Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Histone demethylase JMJD3 as an epigenetic regulator in the senescence-associated secretory phenotype and cancer

2016/21/D/NZ3/00641

Keywords:

epigenetics chromatin cancer senescence

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ3_4: Ageing

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Patrick Perrigue 

Number of co-investigators in the project: 5

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 632 400 PLN

Project start date (Y-m-d): 2017-02-17

Project end date (Y-m-d): 2020-11-16

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. wirówka (10 000 PLN)
  2. Komputer z oprogramowaniem (MS Office, pakiet Corell, pakiet Adobe, Endnote, GraphPad Prism) oraz wyposażeniem (mysz, klawiatura). (12 000 PLN)
  3. Inkubator do hodowli Wypławków (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Total DNA Methylation Changes Reflect Random Oxidative DNA Damage in Gliomas
    Authors:
    Anna-Maria Barciszewska, Małgorzata Giel-Pietraszuk, Patrick M. Perrigue, Mirosława Naskręt-Barciszewska
    Academic press:
    Cells (rok: 2019, tom: 8(9), strony: 1065), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8091065 - link to the publication
  2. Cancer stem cell-inducing media activates senescence reprogramming in fibroblasts
    Authors:
    Patrick M Perrigue, Magdalena Rakoczy, Kamila P Pawlicka, Agnieszka Belter, Małgorzata Giel-Pietraszuk, Mirosława Naskręt-Barciszewska, Jan Barciszewski, Marek Figlerowicz
    Academic press:
    Cancers (rok: 2020, tom: 12(7), strony: 1745), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/cancers12071745 - link to the publication
  1. Depletion of histone H3K27me3 is an epigenetic stress that induces cellular senescence in fibroblasts
    Authors:
    Patrick M. Perrigue, Kamila Pawlicka, Justyna Obacz, Marek Figlerowicz, Jan Barciszewski
    Conference:
    Congress BIO2018 (rok: 2018, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 18-21.09.2018
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy