Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Multimodal gold nanoparticles as potential radiopharmaceuticals in targeted radionuclide therapy

2018/31/D/ST4/01488

Keywords:

radiopharmaceuticals cancer cells gold nanoparticles chemotherapeutic doxorubicin neuroendocrine tumours

Descriptors:

  • ST4_16: Ionic liquids
  • ST4_2: Spectroscopic and spectrometric techniques
  • ST4_18: Radiation and nuclear chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii i Techniki Jądrowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Majkowska-Pilip 

Number of co-investigators in the project: 4

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 776 400 PLN

Project start date (Y-m-d): 2019-07-01

Project end date (Y-m-d): 2023-06-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. mikroskop fluorescencyjny wraz z kamerą (100 000 PLN)
  2. komputer z oprogramowaniem (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Lipidic Cubic-Phase Nanoparticles (Cubosomes) Loaded with Doxorubicin and Labeled with 177Lu as a Potential Tool for Combined Chemo and Internal Radiotherapy for Cancers
    Authors:
    Adrianna Cytryniak, Ewa Nazaruk, Renata Bilewicz, Emilia Górzyńska, Kinga Żelechowska-Matysiak, Rafał Walczak, Adam Mames, Aleksander Bilewicz, Agnieszka Majkowska-Pilip*
    Academic press:
    Nanomaterials (rok: 2020, tom: 10, strony: 2286), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10112272 - link to the publication
  2. Nanoparticles in Targeted Alpha Therapy
    Authors:
    Agnieszka Majkowska-Pilip*, Weronika Gawęda, Kinga Żelechowska-Matysiak, Kamil Wawrowicz, Aleksander Bilewicz
    Academic press:
    Nanomaterials (rok: 2020, tom: 10, strony: 1366-1391), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10071366 - link to the publication
  3. Improvement of the effectiveness of HER2+ cancer therapy by use of doxorubicin and trastuzumab modified radioactive gold nanoparticles
    Authors:
    Kinga Żelechowska-Matysiak, Evangelia-Alexandra Salvanou, Penelope Bouziotis, Tadeusz Budlewski, Aleksander Bilewicz, Agnieszka Majkowska-Pilip
    Academic press:
    Molecular Pharmceutics (rok: 2023, tom: 20, strony: 4676-4686), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.3c00414 - link to the publication
  4. Doxorubicin- and Trastuzumab-Modified Gold Nanoparticles as Potential Multimodal Agents for Targeted Therapy of HER2+ Cancers
    Authors:
    K. Żelechowska-Matysiak, K. Wawrowicz, M. Wierzbicki, T. Budlewski, A. Bilewicz, A. Majkowska-Pilip
    Academic press:
    Molecules (rok: 2023, tom: 28(6), strony: 2451), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28062451 - link to the publication

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