Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

2018/31/D/NZ7/01350

Keywords:

biased signaling pharmacology of G protein-coupled receptors

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Artur Wnorowski 

Number of co-investigators in the project: 2

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 1 114 722 PLN

Project start date (Y-m-d): 2019-09-30

Project end date (Y-m-d): 2024-09-29

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist.
    Authors:
    Artur Wnorowski, Danuta Dudzik, Michel Bernier, Jakub Wójcik, Guido Keijzers, Alberto Diaz-Ruiz, Karolina Mazur, Yongqing Zhang, Haiyong Han, Morten Scheibye‑Knudsen, Krzysztof Jóźwiak, Coral Barbas, Irving W. Wainer.
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: [art. nr] 3618, s. 1-19,), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-07600-x - link to the publication
  2. Gene Expression Data Mining Reveals the Involvement of GPR55 and Its Endogenous Ligands in Immune Response, Cancer, and Differentiation
    Authors:
    Artur Wnorowski, Jakub Wójcik, Maciej Maj
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 13328), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222413328 - link to the publication

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