Projects funded by the NCN

The effect of omega-3 polyunsaturated acids supplementation on endothelial function, oxidative stress, platelet aggregat...

Call: OPUS 2 , Panel: NZ5

Principal investigator: dr hab. Grzegorz Paweł Gajos

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Heart Failure-Induced Alterations in Platelet Phenotype: Impact on Lung Microvascular Endothelial Barrier Integrity.

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Mohammadebrahim Hosseinzadehmaleki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Endothelial bioenergetics as a novel target for vascular protection – unveiling the mitochondrial mechanisms of lipid-lo...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: dr Alicja Małgorzata Braczko

Gdański Uniwersytet Medyczny, Wydział Lekarski

The Role of the Mitochondrial Unfolded Protein Response (UPRmt) in Endothelial Function: a Possible Novel Target for the...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Sylwester Tycjan Mosiołek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Cross-talk between endothelium and perivascular adipose tissue upon inflammation: high-resolution imaging of adipocytes ...

Call: PRELUDIUM 22 , Panel: ST4

Principal investigator: Ewa Stanek

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Participation of exosomes secreted by neutrophils in the modulation of angiogenesis - the role of the type 1 interferon ...

Call: SONATINA 7 , Panel: NZ5

Principal investigator: dr Mateusz Piotr Smolarz

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach

Impact of uremic carbamylation on RAA system and endothelial dysfunction

Call: OPUS 24 , Panel: NZ4

Principal investigator: prof. Piotr Mydel

Uniwersytet Jagielloński

Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in...

Call: POLONEZ BIS 3 , Panel: NZ7

Principal investigator: dr hab. Aneta Iwona Radziwon-Balicka

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

Call: PRELUDIUM BIS 4 , Panel: NZ6

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The impact of physical activity on brain resilience to chronic stress and the mediating role of blood-brain barrier.

Call: OPUS 24 , Panel: NZ7

Principal investigator: dr Marta Maria Nowacka-Chmielewska

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

Porous materials produced from ice templates dedicated to endothelial-muscle cell coculture

Call: PRELUDIUM BIS 4 , Panel: ST5

Principal investigator: dr hab. Roman Major

Instytut Metalurgii i Inżynierii Materiałowej im. Aleksandra Krupkowskiego Polskiej Akademii Nauk

In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Róża Kij

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assessment of the susceptibility of the lung endothelium to infections with respiratory viruses and its involvement ...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Maciej Zygmunt Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Keap1-dependent proteopathy as a unifying mechanism of vascular dysfunction

Call: OPUS 22 , Panel: NZ4

Principal investigator: dr hab. Anna Maria Grochot-Przęczek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Role of endothelial cells in development of post-inflammatory dilated cardiomyopathy

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: dr hab. Przemysław Jerzy Błyszczuk

Uniwersytet Jagielloński, Collegium Medicum

Multimodal approach for a comprehensive assessment of (dys)functional endothelial phenotype in isolated blood vessels

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Zofia Pacia

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Metabolic reprogramming in age-dependent endothelial dysfunction and vascular stiffness; novel mechanism of inflamm-agei...

Call: MAESTRO 13 , Panel: NZ4

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

How mutations in the dystrophin-encoding gene affect calcium homeostasis, energy metabolism and selected functions of va...

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Krzysztof Olaf Zabłocki

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

PDMS-based specially designed microfluidic channel lined with primary endothelial cells: a novel tool for experimental p...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Stefano Rocchetti

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Assessment of the endothelial adherens junctions, neuronal damage and the fetal blood-brain barrier integrity in respons...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Natalia Barbara Misan

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of rhinovirus in the limitation of infection of the human lung endothelium with low pathogenic coronavirus in t...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Mateusz Gawrysiak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Breast cancer metastasis-induced endothelial-mesenchymal transition alongside ageing; implications for therapy

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Marta Maria Smęda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Early and late consequences of stem cell compartment damage due to SARS-CoV-2 infection

Call: OPUS 21 , Panel: NZ6

Principal investigator: prof. Magdalena Józefa Kucia

Warszawski Uniwersytet Medyczny

The role of lactate dehydrogenase A in development of endothelial dysfunction in murine model of heart failure

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Agnieszka Karolina Karaś

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera...

Call: CHIST-ERA2020 , Panel: NZ7

Principal investigator: prof. Stefan Karol Chłopicki

Uniwersytet Jagielloński

Enhancement of heart repair after myocardial infarction by means of genetically improved cardiomyocytes and endothelial ...

Call: SHENG 2 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

Importance of fatty acids and their transporters for placenta development in the pig

Call: OPUS 20 , Panel: NZ9

Principal investigator: prof. Agnieszka Blitek

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

Identify molecules and mechanisms by which all-trans retinoic acid-induced browning of perivascular adipose tissue regul...

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Małgorzata Barbara Kalisz

Centrum Medyczne Kształcenia Podyplomowego

LDL-mimetic liposomal contrast agent for MRI-based detection of increased endothelial permeability in the early phase of...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Anna Bar

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Vascular endothelium-supporting materials: Understanding the structural and physicochemical requirements

Call: OPUS 20 (LAP) , Panel: ST5

Principal investigator: prof. Tomasz Ciach

Politechnika Warszawska

Microenvironment in differentiation and maturation of human pancreatic endocrine cells

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr hab. Małgorzata Borowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Molecular background of microvascular complications in HNF1A-MODY patients: induced pluripotent stem cells as disease mo...

Call: SONATA BIS 10 , Panel: NZ3

Principal investigator: dr Neli Metodieva Kachamakova-Trojanowska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Spectroscopic and microscopic techniques in nano-probing, modeling and recognition of interactions between erythrocytes ...

Call: SONATA BIS 10 , Panel: ST4

Principal investigator: dr hab. Katarzyna Maria Marzec

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Fizyki i Informatyki Stosowanej

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Agata Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The proangiogenic functions of PIM kinases in plasma cell myeloma

Call: ETIUDA 8 , Panel: NZ5

Principal investigator: Filip Aleksander Garbicz

Instytut Hematologii i Transfuzjologii

Which patients with rheumatoid arthritis or axial spondyloarthritis without classical cardiovascular risk factors have m...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Jarosław Łukasz Nowakowski

Uniwersytet Jagielloński, Collegium Medicum

Gamma-glutamylcysteine ligase participation in the antioxidant mechanism of action of sulodexide on vascular endothelial...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Klaudia Katarzyna Bontor

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

DHA/EPA and changes of peripheral blood cell epigenetics as well as the level of endothelial and pancreatic beta cell sp...

Call: MAESTRO 1 , Panel: NZ2

Principal investigator: prof. Aldona Magdalena Dembińska-Kieć

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydzial Lekarski

In search of spectroscopic markers of autophagy based on pharmacologically induced phospholipidosis in endothelial cells

Call: PRELUDIUM 18 , Panel: ST4

Principal investigator: Ewelina Joanna Bik

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The effect of anoxia/reoxygenation on the bioenergetic properties of mitochondria isolated from endothelial cells cultur...

Call: PRELUDIUM 18 , Panel: NZ1

Principal investigator: Karolina Katarzyna Dominiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Function and phenotype of liver sinusoidal endothelial cells (LSECs) and their role in liver dysfunction development in ...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Kamila Wojnar-Lasoń

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

From the structure of fenestrations in live Liver Sinusoidal Endothelial Cells to real-time in vitro pharmacology

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr hab. Bartłomiej Zapotoczny

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Barbara Anna Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

Call: PRELUDIUM 17 , Panel: NZ5

Principal investigator: Brygida Elżbieta Marczyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Quantitative assessment of vascular endothelial growth factor (VEGF) in serum, follicular fluid (FF) and VEGF mRNA in gr...

Call: OPUS 1 , Panel: NZ5

Principal investigator: prof. Artur Jacek Jakimiuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

The assessment of cysteinyl leukotriene receptor antagonist role in inhibition of atherosclerosis, proliferation and its...

Call: OPUS 17 , Panel: NZ5

Principal investigator: dr hab. Paweł Maga

Uniwersytet Jagielloński, Collegium Medicum

The role of molecular composition of endothelial and pancreatic beta-cell extracellular vesicle in diabetic endothelial ...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Ewa Łucja Stępień

Uniwersytet Jagielloński

Cellular mechanisms and effects in vivo of selective lactate dehydrogenase A inhibitors in experimental models of mesoth...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Godefridus J Peters

Gdański Uniwersytet Medyczny, Wydział Lekarski

Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electroph...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Karolina Martyna Matyjaszczyk-Gwarda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Ectosomal alpha-v beta-3 and alpha-v beta-5 as potential proangiogenic factors during melanoma progression

Call: PRELUDIUM 16 , Panel: NZ4

Principal investigator: dr Magdalena Surman

Uniwersytet Jagielloński, Wydział Biologii