Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Structural studies of proteins crucial for tick-mammal-pathogen interactions.

2015/17/B/NZ1/00873

Keywords:

tick Ixodes Borrelia intrinsically disordered proteins protein-protein interaction

Descriptors:

  • NZ1_4: Structural biology
  • NZ1_1: Molecular biology
  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mariusz Jaskólski 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 806 000 PLN

Project start date (Y-m-d): 2016-01-27

Project end date (Y-m-d): 2020-01-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zestaw komputerowy (2 szt.) (10 000 PLN)
  2. refraktometr (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Borrelia outer surface protein C is capable of human fibrinogen binding
    Authors:
    Paulina Bierwagen, Kamil Szpotkowski, Mariusz Jaskolski, Anna Urbanowicz
    Academic press:
    FEBS Journal (rok: 2019, tom: 286(12), strony: 2415-2428), Wydawca: Federation of European Biochemical Societies
    Status:
    Published
    DOI:
    10.1111/febs.14810 - link to the publication
  2. Strong interactions between Salp15 homologues from the tick I. ricinus and distinct types of the outer surface OspC protein from Borrelia
    Authors:
    Paulina Bierwagen, Joanna Śliwiak, Mariusz Jaskolski, AnnaUrbanowicz
    Academic press:
    Ticks and Tick-borne Diseases (rok: 2021, tom: 12, strony: 101630), Wydawca: ELSEVIER GMBH
    Status:
    Published
    DOI:
    10.1016/j.ttbdis.2020.101630 - link to the publication
  1. Outer surface protein C (OspC) from Borrelia is capable of fibrinogen binding
    Authors:
    Paulina Bierwagen, Kamil Szpotkowski, Mariusz Jaskolski, Anna Urbanowicz
    Conference:
    43rd FEBS Congress (rok: 2018, ), Wydawca: Federation of European Biochemical Societies
    Data:
    konferencja 7-12 lipiec
    Status:
    Published

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