Projects funded by the NCN
New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of glioblastoma multiforme.
2020/37/N/NZ7/02120
Keywords:
5-HT6 serotonin glioblastoma synthesis microwave sonochemistry molecular modeling low-base ligands sulfonamides guanidines
Descriptors:
- NZ7_014:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 19 - announced on 2020-03-16
Amount awarded: 209 880 PLN
Project start date (Y-m-d): 2021-03-26
Project end date (Y-m-d): 2024-03-25
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Eco-friendly methods of synthesis and preliminary biological evaluation of sulfonamide derivatives of cyclic arylguanidinesAuthors:Przemysław Zaręba, Anna K. Drabczyk, Artur Wnorowski, Edyta Pindelska, Gniewomir Latacz, Jolanta JaśkowskaAcademic press:Ultrasonics Sonochemistry (rok: 2022, tom: 90, strony: 106165), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ultsonch.2022.106165 - link to the publication