Projects funded by the NCN
Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds
2019/35/N/NZ7/04258
Keywords:
CB1 CB2 CB1 receptor CB2 receptor cannabinoids endocannabinoid system GPCR docking molecular dynamics computer simulations protein-ligand interactions
Descriptors:
- NZ7_014:
- NZ1_003:
- ST4_004:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 18 - announced on 2019-09-16
Amount awarded: 138 360 PLN
Project start date (Y-m-d): 2020-07-20
Project end date (Y-m-d): 2022-12-19
Project duration:: 29 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Identification of Novel CB2 Ligands through Virtual Screening and In Vitro EvaluationAuthors:Adam Stasiulewicz, Anna Lesniak, Magdalena Bujalska-Zadrożny, Tomasz Pawiński, Joanna I. SulkowskaAcademic press:Journal of Chemical Information and Modeling (rok: 2023, tom: 63, strony: 1012-1027), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acs.jcim.2c01503 - link to the publication
- Identification of CB1 Ligands among Drugs, Phytochemicals and Natural-Like Compounds: Virtual Screening and In Vitro VerificationAuthors:Adam Stasiulewicz, Anna Lesniak, Piotr Setny, Magdalena Bujalska-Zadrożny, Joanna I. SulkowskaAcademic press:ACS Chemical Neuroscience (rok: 2022, tom: 13, strony: 2991–3007), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acschemneuro.2c00502 - link to the publication