Projects funded by the NCN


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97 projects found matching your search criteria :

  1. DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr hab. Elżbieta Speina

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  2. Efficacy, toxicity and immunogenicity of carriers made of bioengineered spider silk for targeted drug delivery

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr hab. Hanna Dams-Kozłowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  3. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: dr hab. Robert Piotr Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  4. Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Tomasz Artur Stokłosa

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  5. Physicochemical characterization of cyclodextrins tailored for pH-dependent targeted therapy with anthracycline drugs

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Renata Bilewicz

    Uniwersytet Warszawski, Wydział Chemii

  6. Nanozeolites as a carriers of radium radionuclides in targeted therapy.

    Call: HARMONIA 1 , Panel: ST4

    Principal investigator: prof. Aleksander Józef Bilewicz

    Instytut Chemii i Techniki Jądrowej

  7. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms...

    Call: SONATA 1 , Panel: NZ4

    Principal investigator: dr Wojciech Stanisław Placha

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  8. New drug carriers in targeted anticancer therapy

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Artur Piotr Terzyk

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

  9. Nanoparticles of gold, gold-gold sulfide and titanium dioxide modified with tellurium as carriers for At-211 for targete...

    Call: OPUS 6 , Panel: ST4

    Principal investigator: prof. Aleksander Józef Bilewicz

    Instytut Chemii i Techniki Jądrowej

  10. BCL11b - Potential Therapeutic Target in T cell Neoplasms

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka Polskiej Akademii Nauk

  11. Cross-talk between PXR and AR receptors in hormone-dependent cancers.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Niemira

    Politechnika Gdańska, Wydział Chemiczny

  12. The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: prof. Joanna Benigna Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  13. Characteristics of the cell wall hydrolases of pathogenic bacteria Listeria monocytogenes and their partcipation in the ...

    Call: OPUS 5 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Anna Popowska

    Uniwersytet Warszawski, Wydział Biologii

  14. Cancer progression- the role of tumor-derived microfragments (oncosomes) as messangers in communication between tumor ce...

    Call: OPUS 4 , Panel: NZ6

    Principal investigator: dr Rafał Michał Szatanek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  15. DNA double-stranded break repair proteins as a target for personalized cancer therapy based on synthetic lethality

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  16. Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base...

    Call: SONATA 3 , Panel: NZ5

    Principal investigator: dr Paweł Wenancjusz Domagała

    Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

  17. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr Ewelina Zabost

    Uniwersytet Warszawski, Wydział Chemii

  18. Regulation of ALKBH proteins expression in cancer and its role in cancer therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: prof. Elżbieta Grzesiuk

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  19. Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t...

    Call: PRELUDIUM 2 , Panel: NZ1

    Principal investigator: dr Anna Stachurska

    Narodowy lnstytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy lnstytut Badawczy

  20. Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

    Call: SONATINA 9 , Panel: NZ6

    Principal investigator: dr Daria Nawrocka

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  21. The role of EZH2 activity in the development of resistance to targeted therapy in melanoma

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: dr Michał Jerzy Woźniak

    Uniwersytet Medyczny w Łodzi

  22. Janus nanoparticles - research on the effect of the duality of carriers of the activesubstance in targeted therapy of sk...

    Call: OPUS 28 , Panel: ST8

    Principal investigator: dr hab. Bożena Anna Tyliszczak

    Politechnika Krakowska im. Tadeusza Kościuszki

  23. M6A RNA methylation signatures as a targets for HPV-dependent HNSCC therapy

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: Kamila Ostrowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  24. Radiolabelled up-converting nanoparticles as theranostic agents for multimodal imaging and targeted therapy

    Call: SONATINA 8 , Panel: ST5

    Principal investigator: dr Karolina Kinga Zajdel

    Narodowe Centrum Badań Jądrowych

  25. Mitochondrial targets of flozins in endothelial cells - a new approach to the prevention, diagnosis and therapy of heart...

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr hab. Barbara Anna Kutryb-Zając

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  26. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  27. Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Anna Krętowska-Grunwald

    Uniwersytet Medyczny w Białymstoku

  28. Cuproptosis, a novel pathway of regulated cell death as a therapeutic target in treatment-naïve and targeted therapy-res...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: dr hab. Mariusz Łukasz Hartman

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  29. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Anna Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  30. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr hab. Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  31. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  32. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny

  33. Customized DNA-based nanocarriers to boost heart healing

    Call: WEAVE-UNISONO , Panel: NZ7

    Principal investigator: dr Monika Bzowska

    Uniwersytet Jagielloński

  34. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Teresa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  35. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  36. Modifiers of Muscleblind-like genes expression in health and disease.

    Call: SONATA BIS 12 , Panel: NZ5

    Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  37. Synthesis of new phthalocyanines for targeted photodynamic cancer therapy.

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Łukasz Andrzej Łapok

    Uniwersytet Jagielloński, Wydział Chemii; Zespół Nanotechnologii Polimerów i Biomateriałów

  38. Bioconjugates of 103Pd nanostructures for targeted Auger electron therapy.

    Call: OPUS 23 , Panel: ST5

    Principal investigator: dr hab. Agnieszka Majkowska-Pilip

    Instytut Chemii i Techniki Jądrowej

  39. Perinuclear AKAP6 signalosome as a new target for gene therapy in ischemic optic neuropathy

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: dr hab. Tomasz Boczek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  40. Interleukin-18 receptor targeted gene therapy as a novel approach for the treatment of pulmonary hypertension using cont...

    Call: POLONEZ BIS 1 , Panel: NZ5

    Principal investigator: dr Tara Scott

    Gdański Uniwersytet Medyczny

  41. The role of NPM1 as biomarker of the targeted therapy efficacy in chronic lymphocytic leukemia patients

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Krzysztof Georgios Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  42. Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Marek Arkadiusz Murias

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  43. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  44. Searching for new therapeutic targets in polyglutamine diseases

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr hab. Marta Olejniczak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  45. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  46. FGFR2-->JunB axis in progression of ER+ breast cancer - molecular analyses and prognostication

    Call: PRELUDIUM BIS 3 , Panel: NZ3

    Principal investigator: dr hab. Rafał Sebastian Sądej

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  47. Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

    Call: SONATA BIS 11 , Panel: NZ3

    Principal investigator: dr Karolina Szczepanowska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  48. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  49. Synthetic epidermal growth factor receptor inhibitor conjugated with nobel metal nanoparticles as a potential drug for t...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Shaoshan Mai

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  50. Bioconjugates of gold nanoparticles coated by 197/197mHg for Auger electron targeted therapy

    Call: PRELUDIUM 20 , Panel: ST5

    Principal investigator: Emilia Teresa Majka

    Instytut Chemii i Techniki Jądrowej