Conformational epitopes of canine leukocyte antigens DR (DLA-DR) as targets diag

Conformational epitopes of canine leukocyte antigens DR (DLA-DR) as targets diagnosis and experimental therapy of lymphoma

2016/21/N/NZ5/01942

Keywords

Descriptors

NZ5_6: Diagnostyka chorób zwierząt
NZ5_8: Leczenie chorób zwierząt

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Marta Lisowska

Number of co-investigators in the project: 2

Call

PRELUDIUM 11 – announced on 2016-03-15

Amount awarded: 150 000 PLN
Project start date: 2017-01-27
Project end date: 2020-01-26
Project duration: 36 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

Laminar komórkowy klasy II bezpieczeństwa biologicznego. Cost: 30 000 PLN

Information in the final report

Publication in academic press/journals (2)

Development of novel monoclonal antibodies to dog leukocyte antigen DR (DLA-DR) displaying direct and immune-mediated cytotoxicity towards lymphoma cell lines

Authors:
Marta Lisowska, Aleksandra Pawlak, Justyna Kutkowska, Wojciech Hildebrand, Maciej Ugorski, Andrzej Rapak, Arkadiusz Miazek

Academic press:
Hematological Oncology (year: 2018, volume: 36, pages: 554-560), Publisher: Wiley

Status:
Published

DOI:
10.1002/hon.2507 – link to the publication
An antibody specific to dog leukocyte antigen DR (DLA-DR) and its novel methotrexate conjugate inhibit the growth of canine B cell lymphoma

Authors:
Lisowska M, Milczarek M, Ciekot J, Kutkowska J, Rapak A, Miazek A

Academic press:
Cancers (year: 2019, volume: 11, pages: 1438), Publisher: MDPI

Status:
Published

DOI:
10.3390/cancers11101438 – link to the publication

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