Function of secondary structure of influenza A virus vRNA in ribonucleoprotein complex during viral life cycle

2017/24/C/NZ1/00219

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_4: Biologia strukturalna
  • NZ1_10: Biologia drobnoustrojów

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Elżbieta Lenartowicz

Number of co-investigators in the project: 3

Call

SONATINA 1 – announced on 2016-12-15

Amount awarded
1 083 146 PLN
Project start date
2017-11-10
Project end date
2021-11-09
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. The effect of the PKR inhibitor, 2-aminopurine, on the replication of influenza A virus, and segment 8 mRNA splicing

    Authors:
    Dagny Lorent, Rafal Nowak, Monika Gazecka, Pawel Zmora, Elzbieta Lenartowicz Onyekaa
    Academic press:
    Open Life Sciences (year: 2025, volume: 20, pages: 20251098), Publisher: De Gruyter
    Status:
    Published
    DOI:
    10.1515/biol-2025-1098 – link to the publication
  2. RNA Secondary Structure Motifs of the Influenza A Virus as Targets for siRNA-Mediated RNA Interference

    Authors:
    J. Piasecka, E. Lenartowicz, M. Soszynska-Jozwiak, B. Szutkowska, R. Kierzek, E. Kierzek
    Academic press:
    Molecular Therapy - Nucleic Acid (year: 2020, volume: 19, pages: 627-642), Publisher: Cell Press
    Status:
    Published
    DOI:
    10.1016/j.o – link to the publication
  3. Secondary structure of the segment 5 genomic RNA of influenza A virus and its application for designing antisense oligonucleotides

    Authors:
    Michalak P, Soszynska-Jozwiak M, Biala E, Moss WN, Kesy J, Szutkowska B, Lenartowicz E, Kierzek R, Kierzek E
    Academic press:
    Scientific Reports (year: 2019, volume: 9, pages: 3801), Publisher: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-019-40443-7 – link to the publication

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