Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Nanoparticle conjugates with the monoclonal antibody - a new opening in target tumor therapy

2015/19/N/NZ3/02942

Keywords:

PAMAM dendrimers trastuzumab doxorubicin taxanes breast cancer

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • NZ3_1: Cell biology
  • ST5_21:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Monika Marcinkowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 99 600 PLN

Project start date (Y-m-d): 2016-08-05

Project end date (Y-m-d): 2019-02-04

Project duration:: 30 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. Multicomponent Conjugates of Anticancer Drugsand Monoclonal Antibody with PAMAM Dendrimers to IncreaseEfficacy of HER-2 Positive Breast Cancer Therapy
    Authors:
    Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Academic press:
    Pharmaceutical Research (rok: 2019, tom: 36, strony: 154), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11095-019-2683-7 - link to the publication
  2. Conjugate of PAMAM Dendrimer, Doxorubicin and Monoclonal Antibody—Trastuzumab: The New Approach of a Well-Known Strategy
    Authors:
    Monika Marcinkowska, Ewelina Sobierajska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Academic press:
    Polymers (rok: 2018, tom: 10, strony: 187), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10020187 - link to the publication
  3. Molecular Mechanisms of Antitumor Activity of PAMAM Dendrimer Conjugates with Anticancer Drugs and a Monoclonal Antibody
    Authors:
    Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Gajek, Malgorzata Ksiezak, Paula Dzialak, Barbara Klajnert-Maculewicz
    Academic press:
    Polymers (rok: 2019, tom: 11(9), strony: E1422), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym11091422 - link to the publication
  1. DENDRIMER CONJUGATES WITH A MONOCLONAL ANTIBODY IN TARGETED TUMOR THERAPY
    Authors:
    Monika Marcinkowska, Anna Janaszewska, Barbara Klajnert-Maculewicz
    Conference:
    FIRST CA17140 Training School, University of Trieste (rok: 2019, ), Wydawca: University of Trieste
    Data:
    konferencja 8-11 kwietnia
    Status:
    Published
  2. Synteza i badanie cytotoksyczności koniugatów dendrymerów PAMAM
    Authors:
    M. Marcinkowska, E. Sobierajska, B. Klajnert-Maculewicz
    Conference:
    III Ogólnopolska Konferencja Doktorantów Nauk o Życiu – BioOpen (Łódź) (rok: 2017, ), Wydawca: Uniwersytet Łódzki
    Data:
    konferencja 11-12 maja
    Status:
    Published
  3. Conjugates of PAMAM dendrimer, anticancer drug and monoclonal antibody: the new approach of a well–known strategy
    Authors:
    Anna Janaszewska, Monika Marcinkowska, Maciej Stanczyk, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
    Conference:
    Biodendrimer 2018: 6th International Symposium on Biomedical Applications of Dendrimers (rok: 2018, ), Wydawca: University of Urbino
    Data:
    konferencja 4-7 czerwca
    Status:
    Published
  4. Conjugates of PAMAM dendrimer, taxanes and monoclonal antibody - a way to increase effectiveness in breast cancer therapy
    Authors:
    E. Sobierajska, M. Marcinkowska, A. Janaszewska, M. Stańczyk, B. Klajnert-Maculewicz
    Conference:
    CLINAM European Foundation for Clinical Nanomedicine (Basel) (rok: 2016, ), Wydawca: European Foundation for Clinical Nanomedicine
    Data:
    konferencja 26-29 czerwca
    Status:
    Published
  5. Nanoparticle conjugates with the monoclonal antibody – a new way in targeted tumor therapy
    Authors:
    M. Marcinkowska, E. Sobierajska,A. Janaszewska, B. Klajnert-Maculewicz
    Conference:
    24th Young Research Fellows' Meeting Of the French Medicinal Chemistry Society (rok: 2017, ), Wydawca: French Medicinal Chemistry Society (SCT)
    Data:
    konferencja 8-10 luty
    Status:
    Published

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