Projects funded by the NCN


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87 projects found matching your search criteria :

  1. DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

    Call: OPUS 8 , Panel: NZ5

    Principal investigator: dr hab. Elżbieta Speina

    Instytut Biochemii i Biofizyki PAN

  2. Efficacy, toxicity and immunogenicity of carriers made of bioengineered spider silk for targeted drug delivery

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr hab. Hanna Dams-Kozłowska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  3. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: dr hab. Robert Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  4. Identification of new, clinically relevant genetic and epigenetic aberrations by next-generation sequencing in chronic m...

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Tomasz Stokłosa

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  5. Physicochemical characterization of cyclodextrins tailored for pH-dependent targeted therapy with anthracycline drugs

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Renata Bilewicz

    Uniwersytet Warszawski, Wydział Chemii

  6. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms...

    Call: SONATA 1 , Panel: NZ4

    Principal investigator: dr Wojciech Placha

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

  7. New drug carriers in targeted anticancer therapy

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Artur Terzyk

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  8. Nanoparticles of gold, gold-gold sulfide and titanium dioxide modified with tellurium as carriers for At-211 for targete...

    Call: OPUS 6 , Panel: ST4

    Principal investigator: prof. Aleksander Bilewicz

    Instytut Chemii i Techniki Jądrowej

  9. BCL11b - Potential Therapeutic Target in T cell Neoplasms

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka PAN

  10. Cross-talk between PXR and AR receptors in hormone-dependent cancers.

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Niemira

    Politechnika Gdańska, Wydział Chemiczny

  11. The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: prof. Joanna Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  12. Characteristics of the cell wall hydrolases of pathogenic bacteria Listeria monocytogenes and their partcipation in the ...

    Call: OPUS 5 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Popowska

    Uniwersytet Warszawski, Wydział Biologii

  13. Cancer progression- the role of tumor-derived microfragments (oncosomes) as messangers in communication between tumor ce...

    Call: OPUS 4 , Panel: NZ6

    Principal investigator: dr Rafał Szatanek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

  14. DNA double-stranded break repair proteins as a target for personalized cancer therapy based on synthetic lethality

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  15. Nanozeolites as a carriers of radium radionuclides in targeted therapy.

    Call: HARMONIA 1 , Panel: ST4

    Principal investigator: prof. Aleksander Bilewicz

    Instytut Chemii i Techniki Jądrowej

  16. Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base...

    Call: SONATA 3 , Panel: NZ5

    Principal investigator: dr Paweł Domagała

    Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

  17. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr Ewelina Zabost

    Uniwersytet Warszawski, Wydział Chemii

  18. Regulation of ALKBH proteins expression in cancer and its role in cancer therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: prof. Elżbieta Grzesiuk

    Instytut Biochemii i Biofizyki PAN

  19. Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t...

    Call: PRELUDIUM 2 , Panel: NZ1

    Principal investigator: dr Anna Stachurska

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  20. Modulation of protein interaction networks as a new therapeutic target in the treatment of hereditary retinal dystrophie...

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Xiaonan Liu

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

  21. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  22. EBI2 receptor as a new myelin repair therapy in multiple sclerosis.

    Call: SONATA 18 , Panel: NZ3

    Principal investigator: dr Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Centrum Chorób Mózgu

  23. Targeted poloxamer micelles with selected drugs as a strategy for overcoming the mechanisms of multidrug resistance in p...

    Call: PRELUDIUM BIS 4 , Panel: NZ7

    Principal investigator: prof. Tomasz Gośliński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  24. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Piotrowska

    Warszawski Uniwersytet Medyczny

  25. Investigating the role of fibroblast growth factor receptors and STAT transcription factors in the targeted therapy of a...

    Call: PRELUDIUM BIS 4 , Panel: NZ5

    Principal investigator: prof. Ewa Marcinkowska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  26. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  27. Modifiers of Muscleblind-like genes expression in health and disease.

    Call: SONATA BIS 12 , Panel: NZ5

    Principal investigator: dr hab. Ewa Stępniak-Konieczna

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  28. Synthesis of new phthalocyanines for targeted photodynamic cancer therapy.

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Łukasz Łapok

    Uniwersytet Jagielloński, Wydział Chemii, Zespół Nanotechnologii Polimerów i Biomateriałów

  29. Bioconjugates of 103Pd nanostructures for targeted Auger electron therapy.

    Call: OPUS 23 , Panel: ST5

    Principal investigator: dr hab. Agnieszka Majkowska-Pilip

    Instytut Chemii i Techniki Jądrowej

  30. Perinuclear AKAP6 signalosome as a new target for gene therapy in ischemic optic neuropathy

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: dr hab. Tomasz Boczek

    Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

  31. Interleukin-18 receptor targeted gene therapy as a novel approach for the treatment of pulmonary hypertension using cont...

    Call: POLONEZ BIS 1 , Panel: NZ5

    Principal investigator: dr Tara Scott

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  32. The role of NPM1 as biomarker of the targeted therapy efficacy in chronic lymphocytic leukemia patients

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  33. Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Marek Murias

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  34. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  35. Searching for new therapeutic targets in polyglutamine diseases

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr hab. Marta Olejniczak

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  36. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  37. FGFR2-->JunB axis in progression of ER+ breast cancer - molecular analyses and prognostication

    Call: PRELUDIUM BIS 3 , Panel: NZ3

    Principal investigator: dr hab. Rafał Sądej

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  38. Proline metabolism as a novel therapeutic target for diseases associated with mitochondrial dysfunction.

    Call: SONATA BIS 11 , Panel: NZ3

    Principal investigator: dr Karolina Szczepanowska

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  39. Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr Jan Rodriguez Parkitna

    Instytut Farmakologii PAN

  40. Synthetic epidermal growth factor receptor inhibitor conjugated with nobel metal nanoparticles as a potential drug for t...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Shaoshan Mai

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  41. Bioconjugates of gold nanoparticles coated by 197/197mHg for Auger electron targeted therapy

    Call: PRELUDIUM 20 , Panel: ST5

    Principal investigator: Emilia Majka

    Instytut Chemii i Techniki Jądrowej

  42. In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Anna Pogorzelska

    Narodowy Instytut Leków

  43. Molecular and cellular landscape of pulmonary and hepatic metastases of colorectal cancer with potential clinical implic...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Marta Popęda

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  44. Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modi...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr hab. Tomasz Sarnowski

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  45. Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

    Call: PRELUDIUM BIS 2 , Panel: NZ6

    Principal investigator: dr hab. Magdalena Winiarska

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  46. Drug repurposing to target p53 protein family for improved therapy in the relapsed TP53 and EGFR mutated lung cancer

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Joanna Zawacka-Pankau

    Warszawski Uniwersytet Medyczny

  47. The use of surface proteins to capture cancer cells with functionalized magnetic nanoparticles as an innovative theranos...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr hab. Joanna Dulińska-Litewka

    Uniwersytet Jagielloński, Collegium Medicum

  48. Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies ...

    Call: OPUS 20 , Panel: NZ5

    Principal investigator: dr Natalia Bednarz-Knoll

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  49. On the way to elucidate the effects of cannabidiol (CBD) on living organisms - assessment of changes in the global trans...

    Call: PRELUDIUM BIS 2 , Panel: NZ9

    Principal investigator: dr hab. Artur Gurgul

    Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Ośrodek Medycyny Eksperymentalnej i Innowacyjnej

  50. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska