Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of biomolecules released by colorectal cancer cells and detected in serum or/and exosomes

2017/26/D/NZ2/00964

Keywords:

colorectal cancer cancer progression ezosomes molecular sygnatures lipidomics mass spectrometry

Descriptors:

  • NZ2_4:
  • NZ2_3:
  • NZ5_1:

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Anna Wojakowska 

Number of co-investigators in the project: 5

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 1 546 211 PLN

Project start date (Y-m-d): 2018-04-13

Project end date (Y-m-d): 2023-07-12

Project duration:: 63 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. Metabolome of Exosomes: Focus on Vesicles Released by Cancer Cells and Present in Human Body Fluids
    Authors:
    Aneta Zebrowska, Agata Skowronek, Anna Wojakowska, Piotr Widlak, Monika Pietrowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: Article Number: 3461), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20143461 - link to the publication
  2. Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy
    Authors:
    Wojakowska A, Marczak L, Zeman M, Chekan M, Zembala-Nożyńska E, Polanski K, Strugała A, Widlak P, Pietrowska M.
    Academic press:
    Frontiers in Oncology (rok: 2024, tom: 14, strony: 1323961), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fonc.2024.1323961 - link to the publication
  3. Molecular Composition of Serum Exosomes Could Discriminate Rectal Cancer Patients with Different Responses to Neoadjuvant Radiotherapy
    Authors:
    Urszula Strybel, Łukasz Marczak, Marcin Zeman, Krzysztof Polanski, Łukasz Mielańczyk, Olesya Klymenko, Anna Samelak-Czajka, Paulina Jackowiak, Mateusz Smolarz, Mykola Chekan, Ewa Zembala-Nożyńska, Piotr Widlak, Monika Pietrowska, Anna Wojakowska
    Academic press:
    Cancers (rok: 2022, tom: 14, strony: 993), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14040993 - link to the publication
  4. Metabolic Profiles of Whole Serum and Serum-Derived Exosomes Are Different in Head and Neck Cancer Patients Treated by Radiotherapy
    Authors:
    Anna Wojakowska , Aneta Zebrowska, Agata Skowronek, Tomasz Rutkowski, Krzysztof Polanski, Piotr Widlak, Lukasz Marczak, Monika Pietrowska
    Academic press:
    Journal of Personalized Medicine (rok: 2020, tom: 10, strony: 229), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm10040229 - link to the publication
  5. Metabolic Profiles of Whole Serum and Serum-Derived Exosomes Are Different in Head and Neck Cancer Patients Treated by Radiotherapy
    Authors:
    Anna Wojakowska , Aneta Zebrowska, Agata Skowronek, Tomasz Rutkowski, Krzysztof Polanski, Piotr Widlak, Lukasz Marczak, Monika Pietrowska
    Academic press:
    Journal of Personalized Medicine (rok: 2020, tom: 10, strony: 229), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm10040229 - link to the publication
  1. Proteomic profiles of small extracellular vesicles released by colon cancer cell line HCT116 with different p53 status
    Authors:
    Monika Pietrowska; Mateusz Smolarz; Marta Gawin; Urszula Strybel; Marek Rusin; Piotr Widlak; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (rok: 2022, ), Wydawca: Journal of Extracellular Vesicles/Wiley Online Library
    Data:
    konferencja 25-29.05.2022
    Status:
    Published
  2. Multi-omic approach for studying molecular components of serum-derived sEV andtumor tissue of rectal cancer patients with different response to neoadjuvant radiotherapy.
    Authors:
    Urszula Strybel; Lukasz Marczak; Marcin Zeman; Mykola Chekan; Ewa Zembala-Nozynska; ŁukaszMielanczyk; Monika Pietrowska; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (rok: 2022, ), Wydawca: Journal of Extracellular Vesicles/Wiley Online Library
    Data:
    konferencja 25-29.05.2022
    Status:
    Published
  3. Multi-omic approach for studying molecular components of serum-derived sEV andtumor tissue of rectal cancer patients with different response to neoadjuvant radiotherapy.
    Authors:
    Urszula Strybel; Lukasz Marczak; Marcin Zeman; Mykola Chekan; Ewa Zembala-Nozynska; ŁukaszMielanczyk; Monika Pietrowska; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (rok: 2022, ), Wydawca: Journal of Extracellular Vesicles/Wiley Online Library
    Data:
    konferencja 25-29.05.2022
    Status:
    Published
  4. Proteomic and metabolomic composition of serum-derived small extracellular vesiclescould discriminate rectal cancer patients with different responses to neoadjuvant radiotherapy
    Authors:
    Urszula Strybel; Lukasz Marczak; Marcin Zeman; Krzysztof Polanski; Łukasz Mielanczyk; Mateusz Smolarz; Piotr Widlak; MonikaPietrowska; Anna Wojakowska
    Conference:
    The ISEV2022 Annual Meeting (rok: 2022, ), Wydawca: Journal of Extracellular Vesicles/Wiley Online Library
    Data:
    konferencja 25-29.05.2022
    Status:
    Published