Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

2022/47/P/NZ5/01156

Keywords

Descriptors

  • NZ5_007: Leczenie chorób człowieka
  • NZ5_009: Inne zagadnienia pokrewne
  • NZ7_014: Farmacja, farmakoterapia, farmakologia

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Politechnika Wrocławska

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Marco Deiana

Number of co-investigators in the project: 3

Call

POLONEZ BIS 3 – announced on 2022-07-15

Amount awarded
1 202 944 PLN
Project start date
2023-10-01
Project end date
2025-09-30
Project duration
24 months (the same as in the proposal)
Project status
Project completed

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative

    Authors:
    Dudek, Marta López-Pacios, Lucía Sabouri, Nasim Nogueira, Juan J. Martinez-Fernandez, Lara Deiana, Marco
    Academic press:
    The Journal of Physical Chemistry Letters (year: 2024, volume: 15, pages: 9757-9765), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpclett.4c02285 – link to the publication
  2. Heavy-atom-free π-twisted photosensitizers for fluorescence bioimaging and photodynamic therapy

    Authors:
    Sánchez, Darío Puchán Morice, Korentin Mutovska, Monika G. Khrouz, Lhoussain Josse, Pierre Allain, Magali Gohier, Frédéric Blanchard, Philippe Monnereau, Cyrille Le Bahers, Tangui Sabouri, Nasim Zagranyarski, Yulian Cabanetos, Clement Deiana, Marco
    Academic press:
    Journal of Materials Chemistry B (year: 2024, volume: 12, pages: 8107-8121), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D4TB01014K – link to the publication
  3. A Rationally Designed Azobenzene Photoswitch for DNA G-Quadruplex Regulation in Live Cells

    Authors:
    Dudek, Marta López-Pacios, Lucia Sabouri, Nasim Nogueira, Juan Martinez-Fernandez, Lara Deiana, Marco
    Academic press:
    Angewandte Chemie International Edition (year: 2025, volume: 64, pages: e202413000 (1 of 12)), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/anie.202413000 – link to the publication
  4. Advancements in molecular disassembly of optical probes: a paradigm shift in sensing, bioimaging, and therapeutics

    Authors:
    Saczuk, Karolina Dudek, Marta Matczyszyn, Katarzyna Deiana, Marco
    Academic press:
    Nanoscale Horizons (year: 2024, volume: 9, pages: 1390-1416), Publisher: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D4NH00186A – link to the publication

European Commission logo This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 665778.

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Graphic design and implementation: Jakub Piotrowski