Projects funded by the NCN

The stabilization mechanism and dissolution kinetics of co-amorphous systems - a new perspective on enhancing the effica...

Call: PRELUDIUM 24 , Panel: ST5

Principal investigator: Agata Olszewska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

"Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

New Insight into the Mechanism of Action of Antibiotic Peptides - The Role of the Electric Double Layer

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Sławomir Marcin Sęk

Uniwersytet Warszawski

Philosophical-logical foundations of mechanistic causation

Call: SONATINA 8 , Panel: HS1

Principal investigator: dr Michał Oleksowicz

Uniwersytet Mikołaja Kopernika

New insight into the mechanism of cytotoxic brain edema in acute liver failure: focus on the functionality of mitochondr...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Mariusz Paweł Popek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Cellular senescence as a new mechanism in development and progression of head and neck cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Michał Mateusz Masternak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Searching for new chemical compounds inducing resistance of apple to diseases and determination of the molecular mechani...

Call: SONATA 18 , Panel: NZ9

Principal investigator: dr Artur Mikiciński

Instytut Ogrodnictwa

Oncogene competition - a new interplay mechanism of mutant p53 with CMYC and mutant KRAS in human cancers.

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Dawid Włodzimierz Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi...

Call: OPUS 23 , Panel: NZ3

Principal investigator: dr Anna Marta Kulik

Instytut Biochemii i Biofizyki PAN

Development of a new laser materials used to giant pulse formation: Study of the loss control mechanism in Cr-doped garn...

Call: OPUS 23 , Panel: ST5

Principal investigator: Mykhailo Chaika

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Maciej Spiegel

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Farmaceutyczny

New mechanisms determining MFT-mediated sensitivity to abscisic acid during the germination of Medicago truncatula seeds

Call: OPUS 22 , Panel: NZ3

Principal investigator: dr Joanna Banasiak

Instytut Chemii Bioorganicznej PAN

The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in t...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Anna Janina Krasowska

Uniwersytet Wrocławski, Wydział Biotechnologii

Heart & brain interactions as a new approach to understanding the relationship between exercise and mood.

Call: SONATA 17 , Panel: HS6

Principal investigator: dr Tomasz Stanisław Ligęza

Uniwersytet Jagielloński, Wydział Filozoficzny

Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Mitochondria-targeting conjugates as a new anticancer agents

Call: OPUS 21 , Panel: ST4

Principal investigator: prof. Adam Włodzimierz Huczyński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Anna Staniak

Politechnika Warszawska, Wydział Chemiczny

A new class of antimicrobial compounds. Design, synthesis and study of the mechanism of action.

Call: PRELUDIUM BIS 2 , Panel: NZ7

Principal investigator: dr hab. Sylwia Anna Rodziewicz-Motowidło

Uniwersytet Gdański, Wydział Chemii

Semantics out of the grey box: How can representational mechanisms of the brain provide semantic properties of structura...

Call: PRELUDIUM BIS 2 , Panel: HS1

Principal investigator: dr hab. Marcin Tomasz Miłkowski

Instytut Filozofii i Socjologii Polskiej Akademii Nauk

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Anna Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

In search for new mechanisms of maize adaptation to cool spring conditions

Call: OPUS 20 , Panel: NZ9

Principal investigator: prof. Paweł Mieczysław Sowiński

Uniwersytet Warszawski, Wydział Biologii

Digital entrepreneurs and Industry 4.0. The key mechanism of the new path creation in the industrial regions?

Call: OPUS 20 , Panel: HS4

Principal investigator: dr hab. Krzysztof Gwosdz

Uniwersytet Jagielloński, Wydział Geografii i Geologii

A new approach to the development of a universal model of the gasochromic phenomenon based on a comprehensive analysis o...

Call: SONATA 16 , Panel: ST5

Principal investigator: dr hab. Michał Marek Mazur

Politechnika Wrocławska

New mechanisms regulating acetylcholine receptors at the neuromuscular junction

Call: OPUS 19 , Panel: NZ3

Principal investigator: dr hab. Tomasz Jacek Prószyński

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Qualified majorities in counter-majoritarian mechanisms: Towards a new theory of supermajorities in judicial review.

Call: POLS , Panel: HS5

Principal investigator: dr Mauro Arturo Rivera Leon

UNIWERSYTET ŚLĄSKI, Wydział Prawa i Administracji

Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

Call: SONATINA 4 , Panel: NZ1

Principal investigator: dr Aleksandra Anna Twarda-Cłapa

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

Analysis of bacteriophage P1 lytic functions as a way to discover the mechanisms of wide dissemination of clinical bacte...

