Authors:
    Kinga Żelechowska-Matysiak, Evangelia-Alexandra Salvanou, Penelope Bouziotis, Tadeusz Budlewski, Aleksander Bilewicz, Agnieszka Majkowska-Pilip
    Academic press:
    Molecular Pharmceutics (year: 2023, volume: 20, pages: 4676-4686), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.3c00414 – link to the publication
  4. Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers

    Authors:
    K. Żelechowska-Matysiak, K. Wawrowicz, M. Wierzbicki, T. Budlewski, A. Bilewicz, A. Majkowska-Pilip
    Academic press:
    Molecules (year: 2023, volume: 28(6), pages: 2451), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28062451 – link to the publication

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