Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of innovative drug carriers and combination therapy

2021/41/N/NZ7/02530

Keywords:

doxorubicin triple-negative breast cancer breast cancer drug carrier combination therapy drug resistance

Descriptors:

  • NZ7_014:
  • NZ3_001:
  • NZ1_002:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Narodowy Instytut Leków

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Anna Karolina Pogorzelska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2022-01-10

Project end date (Y-m-d): 2026-01-09

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Antitumor and antimetastatic effects of dietary sulforaphane in a triple-negative breast cancer models
    Authors:
    A. Pogorzelska, M. Świtalska, J. Wietrzyk, M. Mazur, M. Milczarek, K. Medyńska, K. Wiktorska
    Academic press:
    Scientific reports (rok: 2024, tom: 14, strony: 16016), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-024-65455-w - link to the publication
  2. Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model
    Authors:
    Pogorzelska, A., Mazur, M., Świtalska, M., Wietrzyk, J., Sigorski, D., Fronczyk, K., Wiktorska, K.
    Academic press:
    Biomedicine & pharmacotherapy (rok: 2023, tom: 161, strony: 11), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2023.114490 - link to the publication
  3. Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model
    Authors:
    Pogorzelska, A., Mazur, M., Świtalska, M., Wietrzyk, J., Sigorski, D., Fronczyk, K., Wiktorska, K.
    Academic press:
    Biomedicine & pharmacotherapy (rok: 2023, tom: 161, strony: 11), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2023.114490 - link to the publication