Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor for Endocytosis, stabilin-2.

2020/36/C/NZ1/00095

Keywords:

hyaluronic acid receptor HARE stabilin-2 protein-ligand interactions scavenger receptor oligonucleotides advanced glycation end products diabetes X-ray crystallography

Descriptors:

  • NZ1_001:
  • NZ1_004:
  • NZ1_002:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aleksandra Anna Twarda-Cłapa 

Number of co-investigators in the project: 1

Call: SONATINA 4 - announced on 2019-12-16

Amount awarded: 794 304 PLN

Project start date (Y-m-d): 2020-10-02

Project end date (Y-m-d): 2025-10-01

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. An update patent review of MDM2–p53 interaction inhibitors (2019–2023)
    Authors:
    Aleksandra Twarda-Clapa
    Academic press:
    Expert Opinion on Therapeutic Patents (rok: 2024, tom: 34 (12), strony: 1177-1198), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/13543776.2024.2419836 - link to the publication
  2. Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs
    Authors:
    Twarda-Clapa, A.; Olczak, A.; Białkowska, A.M.; Koziołkiewicz, M.
    Academic press:
    Cells (rok: 2022, tom: 11, strony: 1312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11081312 - link to the publication
  3. Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs
    Authors:
    Twarda-Clapa, A.; Olczak, A.; Białkowska, A.M.; Koziołkiewicz, M.
    Academic press:
    Cells (rok: 2022, tom: 11, strony: 1312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11081312 - link to the publication