Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From molecular mechanistic insight in model systems to new therapeutic targets.

2019/35/B/ST4/04266

Keywords:

nitric oxide redox thiols switches metal ions and compounds cell signalling kinetics mechanisms catalytic processes age related disorders

Descriptors:

  • ST4_009:
  • ST4_017:
  • ST4_014:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Grażyna Jolanta Stochel 

Number of co-investigators in the project: 17

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 996 212 PLN

Project start date (Y-m-d): 2020-07-06

Project end date (Y-m-d): 2025-12-05

Project duration:: 65 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (11)
  • Book publications / chapters in book publications (2)
  1. Investigation of the Immunogenic Properties of Ovalbumin Modified by Urban Airborne Particulate Matter
    Authors:
    B. Nowak, A. Wądołek, O. Mazuryk, A. Poznańska, K. Majzner, G. Majka, M. Oszajca, M. Barańska, G. Stochel, J. Marcinkiewicz
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2023, tom: 71, art. 13, strony: 45671), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-023-00679-8 - link to the publication
  2. A Personal Account on Inorganic Reaction Mechanisms
    Authors:
    J. Polaczek, K. Kieca, M. Oszajca, O. Impert, A. Katafias, D. Chatterjee, D. Ćoćić, R. Puchta, G. Stochel, C.D. Hubbard, R. van Eldik
    Academic press:
    THE CHEMICAL RECORD (rok: 2023, tom: 23, art. e202300278, strony: 45688), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/tcr.202300278 - link to the publication
  3. Unraveling the molecular mechanism of S-nitrosation mediated by N-acetylmicroperoxidase-11
    Authors:
    M. Oszajca, A. Jodłowska, D. Rutkowska-Zbik, K. Kieca, G. Stochel
    Academic press:
    Inorganic Chemistry (rok: 2023, tom: 62, strony: 5630–5643), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.3c00180 - link to the publication
  4. Blood Plasma's Protective Ability against the Degradation of S-Nitrosoglutathione under the Influence of Air-Pollution-Derived Metal Ions in Patients with Exacerbation of Heart Failure and Coronary Artery Disease
    Authors:
    Anna Wądołek, Dominika Drwiła, Maria Oszajca, Grażyna Stochel, Ewa Konduracka, Małgorzata Brindell
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22 art. 10500, strony: 45676), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221910500 - link to the publication
  5. Ligand-Tuning of the Stability of Pd(II) Conjugates with Cyanocobalamin
    Authors:
    Dominika Porębska, Łukasz Orzeł, Dorota Rutkowska-Zbik, Grażyna Stochel, Rudi van Eldik
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22, art. 7973, strony: 45673), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22157973 - link to the publication
  6. Enhancement of NO release from S-nitrosoalbumin by pollution derived metal ions
    Authors:
    Anna Wądołek, Maria Oszajca, Wiktoria Pęcak, Małgorzata Brindell, Grażyna Stochel
    Academic press:
    Dalton Transaction (rok: 2021, tom: 50, strony: 9923-9933), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d1dt01260f - link to the publication
  7. Nitric Oxide Signaling and Sensing in Age-Related Diseases
    Authors:
    1. O. Mazuryk, I. Gurgul, M. Oszajca, J. Polaczek, K. Kieca, E. Bieszczad-Żak, T. Martyka, G. Stochel
    Academic press:
    Antioxidants (rok: 2024, tom: 13 art. 1213, strony: 14246), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox13101213 - link to the publication
  8. High-Pressure Mechanistic Insight into Bioinorganic NO Chemistry
    Authors:
    Łukasz Orzeł, Maria Oszajca, Justyna Polaczek, Dominika Porębska, Rudi van Eldik, Grażyna Stochel
    Academic press:
    Molecules (rok: 2021, tom: 26 art. 4947, strony: 45681), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26164947 - link to the publication
  9. Blood Plasma's Protective Ability against the Degradation of S-Nitrosoglutathione under the Influence of Air-Pollution-Derived Metal Ions in Patients with Exacerbation of Heart Failure and Coronary Artery Disease
    Authors:
    Anna Wądołek, Dominika Drwiła, Maria Oszajca, Grażyna Stochel, Ewa Konduracka, Małgorzata Brindell
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22 art. 10500, strony: 45676), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221910500 - link to the publication
  10. Synthesis and characterization of cyanocobalamin conjugates with Pt(II) complexes towards potential therapeutic applications
    Authors:
    D. Porębska, Ł. Orzeł, D. Rutkowska-Żbik, G. Stochel, R. van Eldik
    Academic press:
    Polyhedron (rok: 2023, tom: 230 art. 116230, strony: 45666), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.poly.2022.116230 - link to the publication
  11. Unraveling the molecular mechanism of S-nitrosation mediated by N-acetylmicroperoxidase-11
    Authors:
    M. Oszajca, A. Jodłowska, D. Rutkowska-Zbik, K. Kieca, G. Stochel
    Academic press:
    Inorganic Chemistry (rok: 2023, tom: 62, strony: 5630–5643), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.inorgchem.3c00180 - link to the publication
  1. Mechanistic insight into photoactivation of small inorganic molecules from the biomedical application perspectives
    Authors:
    1. A. Kyzioł, Ł. Orzeł, I. Gurgul, O. Mazuryk, P. Łabuz, G. Stochel
    Book:
    Advances in Inorganic Chemistry (rok: 2022, tom: vol. 80, Biomedical Applications of Inorganic Photochemistry, strony: 233-284), Wydawca: Elsevier, Academic Press
    Status:
    Published
    DOI:
    10.1016/S0898-8838(22)00043-5 - link to the publication
  2. Mechanistic insight into photoactivation of small inorganic molecules from the biomedical application perspectives
    Authors:
    1. A. Kyzioł, Ł. Orzeł, I. Gurgul, O. Mazuryk, P. Łabuz, G. Stochel
    Book:
    Advances in Inorganic Chemistry (rok: 2022, tom: vol. 80, Biomedical Applications of Inorganic Photochemistry, strony: 233-284), Wydawca: Elsevier, Academic Press
    Status:
    Published
    DOI:
    10.1016/S0898-8838(22)00043-5 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy