Projects funded by the NCN

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192 projects found matching your search criteria :

  1. Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts

    Call: OPUS 21 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej PAN

  2. Identification of sequences motifs regulating splicing activity in maize under herbicide stress conditions

    Call: PRELUDIUM 1 , Panel: NZ9

    Principal investigator: Joanna Małgorzata Gracz

    Instytut Chemii Bioorganicznej PAN

  3. Development of stereospecific phosphorylating agents containing nucleophilic catalytic groups

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Michał Jerzy Sobkowski

    Instytut Chemii Bioorganicznej PAN

  4. Structural proteomics of mulberry silkworm hemolymph

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Grzegorz Dariusz Bujacz

    Instytut Chemii Bioorganicznej PAN

  5. New 3,8-disubstituted purine nucleoside analogues as prospective application for research of structure and biological ac...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr hab. Anna Pasternak

    Instytut Chemii Bioorganicznej PAN

  6. Development of chemical method for synthesis of biologically active triphosphates using thermolabile protecting groups

    Call: OPUS 4 , Panel: ST5

    Principal investigator: dr hab. Marcin Krzysztof Chmielewski

    Instytut Chemii Bioorganicznej PAN

  7. ABA transport in legumes - between drought stress responses and nitrogen fixation efficiency

    Call: HARMONIA 5 , Panel: NZ3

    Principal investigator: dr hab. Michał Jasiński

    Instytut Chemii Bioorganicznej PAN

  8. Elucidation of the mechanisms that induce copy number polymorphism of large genome fragments and of the relations betwee...

    Call: OPUS 7 , Panel: NZ2

    Principal investigator: prof. Marek Marian Figlerowicz

    Instytut Chemii Bioorganicznej PAN

  9. Understanding the mechanism of action for small molecule kinase inhibitors in alleviating myotonic dystrophy type 1 (DM1...

    Call: OPUS 7 , Panel: NZ5

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej PAN

  10. Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  11. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis-Sobocińska

    Instytut Chemii Bioorganicznej PAN

  12. Molecular basis of glucosinolate modification and activation in the immunity of Brassicaceae species

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: prof. Paweł Bednarek

    Instytut Chemii Bioorganicznej PAN

  13. Transcriptome-wide analysis of RNA structure in the cell and across cellularcompartments, and identification of the impa...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Katarzyna Pachulska-Wieczorek

    Instytut Chemii Bioorganicznej PAN

  14. Identification of cancer-driver mutations in non-coding parts of protein-coding genes and long non-coding RNA genes

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: prof. Piotr Kozłowski

    Instytut Chemii Bioorganicznej PAN

  15. The use of artificial miRNAs in the therapy of Huntington's Disease

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: dr Anna Kotowska-Zimmer

    Instytut Chemii Bioorganicznej PAN

  16. Thrombin binding aptamer with expanded chemical diversity as potential anticoagulant and anticancer agent

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Weronika Paulina Kotkowiak

    Instytut Chemii Bioorganicznej PAN

  17. Investigation of DNA repair mechanisms in DRPLA model using CRISPR-Cas system

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: dr Magdalena Dąbrowska

    Instytut Chemii Bioorganicznej PAN

  18. Relationship between ATPase activity stimulation and transport - the case of selective Medicago truncatula ABCG transpor...

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: dr Konrad Mateusz Pakuła

    Instytut Chemii Bioorganicznej PAN

  19. Exploring Ty3 genomic RNA structure during retrotransposition in yeast

    Call: PRELUDIUM 20 , Panel: NZ3

    Principal investigator: dr Angelika Daria Andrzejewska-Romanowska

    Instytut Chemii Bioorganicznej PAN

  20. Functional or not functional? Studying positionally conserved vertebrate lncRNA orthologues at subcellular resolution

    Call: SONATA BIS 11 , Panel: NZ2

    Principal investigator: dr hab. Barbara Uszczyńska-Ratajczak

    Instytut Chemii Bioorganicznej PAN

  21. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  22. Structure-guided design of histone demethylase inhibitors for cancer therapy.

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Piotr Henryk Małecki

    Instytut Chemii Bioorganicznej PAN

  23. Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type i...

    Call: OPUS 23 , Panel: ST4

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  24. Functional characterization of ABCG transporters present in Medicago truncatula seeds

    Call: OPUS 24 , Panel: NZ9

    Principal investigator: prof. Michał Jasiński

    Instytut Chemii Bioorganicznej PAN

  25. Antisense oligonucleotides as tools specifically binding viral G-quadruplexes and their experimental verification

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr Marta Maria Szabat

    Instytut Chemii Bioorganicznej PAN

  26. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej PAN

  27. In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

    Call: OPUS 10 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej PAN

  28. Role of microRNAs in regulation iron metabolism in Friedreich's ataxia

    Call: OPUS 10 , Panel: NZ1

    Principal investigator: dr hab. Marek Napierała

    Instytut Chemii Bioorganicznej PAN

  29. Bifunctional antisense oligonucleotides - optimization of alternative splicing regulation in cancer cell lines

    Call: SONATA 11 , Panel: NZ5

    Principal investigator: dr Jolanta Agnieszka Lisowiec-Wąchnicka

    Instytut Chemii Bioorganicznej PAN

  30. Ekspression of circular RNA in myotonic dystrophy type 1 - implications to pathogenesis

    Call: PRELUDIUM 11 , Panel: NZ5

    Principal investigator: dr Karol Czubak

    Instytut Chemii Bioorganicznej PAN

  31. Designing a new method for direct identification and absolute quantification of premature transcription termination even...

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: dr Piotr Jan Machtel

    Instytut Chemii Bioorganicznej PAN

  32. Cotranscriptional folding of influenza virus RNA in MDCK cells in presence of antisense oligonucleotides. A new method f...

    Call: OPUS 13 , Panel: NZ1

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  33. Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

    Call: SONATA 13 , Panel: NZ2

    Principal investigator: dr hab. Anna Wojakowska

    Instytut Chemii Bioorganicznej PAN

  34. Contribution of gene copy number polymorphism to natural variation in response of Arabidopsis thaliana ecotypes to bioti...

    Call: SONATA 13 , Panel: NZ2

    Principal investigator: dr hab. Agnieszka Jowita Żmieńko

    Instytut Chemii Bioorganicznej PAN

  35. Mechanisms of human gene expression regulation by uridilation

    Call: SONATA 13 , Panel: NZ1

    Principal investigator: dr hab. Zbigniew Stanisław Warkocki

    Instytut Chemii Bioorganicznej PAN

  36. Changes in the ribosomal protein composition and in the ribosome-associated small noncoding RNAs in Saccharomyces cerevi...

    Call: OPUS 14 , Panel: NZ1

    Principal investigator: dr hab. Kamilla Grzywacz

    Instytut Chemii Bioorganicznej PAN

  37. Pioneering structural and functional studies of miRNA G-quadruplexes

    Call: SONATINA 2 , Panel: NZ1

    Principal investigator: dr Agnieszka Belter

    Instytut Chemii Bioorganicznej PAN

  38. Thermodynamic parameters and rules towards the determination of RNA folding in in vivo-like conditions. RNA folding pred...

    Call: OPUS 17 , Panel: ST4

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej PAN

  39. Arc as a neuronal Gag. Exploring the viral properties and functions of a master regulator of synaptic plasticity.

    Call: PRELUDIUM 18 , Panel: NZ1

    Principal investigator: dr Julita Gumna

    Instytut Chemii Bioorganicznej PAN

  40. Insights in the phenylpropanoid transport in model legume plant Medicago truncatula

    Call: SONATA 19 , Panel: NZ9

    Principal investigator: dr Wanda Ada Biała-Leonhard

    Instytut Chemii Bioorganicznej PAN

  41. Unravelling the conservation of crossover hotspots and regulation of meiotic recombination at the pericentromeres

    Call: SONATINA 8 , Panel: NZ2

    Principal investigator: dr Maja Magdalena Szymańska-Lejman

    Instytut Chemii Bioorganicznej PAN

  42. Comprehensive structural and functional analysis of p53 mRNA to identify secondary and tertiary RNA structures important...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Leszek Michał Błaszczyk

    Instytut Chemii Bioorganicznej PAN

  43. Thrombotic Mechanisms in Human Cystathionine β-Synthase Deficiency

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: prof. Hieronim Jakubowski

    Instytut Chemii Bioorganicznej PAN

  44. Structural studies of proteins crucial for tick-mammal-pathogen interactions.

    Call: OPUS 9 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  45. The use of genetic tools in experimental therapy of polyglutamine diseases.

    Call: SONATA BIS 5 , Panel: NZ2

    Principal investigator: dr hab. Marta Olejniczak

    Instytut Chemii Bioorganicznej PAN

  46. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej PAN

  47. The role of membrane transporters in the cytokinin signaling upon Legume- Rhizobia Symbiosis

    Call: OPUS 10 , Panel: NZ9

    Principal investigator: dr hab. Michał Jasiński

    Instytut Chemii Bioorganicznej PAN

  48. The APOBEC3B deletion - analysis of its role in familial breast cancer predisposition and determination of its consequen...

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: dr Katarzyna Klonowska

    Instytut Chemii Bioorganicznej PAN

  49. Anticoagulant and antiproliferative properties of novel thrombin binding aptamer analogues

    Call: PRELUDIUM 10 , Panel: NZ5

    Principal investigator: Weronika Paulina Kotkowiak

    Instytut Chemii Bioorganicznej PAN

  50. Identification of CAG repeat-binding proteins and imaging RNA-protein interactions in cells

    Call: OPUS 10 , Panel: NZ2

    Principal investigator: dr Adam Kazimierz Ciesiołka

    Instytut Chemii Bioorganicznej PAN

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