Projects funded by the NCN
Analysis of bacteriophage P1 lytic functions as a way to discover the mechanisms of wide dissemination of clinical bacterial strains carrying P1 derivatives with genes encoding resistance to new generation beta-lactam antibiotics
2019/35/N/NZ6/03789
Keywords:
bacteriophage P1 enterobacteria resistance to new-generation beta-lactams mechanisms of bacteriophage-mediated lysis of bacteria horizontal gene transfer bacteriophages of wide host-range
Descriptors:
- NZ6_004:
- NZ6_008:
- NZ2_001:
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Instytut Biochemii i Biofizyki Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 18 - announced on 2019-09-16
Amount awarded: 139 920 PLN
Project start date (Y-m-d): 2020-06-25
Project end date (Y-m-d): 2022-12-24
Project duration:: 30 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Efficient, traceless modification of the P1 bacteriophage genome through homologous recombination with enrichment in double recombinants: A new perspective on the functional annotation of uncharacterized phage genesAuthors:Agnieszka Bednarek, Katarzyna Giermasińska-Buczek, Małgorzata ŁobockaAcademic press:Frontiers in Microbiology (rok: 2023, tom: 14, strony: 6), Wydawca: FrontiersStatus:Accepted for publicationDOI:10.3389/fmicb.2023.1135870 - link to the publication
- Functional Dissection of P1 Bacteriophage Holin-like Proteins Reveals the Biological Sense of P1 Lytic System ComplexityAuthors:Agnieszka Bednarek, Agata Cena, Wioleta Izak, Joanna Bigos, Małgorzata ŁobockaAcademic press:International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 20), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms23084231 - link to the publication