Structural studies of proteins crucial for tick-mammal-pathogen interactions.

2015/17/B/NZ1/00873

Keywords

Descriptors

  • NZ1_4: Biologia strukturalna
  • NZ1_1: Biologia molekularna
  • NZ2_2: Genomika, transkryptomika i epigenomika

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Mariusz Jaskólski

Number of co-investigators in the project: 4

Call

OPUS 9 – announced on 2015-03-16

Amount awarded
806 000 PLN
Project start date
2016-01-27
Project end date
2020-01-26
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. refraktometr. Cost: 4 000 PLN
  2. zestaw komputerowy (2 pcs). Cost: 10 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Borrelia outer surface protein C is capable of human fibrinogen binding

    Authors:
    Paulina Bierwagen, Kamil Szpotkowski, Mariusz Jaskolski, Anna Urbanowicz
    Academic press:
    FEBS Journal (year: 2019, volume: 286(12), pages: 2415-2428), Publisher: Federation of European Biochemical Societies
    Status:
    Published
    DOI:
    10.1111/febs.14810 – link to the publication
  2. Strong interactions between Salp15 homologues from the tick I. ricinus and distinct types of the outer surface OspC protein from Borrelia

    Authors:
    Paulina Bierwagen, Joanna Śliwiak, Mariusz Jaskolski, AnnaUrbanowicz
    Academic press:
    Ticks and Tick-borne Diseases (year: 2021, volume: 12, pages: 101630), Publisher: ELSEVIER GMBH
    Status:
    Published
    DOI:
    10.1016/j.ttbdis.2020.101630 – link to the publication

Articles in post-conference publications (1)

  1. Outer surface protein C (OspC) from Borrelia is capable of fibrinogen binding

    Authors:
    Paulina Bierwagen, Kamil Szpotkowski, Mariusz Jaskolski, Anna Urbanowicz
    Conference:
    43rd FEBS Congress (year: 2018, pages: 198), Publisher: Federation of European Biochemical Societies
    Date:
    conference 7-12 lipiec
    Status:
    Published

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