Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Cross-talk between PXR and AR receptors in hormone-dependent cancers.

2013/09/D/NZ7/04185

Keywords:

nuclear receptors targeted therapy hormone-dependent cancers metabolizing enzymes gene expression

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Politechnika Gdańska, Wydział Chemiczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Niemira 

Number of co-investigators in the project: 4

Call: SONATA 5 - announced on 2013-03-15

Amount awarded: 544 700 PLN

Project start date (Y-m-d): 2014-06-11

Project end date (Y-m-d): 2017-12-10

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Anticancer imidazoacridinone C-1311 is effective in androgen-dependent and androgen-independent prostate cancer cells
    Authors:
    Magdalena Niemira, Barbara Borowa-Mazgaj, Samuel B.Bader, Adrianna Moszyńska, Marcin Ratajewski, Kaja Karaś, Mirosław Kwaśniewski, Adam Krętowski, Zofia Mazerska, Ester M.Hammond, Anna Skwarska
    Academic press:
    Biomedicines (rok: 2020, tom: 8(9), strony: 45310), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biomedicines8090292 - link to the publication
  2. The role of androgen receptor and microRNA interactions in pathogenesis of androgen-dependent diseases.
    Authors:
    Agnieszka Bielska, Anna Skwarska, Adam Kretowski, Magdalena Niemira
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(3), strony: brak), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23031553 - link to the publication
  1. Integrative analysis of miRNA and mRNA paired expression profiling of androgen-dependent and -independent prostate cancer cells treated with anticancer imidazoacridinone C-1311.
    Authors:
    Niemira Magdalena, Bielska Agnieszka, Kwaśniewski Mirosław, Krętowski Adam, Skwarska Anna
    Conference:
    European Society of Human Genetics Conference (rok: 2019, ), Wydawca: European Journal of Human Genetics
    Data:
    konferencja 15-18.06.2019
    Status:
    Published
    DOI:
    link to the publication
  2. Transcriptional profiling reveals a potent activity of anticancer imidazoacridinone C-1311 against prostate cancer cells expressing androgen receptor
    Authors:
    Magdalena Niemira, Agnieszka Bielska, Zofia Mazerska, Mirosław Kwaśniewski, Adam Krętowski, Anna Skwarska
    Conference:
    European Society of Human Genetics Conference (rok: 2018, ), Wydawca: European Journal of Human Genetics
    Data:
    konferencja 16-19.06.2018
    Status:
    Published
    DOI:
    link to the publication

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