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Nanoparticle conjugates with the monoclonal antibody - a new opening in target tumor therapy

2015/19/N/NZ3/02942

Keywords

Descriptors

  • ST5_10: Nanomateriały: nanocząstki, nanorurki
  • NZ3_1: Biologia komórki
  • ST5_21: Chemia polimerów

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Monika Anna Marcinkowska

Number of co-investigators in the project: 3

Call

PRELUDIUM 10 – announced on 2015-09-15

Amount awarded
99 600 PLN
Project start date
2016-08-05
Project end date
2019-02-04
Project duration
30 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Multicomponent Conjugates of Anticancer Drugsand Monoclonal Antibody with PAMAM Dendrimers to IncreaseEfficacy of HER-2 Positive Breast Cancer Therapy

    Authors:
    Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Academic press:
    Pharmaceutical Research (year: 2019, volume: 36, pages: 154), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s11095-019-2683-7 – link to the publication

  2. Conjugate of PAMAM Dendrimer, Doxorubicin and Monoclonal Antibody—Trastuzumab: The New Approach of a Well-Known Strategy

    Authors:
    Monika Marcinkowska, Ewelina Sobierajska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Academic press:
    Polymers (year: 2018, volume: 10, pages: 187), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10020187 – link to the publication

  3. Molecular Mechanisms of Antitumor Activity of PAMAM Dendrimer Conjugates with Anticancer Drugs and a Monoclonal Antibody

    Authors:
    Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Gajek, Malgorzata Ksiezak, Paula Dzialak, Barbara Klajnert-Maculewicz
    Academic press:
    Polymers (year: 2019, volume: 11(9), pages: E1422), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/polym11091422 – link to the publication

Articles in post-conference publications (5)

  1. Conjugates of PAMAM dendrimer, taxanes and monoclonal antibody - a way to increase effectiveness in breast cancer therapy

    Authors:
    E. Sobierajska, M. Marcinkowska, A. Janaszewska, M. Stańczyk, B. Klajnert-Maculewicz
    Conference:
    CLINAM European Foundation for Clinical Nanomedicine (Basel) (year: 2016, pages: 4), Publisher: European Foundation for Clinical Nanomedicine
    Date:
    conference 26-29 czerwca
    Status:
    Published

  2. Nanoparticle conjugates with the monoclonal antibody – a new way in targeted tumor therapy

    Authors:
    M. Marcinkowska, E. Sobierajska,A. Janaszewska, B. Klajnert-Maculewicz
    Conference:
    24th Young Research Fellows' Meeting Of the French Medicinal Chemistry Society (year: 2017, pages: PC-021), Publisher: French Medicinal Chemistry Society (SCT)
    Date:
    conference 8-10 luty
    Status:
    Published

  3. Synteza i badanie cytotoksyczności koniugatów dendrymerów PAMAM

    Authors:
    M. Marcinkowska, E. Sobierajska, B. Klajnert-Maculewicz
    Conference:
    III Ogólnopolska Konferencja Doktorantów Nauk o Życiu – BioOpen (Łódź) (year: 2017, pages: P-71), Publisher: Uniwersytet Łódzki
    Date:
    conference 11-12 maja
    Status:
    Published

  4. DENDRIMER CONJUGATES WITH A MONOCLONAL ANTIBODY IN TARGETED TUMOR THERAPY

    Authors:
    Monika Marcinkowska, Anna Janaszewska, Barbara Klajnert-Maculewicz
    Conference:
    FIRST CA17140 Training School, University of Trieste (year: 2019, pages: 1), Publisher: University of Trieste
    Date:
    conference 8-11 kwietnia
    Status:
    Published

  5. Conjugates of PAMAM dendrimer, anticancer drug and monoclonal antibody: the new approach of a well–known strategy

    Authors:
    Anna Janaszewska, Monika Marcinkowska, Maciej Stanczyk, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Conference:
    Biodendrimer 2018: 6th International Symposium on Biomedical Applications of Dendrimers (year: 2018, pages: 1), Publisher: University of Urbino
    Date:
    conference 4-7 czerwca
    Status:
    Published

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