Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Function and dysfunction of repeated tracts in non-coding and protein-coding transcripts

2021/41/B/NZ3/03803

Keywords:

CAG repeat tracts polyglutamine diseases non-coding RNAs RNA-RNA interactions protein-protein interactions

Descriptors:

  • NZ3_005:
  • NZ2_002:
  • NZ1_001:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Fiszer 

Number of co-investigators in the project: 6

Call: OPUS 21 - announced on 2021-03-15

Amount awarded: 2 103 000 PLN

Project start date (Y-m-d): 2022-02-01

Project end date (Y-m-d): 2026-01-31

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
    Authors:
    Paweł Joachimiak, Adam Ciesiołka, Emilia Kozłowska, Paweł M Świtoński, Grzegorz Figura, Agata Ciołak, Grażyna Adamek, Magdalena Surdyka, Żaneta Kalinowska-Pośka, Maciej Figiel, Nicholas S Caron, Michael R Hayden, Agnieszka Fiszer
    Academic press:
    BMC BIology (rok: 2023, tom: 21, strony: article number 17), Wydawca: BioMed Central Ltd
    Status:
    Published
    DOI:
    10.1186/s12915-023-01515-3 - link to the publication
  2. Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models
    Authors:
    Paweł Joachimiak, Adam Ciesiołka, Emilia Kozłowska, Paweł M Świtoński, Grzegorz Figura, Agata Ciołak, Grażyna Adamek, Magdalena Surdyka, Żaneta Kalinowska-Pośka, Maciej Figiel, Nicholas S Caron, Michael R Hayden, Agnieszka Fiszer
    Academic press:
    BMC BIology (rok: 2023, tom: 21, strony: article number 17), Wydawca: BioMed Central Ltd
    Status:
    Published
    DOI:
    10.1186/s12915-023-01515-3 - link to the publication
  3. Atrophin-1 Function and Dysfunction in Dentatorubral–Pallidoluysian Atrophy
    Authors:
    Bartosz Nowak, Emilia Kozlowska, Weronika Pawlik, Agnieszka Fiszer
    Academic press:
    Movement Disorders (rok: 2023, tom: 38, strony: 526-536), Wydawca: WILEY
    Status:
    Published
    DOI:
    10.1002/mds.29355 - link to the publication
  4. RNA regulation in brain function and disease 2022 (NeuroRNA): A conference report
    Authors:
    Monika Piwecka, Agnieszka Fiszer, Katarzyna Rolle, Marta Olejniczak
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2023, tom: 16, strony: 133209), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fnmol.2023.1133209 - link to the publication
  5. Insights into RNA-mediated pathology in new mouse models of Huntington's disease
    Authors:
    Magdalena Wozna-Wysocka, Magdalena Jazurek-Ciesiolka, Lukasz Przybyl, Dorota Wronka, Julia Oliwia Misiorek, Joanna Suszynska-Zajczyk, Grzegorz Figura, Adam Ciesiolka, Paula Sobieszczanska, Anna Zeller, Magdalena Niemira, Pawel Michal Switonski, Agnieszka Fiszer
    Academic press:
    FASEB Journal (rok: 2024, tom: 38, strony: e70182), Wydawca: WILEY
    Status:
    Published
    DOI:
    10.1096/fj.202401465R - link to the publication

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