Projects funded by the NCN

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188 projects found matching your search criteria :

  1. Functional implications of brain-enriched circular RNAs

    Call: SONATA BIS 8 , Panel: NZ3

    Principal investigator: dr Monika Piwecka

    Instytut Chemii Bioorganicznej PAN

  2. Histidine Biosynthetic Pathway in Plants: Structural and Functional Studies as a Framework for the Design of Inhibitors ...

    Call: SONATA 14 , Panel: NZ1

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  3. Allele-selective therapy for polyglutamine diseases with the use of RNA interference technology

    Call: PRELUDIUM BIS 1 , Panel: NZ1

    Principal investigator: dr hab. Marta Olejniczak

    Instytut Chemii Bioorganicznej PAN

  4. Comprehensive analysis of the Schmidtea mediterranea transcriptome – identification of non-coding RNAs involved in cell ...

    Call: OPUS 18 , Panel: NZ2

    Principal investigator: dr hab. Paulina Maria Jackowiak

    Instytut Chemii Bioorganicznej PAN

  5. Antibiotic resistance genes and integrons as indicators of biotic pollution and resistance load of Arctic ecosystems

    Call: SONATINA 4 , Panel: NZ9

    Principal investigator: dr Nicoletta Diana Makowska-Zawierucha

    Instytut Chemii Bioorganicznej PAN

  6. Application of small compounds in the epigenetic therapy of malignant brain gliomas

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Mirosława Zofia Naskręt-Barciszewska

    Instytut Chemii Bioorganicznej PAN

  7. ABCG driven transport of phenylpropanoids in Medicago truncatula - a versatile but adapted scenario.

    Call: OPUS 20 , Panel: NZ9

    Principal investigator: prof. Michał Jasiński

    Instytut Chemii Bioorganicznej PAN

  8. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Weronika Paulina Kotkowiak

    Instytut Chemii Bioorganicznej PAN

  9. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  10. Investigation of a new therapeutic strategy to lower mutant protein in SCA3 / MJD

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: prof. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  11. Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor...

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: dr Konrad Mateusz Pakuła

    Instytut Chemii Bioorganicznej PAN

  12. Identification of molecular mechanisms involved in soybean's cold stress response in temperate climate conditions.

    Call: OPUS 8 , Panel: NZ9

    Principal investigator: prof. Tomasz Twardowski

    Instytut Chemii Bioorganicznej PAN

  13. Mechanisms underlying the targeting of coding sequence repeats by microRNA-like inhibitors

    Call: OPUS 8 , Panel: NZ1

    Principal investigator: dr Agnieszka Fiszer

    Instytut Chemii Bioorganicznej PAN

  14. Pathophysiological consequences of histone N-homocysteinylation in hyperhomocysteinemia caused by CBS deficiency

    Call: PRELUDIUM 8 , Panel: NZ5

    Principal investigator: Izabela Anna Lewandowska

    Instytut Chemii Bioorganicznej PAN

  15. RAN translation at CAG repeats in spinocerebellar ataxia type 3

    Call: SONATA 10 , Panel: NZ5

    Principal investigator: dr Magdalena Jazurek-Ciesiołka

    Instytut Chemii Bioorganicznej PAN

  16. Catalytic RNS's as a tool for human mitochondrial biotechnology

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Paweł Mariusz Głodowicz

    Instytut Chemii Bioorganicznej PAN

  17. The role of protein factors that bind to the 5' non-coding region of human p53 mRNA in regulation of p53 expression at t...

    Call: OPUS 11 , Panel: NZ1

    Principal investigator: prof. Jerzy Henryk Ciesiołka

    Instytut Chemii Bioorganicznej PAN

  18. Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

    Call: SONATA 11 , Panel: NZ3

    Principal investigator: dr Patrick McDevitt Perrigue

    Instytut Chemii Bioorganicznej PAN

  19. Unknown areas of activity of human ribonuclease Dicer

    Call: SONATA BIS 6 , Panel: NZ1

    Principal investigator: dr hab. Anna Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  20. Function of secondary structure of influenza A virus vRNA in ribonucleoprotein complex during viral life cycle

    Call: SONATINA 1 , Panel: NZ1

    Principal investigator: dr Elżbieta Lenartowicz

    Instytut Chemii Bioorganicznej PAN

  21. Shedding new light on genome's dark matter: identification of novel long non-coding RNAs in zebrafish

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

    Instytut Chemii Bioorganicznej PAN

  22. Mechanisms and developmental roles of transcription termination

    Call: OPUS 16 , Panel: NZ1

    Principal investigator: dr hab. Takashi Miki

    Instytut Chemii Bioorganicznej PAN

  23. Molecular basics of type II transmembrane serine proteases (TTSPs)-mediated activation of influenza viruses

    Call: BEETHOVEN LIFE 1 , Panel: NZ1

    Principal investigator: dr Paweł Zmora

    Instytut Chemii Bioorganicznej PAN

  24. Discovering disorders of brain development in Huntington disease as a consequence of putative total huntingtin deficienc...

    Call: OPUS 16 , Panel: NZ3

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  25. Sequence preferences of ribonucleases involved in human microRNA biogenesis.

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Włodzimierz Krzyżosiak

    Instytut Chemii Bioorganicznej PAN

  26. "RNA toxicity in pathogenesis of polyglutamine diseases"

    Call: MAESTRO 3 , Panel: NZ1

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  27. Defining new neurodegeneration mechanisms using the first SCA3/MJD knock-in mouse model.

    Call: SONATA BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Maciej Figiel

    Instytut Chemii Bioorganicznej PAN

  28. Dynasty and population of the Piast State in view of the integrated historical, anthropological and genomic studies

    Call: SYMFONIA 2 , Panel: NZ2

    Principal investigator: prof. Marek Marian Figlerowicz

    Instytut Chemii Bioorganicznej PAN

  29. RNA hybrid duplex-quadruplex structures with dual functionality as a new tool for silecing of gene expression

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Zofia Janina Gdaniec

    Instytut Chemii Bioorganicznej PAN

  30. Psychedelics as Therapeutic Candidates in Neurodegenerative Disorders Treatment– a Study in Spinocerebellar Ataxia Type ...

    Call: SONATINA 5 , Panel: NZ4

    Principal investigator: dr Urszula Joanna Kozłowska

    Instytut Chemii Bioorganicznej PAN

  31. Close Encounters of the Third Kind: what happens when ribonuclease Dicer encounters in the cell RNA and DNA adopting G-q...

    Call: OPUS 21 , Panel: NZ2

    Principal investigator: dr hab. Anna Maria Kurzyńska-Kokorniak

    Instytut Chemii Bioorganicznej PAN

  32. Exploring Ty3 genomic RNA structure during retrotransposition in yeast

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: Angelika Daria Andrzejewska-Romanowska

    Instytut Chemii Bioorganicznej PAN

  33. Non-canonical pre-mRNA splicing participates in the editing of CNBP mutant allele in myotonic dystrophy type 2 (DM2)

    Call: PRELUDIUM BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  34. Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr Katarzyna Klonowska

    Instytut Chemii Bioorganicznej PAN

  35. At the dawn of Central European statehood on the example of the Czechia and Poland. Dynasties - elites - societies (late...

    Call: OPUS 26 (LAP) , Panel: NZ8

    Principal investigator: prof. Marek Marian Figlerowicz

    Instytut Chemii Bioorganicznej PAN

  36. Identification of sequences motifs regulating splicing activity in maize under herbicide stress conditions

    Call: PRELUDIUM 1 , Panel: NZ9

    Principal investigator: Joanna Małgorzata Gracz

    Instytut Chemii Bioorganicznej PAN

  37. Determining the secondary structure and function of BC200 in human brain tumor.

    Call: PRELUDIUM 1 , Panel: NZ3

    Principal investigator: Patrycja Sosińska

    Instytut Chemii Bioorganicznej PAN

  38. Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Dagmara Baraniak

    Instytut Chemii Bioorganicznej PAN

  39. Interspecies metabolic engineering as a tool to investigate immune functions of plant specialized metabolites.

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  40. The use of genome editing systems in experimental therapy of polyglutamine diseases

    Call: ETIUDA 8 , Panel: NZ2

    Principal investigator: Magdalena Dąbrowska

    Instytut Chemii Bioorganicznej PAN

  41. Foldback triplex-forming oligonucleotides as novel tools for G-quadruplex unfolding and selective inhibition of c-Myc on...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  42. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  43. Non-coding RNAs at single-cell resolution in the pituitary gland and their role in the regulation of gene expression

    Call: OPUS 19 , Panel: NZ3

    Principal investigator: dr Monika Piwecka

    Instytut Chemii Bioorganicznej PAN

  44. Long term survival and oxidative stress in hyperhomocysteinemia

    Call: SONATA 9 , Panel: NZ5

    Principal investigator: dr Marta Sikora

    Instytut Chemii Bioorganicznej PAN

  45. Active transport systems as an element that controls the molecular cross-talk between symbionts during arbuscular mycorr...

    Call: SONATA 9 , Panel: NZ3

    Principal investigator: dr Joanna Banasiak

    Instytut Chemii Bioorganicznej PAN

  46. MicroRNA profiling in cellular models of Huntington's disease generated using iPSC technology

    Call: PRELUDIUM 9 , Panel: NZ2

    Principal investigator: dr Emilia Barbara Kozłowska

    Instytut Chemii Bioorganicznej PAN

  47. Molecular mechanisms underlying loss of a defensive metabolic pathway in a phylogenetic clade of plant species closely r...

    Call: OPUS 9 , Panel: NZ1

    Principal investigator: dr hab. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  48. Exploring second generation of nucleotide analogues containing phosphoranesulfen- or phosphoraneselenamides as new struc...

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: dr Justyna Gołębiewska

    Instytut Chemii Bioorganicznej PAN

  49. Deciphering the molecular causes and consequences of circular RNAs elevated expression levels in myotonic dystrophy type...

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  50. Development of stereospecific phosphorylating agents containing nucleophilic catalytic groups

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Michał Jerzy Sobkowski

    Instytut Chemii Bioorganicznej PAN

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