Call: PRELUDIUM 18 , Panel: NZ6

Principal investigator: Agnieszka Bednarek

Instytut Biochemii i Biofizyki PAN

Metallofullerenols as a new generation of radioprotective agents – in vitro studies of radical processes in model biolog...

Call: SONATA 15 , Panel: ST4

Principal investigator: dr Jacek Bogdan Grębowski

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Toxicological features of new two-dimensional nanomaterials from the MBenes family

Call: OPUS 18 , Panel: ST5

Principal investigator: dr hab. Agnieszka Maria Jastrzębska

Politechnika Warszawska, Wydział Mechatroniki

Light-regulated mitochondrial potassium channels:searching for new cytoprotective mechanisms?

Call: MAESTRO 11 , Panel: NZ1

Principal investigator: prof. Adam Michał Szewczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to...

Call: OPUS 17 , Panel: NZ7

Principal investigator: prof. Zofia Mazerska

Politechnika Gdańska

Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

The combination of radiotherapy with imiquimod and sunitinib as a new therapeutic strategy overcoming some of the tumor ...

Call: SONATA 14 , Panel: NZ5

Principal investigator: dr Magdalena Jarosz-Biej

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Searching for new mechanisms of substance use or stress disoreders

Call: OPUS 15 , Panel: NZ7

Principal investigator: dr Wojciech Solecki

Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

Kinetics and mechanism of oxidation of new L12-strengthened cobalt-based superalloys modified with yttrium, zirconium an...

Call: PRELUDIUM 15 , Panel: ST8

Principal investigator: Damian Robert Migas

Politechnika Śląska

Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

New class of nucelus penetrating peptides. Design, synthesis and mechanism of action

Call: OPUS 14 , Panel: ST5

Principal investigator: dr hab. Magdalena Wysocka

Uniwersytet Gdański, Wydział Chemii

Towards New Metal Alkoxides and Alkylperoxides: Contrasting Oxygenation vs Protonolysis Reactions of the Respective Orga...

Call: OPUS 14 , Panel: ST5

Principal investigator: prof. Janusz Zbigniew Lewiński

Politechnika Warszawska, Wydział Chemiczny

Studies of alkylation mechanism of DNA oligomers using new Top I inhibitors from camptothecin family by physical organic...

Call: OPUS 14 , Panel: ST4

Principal investigator: prof. Lech Jan Kozerski

Narodowy Instytut Leków

New proton conducting composites of nanocrystalline cellulose doped by nitrogen-containing heterocyclic molecules: from ...

Call: OPUS 13 , Panel: ST8

Principal investigator: prof. Jadwiga Maria Tritt-Goc

Instytut Fizyki Molekularnej PAN

The mechanism and kinetics of rehydroxylation in calcined clay minerals as a key to a new method of archaeological datin...

Call: OPUS 13 , Panel: ST10

Principal investigator: dr hab. Arkadiusz Derkowski

Instytut Nauk Geologicznych, Polska Akademia Nauk, Ośrodek Badawczy w Krakowie

Evaluation of anticancer properties and molecular mechanisms of action of new hybrid molecules containing uracil skeleto...

Call: PRELUDIUM 13 , Panel: NZ3

Principal investigator: dr Angelika Agata Długosz-Pokorska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Investigations of the properties of composites with addition of the new family of 2D crystals

Call: OPUS 13 , Panel: ST8

Principal investigator: dr hab. Andrzej Roman Olszyna

Politechnika Warszawska, Wydział Inżynierii Materiałowej

Design of new small molecular regulators (inhibitors, activators) of the catalytic activity of adenylate kinases. Molecu...

Call: OPUS 13 , Panel: ST4

Principal investigator: dr Anna Kozakiewicz-Piekarz

Uniwersytet Mikołaja Kopernika, Wydział Chemii

New semiconductor materials for photocatalytic hydrogen generation: mechanism formation in the presence of ionic liquids

Call: OPUS 13 , Panel: ST8

Principal investigator: dr hab. Ewelina Grabowska-Musiał

Uniwersytet Gdański, Wydział Chemii

Neuromedin U, new potential regulator of colorectal cancer metastasis mechanisms.

Call: SONATA BIS 6 , Panel: NZ3

Principal investigator: dr Patrycja Justyna Przygodzka

Instytut Biologii Medycznej PAN

Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

Call: SONATA 11 , Panel: NZ7

Principal investigator: dr Anna Woziwodzka

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Krzysztof Zdzisław Walczak

Politechnika Śląska, Wydział Chemiczny