Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms of cancer progression

2011/01/D/NZ4/03401

Keywords:

PPAR ligands cytostatics statins cancers

Descriptors:

  • NZ4_17:
  • NZ4_11: Metabolism
  • NZ7_1: Epidemiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Wojciech Placha 

Number of co-investigators in the project: 10

Call: SONATA 1 - announced on 2011-03-15

Amount awarded: 649 000 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2015-12-15

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (4)
  1. A method of isolating and analysing drugs from cancer cells for preclinical research
    Authors:
    W. Placha, J. Zagajewski, P. Suder, M. Piwowar
    Academic press:
    Journal of Chromatography A (rok: 2022, tom: 1682, strony: 1873-3778), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2022.463500 - link to the publication
  2. METHOD FOR THE TREATMENT OF HUMAN MELANOMA
    Authors:
    dr Wojciech Placha, Dr Jacek Zagajewski (Katedra Biochemii UJCM) , Dr Monika Piwowar (Zakład Bioinformatyki i Telemedycyny UJCM), Dr Małgorzata Szczygieł
    Academic press:
    Amerykański Urządu Patentowy (rok: 2021, ), Wydawca: United States Patent and Trademark Office's (USPTO),
    Status:
    Published
  3. Informacja o wszęciu procedury patentowej
    Authors:
    nd
    Academic press:
    nd (rok: 2016, tom: nd, strony: nd), Wydawca: nd
    Status:
    Submitted
  4. A composition for the treatment of human melanoma
    Authors:
    Wojciech Placha, Jacek Zagajewski, Monika Piwowar, Małgorzata Szczygieł
    Academic press:
    World Intellectual Property Organization (rok: 2018, tom: 19.01.2018, strony: 45306), Wydawca: International Application Published Under The Patent Cooperation Treaty
    Status:
    Published
    DOI:
    PCT/PL2018/050002 - link to the publication
  5. The similarity of selected statins – a comparative analysis
    Authors:
    Constantin Dreyer, Wojciech Placha, Jacek Zagajewski, JacekDygut, Klaudia Stangel-Wójcikiewicz, Monika Piwowar
    Academic press:
    Bio-Algorithms and Med-Systems. (rok: 2018, tom: 45645, strony: 45296), Wydawca: De Gruyter
    Status:
    Published
    DOI:
    10.1515/bams-2018-0034 - link to the publication
  6. Blocking the drug resistance channel by selected hydrophobic statins in chemoresistance human melanoma
    Authors:
    Wojciech Placha *, Piotr Suder, Agnieszka Panek, Patrycja Bronowicka-Adamska, Marta Zarzycka *, Małgorzata Szczygieł, Jacek Zagajewski, Monika Weronika Piwowar
    Academic press:
    Biomolecules (rok: 2023, tom: 13, strony: brak), Wydawca: MDPI
    Status:
    Accepted for publication
    DOI:
    10.3390/xxxxx - link to the publication
  7. Combination of a taxane and a hydrophobic statins for the treatment of human melanoma
    Authors:
    Placha W, Zagajewski J, Piwowar M, Szczygieł M.
    Academic press:
    Europan Patent Office (rok: 2022, ), Wydawca: EPO EU
    Status:
    Accepted for publication
  8. Kompozycja do leczenia czerniaka u ludzi
    Authors:
    Wojciech Placha, Jacek Zagajewski, Monika Piwowar, Małgorzata Szczygieł
    Academic press:
    Urząd Patentowy Rzeczypospolitej Polskiej (rok: 2017, tom: PK/3945/RW, strony: 45309), Wydawca: Urząd Patentowy RP
    Status:
    Published
  1. Pharmaceutical composition in melanoma treatment in humans.
    Authors:
    Wojciech Placha, Jacek Zagajewski, Monika Piwowar.
    Conference:
    V Ogólnopolskie Sympozjum Biomedyczne ESKULAP (rok: 2018, ), Wydawca: Tygiel
    Data:
    konferencja 01-02.12.
    Status:
    Published
  2. - Kompozycja farmaceutyczna do leczenia czerniaka u ludzi
    Authors:
    Placha W, Szczygieł M, Zagajewski J, Piwowar M,
    Conference:
    XI edycja Multidyscyplinarnej Konferencji Nauki o Leku (rok: 2018, ), Wydawca: Polskie Towarzystwo Farmaceutyczne
    Data:
    konferencja 14 - 16 listopada
    Status:
    Published
  3. New applications of registered drugs.
    Authors:
    W Placha, . Kocemba, J Zagajewski, T Pociecha, T Sacha, M Zawada, S Czekalska
    Conference:
    2 ECOP (European Conference of Oncology Pharmacy) (rok: 2014, ), Wydawca: EJOP (European Journal of Oncology Pharmacy)
    Data:
    konferencja 26-28 June
    Status:
    Published
  4. Nuclear receptor PPAR-alpha - new application in oncology
    Authors:
    W Placha, K Kocemba, A Bentke, P Laidler
    Conference:
    IX Jakub K. Parnas Conference, Proteins from Birth to Death (rok: 2013, ), Wydawca: Joint Research Conference of the Israel Institute for Advanced Studies and the Israel Science Foundation
    Data:
    konferencja September 29 - October 2, 2013
    Status:
    Published