Projects funded by the NCN


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234 projects found matching your search criteria :

  1. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Marta Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  2. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Alicja Aleksandra Gawalska

    Uniwersytet Jagielloński, Collegium Medicum

  3. Interconversions of supramolecular architectures based on Schiff base ligands and transition metal ions as potential pro...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Martyna Szymańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  4. Structure-function relationship in fibroblast growth factor signaling

    Call: CEUS-UNISONO , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  5. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii PAN

  6. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  7. Role of the Intersubunit and Interdomain Interactions in the GABAA Receptor Modulation by Protons.

    Call: ETIUDA 8 , Panel: NZ1

    Principal investigator: Michał Adam Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  8. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Anna Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  9. Do potential new MRGPRX2 ligands induce mastocytes degranulation in human?

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Grzegorz Porębski

    Uniwersytet Jagielloński, Collegium Medicum

  10. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  11. MXO2-ISOMER: in search of colour-changing photoswitchable materials based on 4th-row transition-metal complexes with sim...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Natalia Jarzembska

    Uniwersytet Warszawski, Wydział Chemii

  12. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Urszula Karaś

    Instytut Biologii Medycznej PAN

  13. Analysis of the conformations of organic compounds in macromolecular structures

    Call: PRELUDIUM 18 , Panel: ST6

    Principal investigator: Joanna Magdalena Macnar

    Uniwersytet Warszawski, Wydział Chemii

  14. In search of new metalloporphyrinoid catalysts for functionalization of C(sp3)-H bonds

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr Karolina Dorota Hurej

    Uniwersytet Wrocławski, Wydział Chemii

  15. Bioconjugates labeled with alpha- and beta-particle emitting radionuclides as potential radiopharmaceuticals in Targeted...

    Call: SONATA BIS 9 , Panel: ST4

    Principal investigator: dr hab. Marek Pruszyński

    Instytut Chemii i Techniki Jądrowej

  16. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm...

    Call: SONATA BIS 9 , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  17. Study on the structure related dielectric properties and molecular dynamics of poly(dimethylsiloxane) crosslinked by met...

    Call: PRELUDIUM 17 , Panel: ST3

    Principal investigator: Angelika Kinga Wrzesińska

    Politechnika Łódzka, Wydział Chemiczny

  18. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur...

    Call: PRELUDIUM 17 , Panel: NZ7

    Principal investigator: Marcin Józef Drop

    Uniwersytet Jagielloński, Collegium Medicum

  19. Therapeutic potential of biased 5-HT7 receptor ligands in the treatment of depression

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: prof. Paweł Maria Zajdel

    Uniwersytet Jagielloński, Collegium Medicum

  20. Synteza nowych funkcjonalnych układów metalosupramolekularnych na bazie ligandów ambidentnych i jonów metali d elektrono...

    Call: ETIUDA 7 , Panel: ST4

    Principal investigator: Anna Maria Walczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  21. Development of new and more efficient treatment against mesothelioma utilizing oncolytic adenovirus armed with ICOS liga...

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

  22. Rational design and evaluation of functionally biased opioid agonists

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  23. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  24. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Artur Wnorowski

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

  25. Synthesis and physicochemical properties of novel functional metal-organic compounds based on hypophosphite ligands

    Call: OPUS 16 , Panel: ST5

    Principal investigator: prof. Mirosław Robert Mączka

    Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

  26. Epigenomic, immunogenetic and proteomic strategies for identification of NK cell determinants of prognostic value for pa...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: prof. Katarzyna Maria Bogunia-Kubik

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  27. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  28. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  29. Searching for mu opioid receptor peptide agonists with G protein/beta-arrestin biased profile and their pharmacological ...

    Call: SONATA 14 , Panel: ST5

    Principal investigator: dr Justyna Piekielna-Ciesielska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  30. Novel hybrid 5-HT6 serotonin receptor and SERT transporter ligands as a therapeutic perspective of behavioural and cogni...

    Call: SONATA 14 , Panel: NZ7

    Principal investigator: dr Agata Siwek

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  31. Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li...

    Call: SONATA BIS 8 , Panel: ST4

    Principal investigator: dr Sergey Samsonov

    Uniwersytet Gdański, Wydział Chemii

  32. Molecular basis of host specificity of Laverania parasites

    Call: HARMONIA 10 , Panel: NZ6

    Principal investigator: dr hab. Ewa Katarzyna Jaśkiewicz

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  33. Towards novel ZnO quantum dots coated with mixed-ligand shell

    Call: PRELUDIUM 15 , Panel: ST5

    Principal investigator: Anna Natalia Wojewódzka

    Politechnika Warszawska, Wydział Chemiczny

  34. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii PAN

  35. Multifunctional ligands - TRPA1 channel antagonists and phosphodiesterases inhibitors as a new approach for the treatmen...

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Grażyna Chłoń-Rzepa

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  36. Development of a group of non-basic ligands of serotonin receptor 5-HT7, derivatives of 2-(6-oxo-3-phenyl-1,6-dihydropyr...

    Call: SONATINA 2 , Panel: NZ7

    Principal investigator: dr Sabina Marta Podlewska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  37. Diet and human gut microbiome as sources of N-acyl amines acting as GPCR ligands.

    Call: SONATINA 2 , Panel: NZ9

    Principal investigator: dr Anna Katarzyna Drzazga

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  38. NCN-cyklometalujące ligandy pirenowe oraz ligandy tridentne w syntezie mono- i binuklearnych związków kompleksowych

    Call: ETIUDA 6 , Panel: ST5

    Principal investigator: Dawid Mariusz Zych

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

  39. Synthesis of ruthenium complexes bearing CAAC ligands and their use in metathesis reactions

    Call: OPUS 14 , Panel: ST5

    Principal investigator: dr hab. Anna Kajetanowicz

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  40. The effect of peroxisome proliferator-activated receptor gamma (PPARy) ligands on the transrciptome and proteome profile...

    Call: PRELUDIUM 14 , Panel: NZ9

    Principal investigator: Zuzanna Kunicka

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

  41. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  42. Mechanisms of binding and transport in plasma of amyloid beta oligomers by human serum albumin (HSA) in presence of sele...

    Call: OPUS 14 , Panel: ST4

    Principal investigator: prof. Maciej Leszek Kozak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  43. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death...

    Call: MAESTRO 9 , Panel: ST5

    Principal investigator: prof. Tadeusz Andrzej Holak

    Uniwersytet Jagielloński, Wydział Chemii

  44. Enlarged aceneporphyrinoids - multitopic ligands with tunable binding properties

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Bartosz Szyszko

    Uniwersytet Wrocławski, Wydział Chemii

  45. Predicting affinity of ligands to RNA. The case of an aminoglycoside-sensing riboswitch.

    Call: HARMONIA 9 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  46. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  47. Intracellular cross-talk between ligands and Notch receptors determine signalling response

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: prof. Adolfo Rivero-Muller

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  48. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i...

    Call: PRELUDIUM 13 , Panel: NZ7

    Principal investigator: dr Agnieszka Wioleta Jankowska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  49. Novel ligands of histamine receptor H4 as potential anti-allergic and anti-inflammatory drugs

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  50. From novel rhenium(I) complexes with triimine ligands towards more efficient photo- and electroluminescence materials

    Call: OPUS 13 , Panel: ST5

    Principal investigator: prof. Barbara Elżbieta Machura

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych