Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Cancer progression- the role of tumor-derived microfragments (oncosomes) as messangers in communication between tumor cells. Possible target of biological therapy in cancer.

2012/07/B/NZ6/03499

Keywords:

gastric cancer tumor cells genes microvesicles oncosomes

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ6_1: Adaptive and innate immunity
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Rafał Szatanek 

Number of co-investigators in the project: 12

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 1 095 750 PLN

Project start date (Y-m-d): 2013-07-18

Project end date (Y-m-d): 2018-01-17

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Cytometr przepływowy o wysokiej czułości (280 000 PLN)
  2. System do analizy nanocząsteczek.

Information in the final report

  • Publication in academic press/journals (5)
  1. Autologous tumor‑derived microvesicles influence gene expression profiles and enhance protumorigenic chemotactic potential, signal transduction and cellular respiration in gastric cancer cells.
    Authors:
    Szatanek R, Weglarczyk K, Stec M1, Baran J, Parlinska-Wojtan M, Siedlar M, Baj-Krzyworzeka M
    Academic press:
    International Journal of Oncology (rok: 2020, tom: Jan;56(1), strony: 359-367), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijo.2019.4923 - link to the publication
  2. The Methods of Choice for Extracellular Vesicles (EVs) Characterization.
    Authors:
    Szatanek R, Baj-Krzyworzeka M, Zimoch J, Lekka M, Siedlar M, Baran J.
    Academic press:
    International Journal of Molecular Sciences (rok: 2017, tom: 18, strony: 45309), Wydawca: MDPI Open Access Journals
    Status:
    Published
    DOI:
    10.3390/ijms18061153 - link to the publication
  3. Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells.
    Authors:
    Stec M, Szatanek R, Baj-Krzyworzeka M, Baran J, Zembala M, Barbasz J, Waligórska A, Dobrucki JW, Mytar B, Szczepanik A, Siedlar M, Drabik G, Urbanowicz B, Zembala M
    Academic press:
    Journal of Translational Medicine (rok: 2015, tom: 13, strony: open access), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12967-015-0737-0 - link to the publication
  4. Characterization of human gastric adenocarcinoma cell lines established form peritoneal ascites
    Authors:
    Mytar B, Stec M, Szatanek R, Węglarczyk K, Szewczyk K, Szczepanik A, Drabik G, Baran J, Siedlar M, Baj-Krzyworzeka M.
    Academic press:
    Oncology Letters (rok: 2018, tom: Apr;15(4), strony: 4849-4858), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ol_2018.7995 - link to the publication
  5. Isolation of extracellular vesicles: Determining the correct approach (Review).
    Authors:
    Szatanek R, Baran J, Siedlar M, Baj-Krzyworzeka M.
    Academic press:
    International Journal of Molecular Medicine (rok: 2015, tom: 36, strony: 45613), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijmm.2015.2194 - link to the publication

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