Cancer progression- the role of tumor-derived microfragments (oncosomes) as messangers in communication between tumor cells. Possible target of biological therapy in cancer.

2012/07/B/NZ6/03499

Keywords

Descriptors

  • NZ6_2: Immunologia kliniczna
  • NZ6_1: Odporność swoista i nieswoista
  • NZ6_8: Inne zagadnienia pokrewne

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Rafał Michał Szatanek

Number of co-investigators in the project: 12

Call

OPUS 4 – announced on 2012-09-15

Amount awarded
1 095 750 PLN
Project start date
2013-07-18
Project end date
2018-01-17
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Cytometr przepływowy o wysokiej czułości. Cost: 280 000 PLN
  2. System do analizy nanocząsteczek.

Information in the final report

Publication in academic press/journals (5)

  1. Autologous tumor‑derived microvesicles influence gene expression profiles and enhance protumorigenic chemotactic potential, signal transduction and cellular respiration in gastric cancer cells.

    Authors:
    Szatanek R, Weglarczyk K, Stec M1, Baran J, Parlinska-Wojtan M, Siedlar M, Baj-Krzyworzeka M
    Academic press:
    International Journal of Oncology (year: 2020, volume: Jan;56(1), pages: 359-367), Publisher: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijo.2019.4923 – link to the publication
  2. Isolation of extracellular vesicles: Determining the correct approach (Review).

    Authors:
    Szatanek R, Baran J, Siedlar M, Baj-Krzyworzeka M.
    Academic press:
    International Journal of Molecular Medicine (year: 2015, volume: 36, pages: 46343), Publisher: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijmm.2015.2194 – link to the publication
  3. Characterization of human gastric adenocarcinoma cell lines established form peritoneal ascites

    Authors:
    Mytar B, Stec M, Szatanek R, Węglarczyk K, Szewczyk K, Szczepanik A, Drabik G, Baran J, Siedlar M, Baj-Krzyworzeka M.
    Academic press:
    Oncology Letters (year: 2018, volume: Apr;15(4), pages: 4849-4858), Publisher: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol_2018.7995 – link to the publication
  4. Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells.

    Authors:
    Stec M, Szatanek R, Baj-Krzyworzeka M, Baran J, Zembala M, Barbasz J, Waligórska A, Dobrucki JW, Mytar B, Szczepanik A, Siedlar M, Drabik G, Urbanowicz B, Zembala M
    Academic press:
    Journal of Translational Medicine (year: 2015, volume: 13, pages: open access), Publisher: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12967-015-0737-0 – link to the publication
  5. The Methods of Choice for Extracellular Vesicles (EVs) Characterization.

    Authors:
    Szatanek R, Baj-Krzyworzeka M, Zimoch J, Lekka M, Siedlar M, Baran J.
    Academic press:
    International Journal of Molecular Sciences (year: 2017, volume: 18, pages: 46040), Publisher: MDPI Open Access Journals
    Status:
    Published
    DOI:
    10.3390/ijms18061153 – link to the publication

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