BCL11b - Potential Therapeutic Target in T cell Neoplasms
2013/09/B/NZ1/01867
Keywords
Descriptors
- NZ1_1: Biologia molekularna
- NZ1_5: Inżynieria genetyczna
Panel
NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution
Instytut Genetyki Człowieka PAN
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 5 – announced on 2013-03-15
- Amount awarded
- 676 000 PLN
- Project start date
- 2014-02-20
- Project end date
- 2017-12-19
- Project duration
- 46 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (5)
-
Novel targeted therapies of T cell lymphomas
- Authors:
- Iżykowska K, Rassek K, Korsak D, Przybylski GK.
- Academic press:
- Journal of Hematology and Oncology (year: 2020, volume: 13, pages: 176:1-38), Publisher: BioMed Central Ltd part of Springer Nature
- Status:
- Published
- DOI:
- 10.1186/s13045-020-01006-w – link to the publication
-
Mouse Models to Study Genes Involved in Hematological Malignancies
- Authors:
- Przybylski GK
- Academic press:
- Blood Science (year: 2020, volume: 2, pages: 50-53), Publisher: Wolters Kluwer / Lippincott Williams & Wilkins
- Status:
- Published
- DOI:
- 10.1097/BS9.0000000000000044 – link to the publication
-
Inhibition of BCL11B induces downregulation of PTK7 and results in growth retardation and apoptosis in T-cell acute lymphoblastic leukemia
- Authors:
- Li K, Chen C, Gao R, Yu X, Huang Y, Chen Z, Liu Z, Chen S, Luo G, Huang X, Przybylski GK, Li Y, Zeng C.
- Academic press:
- Biomarker Research (year: 2021, volume: 9, pages: 17:1-4), Publisher: BioMed Central Ltd part of Springer Nature
- Status:
- Published
- DOI:
- 10.1186/s40364-021-00270-3 – link to the publication
-
The N-terminal CCHC zinc finger motif mediates homodimerization of the transcription factor BCL11B
- Authors:
- Grabarczyk P, Winkler P, Delin M, Sappa PK, Bekeschus S, Hildebrandt P, Przybylski GK, Völker U, Hammer E, Schmidt CA
- Academic press:
- Molecular and Cellular Biology (year: 2018, volume: 38, pages: e00368-17), Publisher: American Society for Microbiology
- Status:
- Published
- DOI:
- 10.1128/MCB.00368-17 – link to the publication
-
Generation of Inducible BCL11B Knockout in TAL1/LMO1Transgenic Mouse T Cell Leukemia/Lymphoma Model
- Authors:
- Przybylski GK, Korsak D, Izykowska K, Nowicka K, Zalewski T, Tubacka M, Mosor M, Januszkiewicz-Lewandowska D, Frydrychowicz M, Boruczkowski M, Dworacki G, van den Brandt J, Grabarczyk P, Schmidt CA, Zeng C, Li Y
- Academic press:
- International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 4923: 1-10), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms23094932 – link to the publication