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Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

2017/26/D/NZ2/00964

Keywords

Descriptors

  • NZ2_4: Metabolomika
  • NZ2_3: Proteomika
  • NZ5_1: Etiologia chorób człowieka

Panel

NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Anna Wojakowska

Number of co-investigators in the project: 5

Call

SONATA 13 – announced on 2017-06-14

Amount awarded
1 546 211 PLN
Project start date
2018-04-13
Project end date
2023-07-12
Project duration
63 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. Metabolic Profiles of Whole Serum and Serum-Derived Exosomes Are Different in Head and Neck Cancer Patients Treated by Radiotherapy

    Authors:
    Anna Wojakowska , Aneta Zebrowska, Agata Skowronek, Tomasz Rutkowski, Krzysztof Polanski, Piotr Widlak, Lukasz Marczak, Monika Pietrowska
    Academic press:
    Journal of Personalized Medicine (year: 2020, volume: 10, pages: 229), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm10040229 – link to the publication

  2. Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy

    Authors:
    Wojakowska A, Marczak L, Zeman M, Chekan M, Zembala-Nożyńska E, Polanski K, Strugała A, Widlak P, Pietrowska M.
    Academic press:
    Frontiers in Oncology (year: 2024, volume: 14, pages: 1323961), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2024.1323961 – link to the publication

  3. Metabolome of Exosomes: Focus on Vesicles Released by Cancer Cells and Present in Human Body Fluids

    Authors:
    Aneta Zebrowska, Agata Skowronek, Anna Wojakowska, Piotr Widlak, Monika Pietrowska
    Academic press:
    International Journal of Molecular Sciences (year: 2019, volume: 20, pages: Article Number: 3461), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20143461 – link to the publication

  4. Molecular Composition of Serum Exosomes Could Discriminate Rectal Cancer Patients with Different Responses to Neoadjuvant Radiotherapy

    Authors:
    Urszula Strybel, Łukasz Marczak, Marcin Zeman, Krzysztof Polanski, Łukasz Mielańczyk, Olesya Klymenko, Anna Samelak-Czajka, Paulina Jackowiak, Mateusz Smolarz, Mykola Chekan, Ewa Zembala-Nożyńska, Piotr Widlak, Monika Pietrowska, Anna Wojakowska
    Academic press:
    Cancers (year: 2022, volume: 14, pages: 993), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14040993 – link to the publication

Articles in post-conference publications (3)

  1. Multi-omic approach for studying molecular components of serum-derived sEV andtumor tissue of rectal cancer patients with different response to neoadjuvant radiotherapy.

    Authors:
    Urszula Strybel; Lukasz Marczak; Marcin Zeman; Mykola Chekan; Ewa Zembala-Nozynska; ŁukaszMielanczyk; Monika Pietrowska; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (year: 2022, pages: 270), Publisher: Journal of Extracellular Vesicles/Wiley Online Library
    Date:
    conference 25-29.05.2022
    Status:
    Published

  2. Proteomic and metabolomic composition of serum-derived small extracellular vesiclescould discriminate rectal cancer patients with different responses to neoadjuvant radiotherapy

    Authors:
    Urszula Strybel; Lukasz Marczak; Marcin Zeman; Krzysztof Polanski; Łukasz Mielanczyk; Mateusz Smolarz; Piotr Widlak; MonikaPietrowska; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (year: 2022, pages: 189), Publisher: Journal of Extracellular Vesicles/Wiley Online Library
    Date:
    conference 25-29.05.2022
    Status:
    Published

  3. Proteomic profiles of small extracellular vesicles released by colon cancer cell line HCT116 with different p53 status

    Authors:
    Monika Pietrowska; Mateusz Smolarz; Marta Gawin; Urszula Strybel; Marek Rusin; Piotr Widlak; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (year: 2022, pages: 160), Publisher: Journal of Extracellular Vesicles/Wiley Online Library
    Date:
    conference 25-29.05.2022
    Status:
    Published

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