RAN translation at CAG repeats in spinocerebellar ataxia type 3
2015/19/D/NZ5/02183
Keywords
Descriptors
- NZ5_3: Patogeneza chorób człowieka
- NZ3_6: Neurobiologia komórkowa
- NZ2_3: Proteomika
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Instytut Chemii Bioorganicznej PAN
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
dr Magdalena Jazurek-Ciesiołka
Number of co-investigators in the project: 6
Call
SONATA 10 – announced on 2015-09-15
- Amount awarded
- 699 048 PLN
- Project start date
- 2016-09-01
- Project end date
- 2023-02-28
- Project duration
- 78 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Aparat do elektroforezy i transferu białek z wyposażeniem.
- pompa do perfuzji. Cost: 12 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions
- Authors:
- Ciesiolka A., Jazurek M., Drazkowska K., Krzyzosiak W.J.
- Academic press:
- Frontiers in Cellular Neuroscience (year: 2017, volume: 11, pages: 97), Publisher: Frontiers Media SA
- Status:
- Published
- DOI:
- 10.3389/fncel.2017.00097 – link to the publication
-
Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases
- Authors:
- Jazurek M., Ciesiolka A., Starega-Roslan J., Bilinska K., Krzyzosiak W.J.
- Academic press:
- Nucleic Acids Research (year: 2016, volume: 44, pages: 9050-9070), Publisher: Oxford University Press
- Status:
- Published
- DOI:
- 10.1093/nar/gkw803 – link to the publication
-
RAN translation of the expanded CAG repeats in the SCA3 disease context
- Authors:
- Magdalena Jazurek-Ciesiolka, Adam Ciesiolka, Alicja A. Komur, Martyna O. Urbanek-Trzeciak, Wlodzimierz J. Krzyzosiak, Agnieszka Fiszer
- Academic press:
- Journal of Molecular Biology (year: 2020, volume: 432, pages: 166699), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jmb.2020.10.033 – link to the publication