Projects funded by the NCN


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195 projects found matching your search criteria :

  1. Modulation of amygdala neural network activity by the 5-HT7 receptor

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  2. The role of synovial fibroblasts' activity in joint pain in osteoarthritis

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  3. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Justyna Józefa Brodowicz

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. The role of endoplasmic reticulum stress in the pathomechanisms of early-life stress-induced dysfunction of the prefrona...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Chocyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Karolina Kamińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  7. Evaluation of histopathological changes in the rats tissues after acute and chronic administration of the compounds from...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Edyta Dorota Możdżeń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  8. Pessimism as cognitive biomarker of depression in animal model

    Call: OPUS 7 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  10. Molecular mechanism of unique action of clozapine in the context of GPCR.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr Agata Faron-Górecka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. The influence of perinatal exposure to selective serotonin reuptake inhibitors on the structure and functions of mice do...

    Call: OPUS 14 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  12. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  13. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. Ocena roli wybranych białek neuronalnych i mikroglejowych w patogenezie schizofrenii - badania w modelu zwierzęcym.

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Katarzyna Anna Chamera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. Wykorzystanie metod uczenia maszynowego w zadaniach komputerowo wspomaganego projektowania leków.

    Call: ETIUDA 3 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  16. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Maria Nalepa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  17. Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human

    Call: OPUS 1 , Panel: NZ4

    Principal investigator: dr hab. Jacek Wójcikowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. Impact of endocrine disrupting chemicals - 4,para nonylphenol - on toxic effects mediated by xenobiotic receptors PXR an...

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Ewa Joanna Litwa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  19. Define the role and modulation of immune diabetes changed factors - their importance to the action of analgesics.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Magdalena Małgorzata Żychowska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  21. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  22. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Stanisław Detka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  28. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  29. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  30. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  31. The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Basińska-Ziobroń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Dariusz Marek Żurawek

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  33. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi...

    Call: PRELUDIUM 9 , Panel: ST6

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  34. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  35. Adaptacyjne podejmowanie decyzji u zwierząt z komórkowo specyficzną inaktywacją receptorów glutaminianu w układzie dopam...

    Call: ETIUDA 4 , Panel: NZ4

    Principal investigator: Przemysław Eligiusz Cieślak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  36. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  39. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Agata Zygmunt

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  40. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Zofia Kuter

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  42. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  43. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  44. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. "Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Gabriel Piotr Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. Involvement of astrocytes in the neuroprotective mechanism evoked by enhancement of noradrenergic transmission in trasng...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Justyna Beata Barut

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. Investigation of novel functionally selective opioid receptors agonists

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Łucja Elżbieta Szumiec

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  50. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Józef Wilczkowski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk