Projects funded by the NCN
The role of Candida albicans' plasma membrane sphingolipids in the potentially new mechanism of drug resistance and in the inflammatory response
2021/43/B/NZ1/00523
Keywords:
Candida albicans sphingolipids ergosterol drug resistance inflammatory response
Descriptors:
- NZ1_010:
- NZ1_001:
- NZ1_011:
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Wrocławski, Wydział Biotechnologii
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 22 - announced on 2021-09-15
Amount awarded: 1 628 700 PLN
Project start date (Y-m-d): 2022-07-21
Project end date (Y-m-d): 2026-07-20
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Alterations in the level of ergosterol in Candida albicans' plasma membrane correspond with changes in virulence and result in triggering diversed inflammatory responseAuthors:Derkacz D. and Krasowska AAcademic press:International Journal of Molecular Sciences (rok: 2023, tom: 24, strony: 3966-3982), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms24043966 - link to the publication
- The Role of Ergosterol and Sphingolipids in the Localization and Activity of Candida albicans' Multidrug Transporter Cdr1p and Plasma Membrane ATPase Pma1pAuthors:Urbanek Aneta, Muraszko Jakub, Derkacz Daria, Łukaszewicz Marcin, Bernat Przemysław, Krasowska AnnaAcademic press:International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 9975 - 9992), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms23179975 - link to the publication