Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mechanisms and developmental roles of transcription termination

2018/31/B/NZ1/03580

Keywords:

RNA processing RNA degradation RNA-binding protein XRN2 Pumilio transcription termination Caenorhabditis elegans

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_1: Molecular genetics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Takashi Miki 

Number of co-investigators in the project: 5

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 723 960 PLN

Project start date (Y-m-d): 2019-09-03

Project end date (Y-m-d): 2023-05-02

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Projektor chemiluminescencyjny: Amersham Imager 680 lub podobny (90 000 PLN)
  2. Czytnik mikropłytek: PerkinElmer Victor Nivo 5F lub podobny (180 000 PLN)
  3. Komputer stacjonarny: Dell Vostro 3670 lub podobny (2 szt.) (10 000 PLN)
  4. Mikroskop stereo: Nikon SMZ800N lub podobny (2 szt.) (42 000 PLN)
  5. Aparat do PCR w czasie rzeczywistym: Thermo Fisher QuantStudio lub podobny (135 000 PLN)
  6. Inkubator: VWR INCU-Line IL 150R lub podobny (12 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Nuclear RNA Regulation by XRN2 and XTBD Family Proteins
    Authors:
    Ilkin Aygün, Takashi S. Miki
    Academic press:
    Cell Structure and Function (rok: 2021, tom: 46, strony: 73-78), Wydawca: Japan Society for Cell Biology
    Status:
    Published
    DOI:
    10.1247/csf.21041 - link to the publication
  2. A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans
    Authors:
    Ilkin Aygün, Alicja Rzepczak, Takashi S. Miki
    Academic press:
    Genetics and Molecular Biology (rok: 2023, tom: 46(2), strony: e20220328), Wydawca: Sociedade Brasileira de Genética
    Status:
    Published
    DOI:
    10.1590/1678-4685-GMB-2022-0328 - link to the publication

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