Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Efficiency biomarkers in photodynamic therapy against lung cancer

2011/03/N/NZ4/02019

Keywords:

cancer photodynamic therapy bacteriochlorin vessels targeting therapy hypoxia biomarkers

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ1_1: Molecular biology
  • NZ1_3: Biophysics

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Martyna Krzykawska-Serda 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 299 191 PLN

Project start date (Y-m-d): 2012-09-19

Project end date (Y-m-d): 2017-09-18

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Suszarka do szkiełek (2 500 PLN)
  2. Zestaw komputerowy (2 377 PLN)
  3. Aparat do elektroforezy oraz transferu na membranę nitrocelulozową.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (6)
  • Book publications / chapters in book publications (1)
  1. The role of strong hypoxia in tumors after treatment in the outcome of bacteriochlorin-based photodynamic therapy (PDT).
    Authors:
    Martyna Krzykawska-Serda, Janusz M. Dabrowski, Luis G Arnaut, Malgorzata Szczygiel, Krystyna Urbanska, Grazyna Stochel, Martyna Elas
    Academic press:
    Free Radical Biology and Medicine (rok: 2014, tom: 73, strony: 293-251), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2014.05.003 - link to the publication
  2. Nitrosylhemoglobin in photodynamically stressed human tumors growing in nude mice
    Authors:
    Monika Jakubowska, Dominika Michalczyk-Wetula, Janusz Pyka, Krystyna Urbańska, Beata K. Płonka, Patryk Kuleta, Piotr Łącki, Martyna Krzykawska-Serda, Leszek Fiedor, Przemysław M. Płonka
    Academic press:
    Nitric Oxide (rok: 2013, tom: 35, strony: 79-88), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.niox.2013.08.004 - link to the publication
  1. Obliteration or normalization of the blood vessels in murine tumors after F2BMet-PDT
    Authors:
    M. Krzykawska-Serda, J. M. Dąbrowski, K. Jasińska, M. Mamcarz, L. G. Arnaut, M. M. Pereira, G. Stochel, K. Urbańska, M. Elas
    Conference:
    The 14th World Congress of The International Photodynamic Association (rok: 2013, ), Wydawca: The International Photodynamic Association
    Data:
    konferencja 28-31.05.2013
    Status:
    Published
  2. F2Bmet-PDT effects on tumor vasculature
    Authors:
    M. Krzykawska-Serda, J. M. Dąbrowski, K. Jasińska, M. Mamcarz, E. Biela, J. Dobrucki, L. G. Arnaut, M. M. Pereira, G. Stochel, K. Urbańska, M. Elas
    Conference:
    Contemporary insights into cancer. Risk, perspectives, expectations. XL Jubilee Winter School Faculty of Biochemitry, Biophysics and Biotechnology (rok: 2013, ), Wydawca: Jagiellonian University
    Data:
    konferencja 16-21.02.13
    Status:
    Published
  3. Biomarkers after Bacteriochlorin Based Photodynamic Therapy against Cancer
    Authors:
    Martyna Krzykawska-Serda, Janusz M. Dabrowski, Katarzyna Jasinska, Malwina Karwicka, Luis G. Arnaut, Krystyna Urbanska, Grazyna Stochel, Martyna Elas
    Conference:
    EFMC-ISMC 2014 XXIII International Symposium on Medicinal Chemistry (rok: 2014, ), Wydawca: ChemMedChem, Wiley
    Data:
    konferencja 7-11 September 2014
    Status:
    Published
  4. Light dose dependent photodynamic efficacy with halogenated porphyrins and bacterichlorins
    Authors:
    Janusz M. Dabrowski, Martyna Krzykawska-Serda, Barbara Pucelik, Luis G. Arnaut, Krystyna Urbanska, Grazyna Stochel
    Conference:
    EACR Special Conference Cell Death in Cancer (rok: 2014, ), Wydawca: EACR
    Data:
    konferencja 30 Jan – 01 Feb 2014
    Status:
    Published
  5. 678: Photodynamic therapy effects on tumor vasculature and oxygenation in vivo
    Authors:
    M Krzykawska-Serda, K Jasinska, J Dabrowski, G Stochel, LG Arnaut, K Urbanska, M Elas
    Conference:
    EACR-23 (rok: 2014, ), Wydawca: Elsevier
    Data:
    konferencja 5-6.07.2014
    Status:
    Published
    DOI:
    link to the publication
  6. Cells surviving photodynamic effect exhibit lower metastatic potential
    Authors:
    Martyna Krzykawska-Serda, Monika Rak, Janusz Dabrowski, Ewa Podgorska, Martyna Elas, Luis G. Arnaut, Grazyna Stochel, Zbigniew Madeja, Krystyna Urbanska
    Conference:
    EACR Special Conference Cell Death in Cancer (rok: 2014, ), Wydawca: EACR
    Data:
    konferencja 30 Jan – 01 Feb 2014
    Status:
    Published
  1. Dermatological applications of EPR – skin-deep or in-depth?
    Authors:
    M. Krzykawska-Serda, D. Michalczyk-Wetula, P.M. Plonka
    Book:
    ESR Spectroscopy in Medicine (rok: 2019, tom: -, strony: 153-187), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    link to the publication

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