Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of omega-3 polyunsaturated acids supplementation on endothelial function, oxidative stress, platelet aggregation, blood coagulation and inflammation in patients with type 2 diabetes and cardiovascular disease.

2011/03/B/NZ5/05767

Keywords:

diabetes cardiovascular disease omega-3 polyunsaturated fatty acids blood coagulation platelet aggregation oxidative stress inflammation endothelium

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Grzegorz Gajos 

Number of co-investigators in the project: 6

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 604 700 PLN

Project start date (Y-m-d): 2012-07-27

Project end date (Y-m-d): 2016-10-26

Project duration:: 51 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Sprzęt komputerowy.
  2. Fluorymetr do oceny generacji trombiny (125 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Low fasting glucose is associated with enhanced thrombin generation and unfavorable fibrin clot properties in type 2 diabetic patients with high cardiovascular risk
    Authors:
    Grzegorz Gajos, Malgorzata Konieczynska, Jaroslaw Zalewski, Anetta Undas
    Academic press:
    Cardiovascular Diabetology (rok: 2015, tom: 14, strony: 44-56), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12933-015-0207-2 - link to the publication
  2. "Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or in ammation in patients with atherosclerosis and type 2 diabetes".
    Authors:
    Malgorzata Poreba, Magdalena Mostowik, Aleksander Siniarski, Renata Golebiowska‐Wiatrak, Krzysztof Piotr Malinowski, Maciej Haberka, Ewa Konduracka, Jadwiga Nessler1, Anetta Undas, Grzegorz Gajos
    Academic press:
    Cardiovascular Diabetology (rok: 2017, tom: 0,701388888888889, strony: 45302), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12933-017-0523-9 - link to the publication
  3. Treatment with omega-3 polyunsaturated fatty acids does not improve endothelial function in patients with type 2 diabetes and very high cardiovascular risk: A randomized, double-blind, placebo-controlled study (Omega-FMD)
    Authors:
    Aleksander Siniarski, Maciej Haberka, Magdalena Mostowik, Renata Gołębiowska-Wiatrak, Małgorzata Poręba, Krzysztof Piotr Malinowski, Zbigniew Gąsior, Ewa Konduracka, Jadwiga Nessler, Grzegorz Gajos
    Academic press:
    Atherosclerosis (rok: 2018, tom: 271, strony: 148-155), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.atherosclerosis.2018.02.030 - link to the publication
  4. Association of serum levels of lipoprotein A-I and lipoprotein A-I/A-II with high on-treatment platelet reactivity in patients with ST-segment elevation myocardial infarction
    Authors:
    Aleksander Siniarski, Rafał Grzybczak, Paweł Rostoff, Jarosław Zalewski, Urszula Czubek, Jadwiga Nessler, Grzegorz Gajos
    Academic press:
    The Anatolian Journal of Cardiology (rok: 2018, tom: 19, strony: 374-81), Wydawca: Turkish Society of Cardiology
    Status:
    Published
    DOI:
    10.14744/AnatolJCardiol.2018.63549 - link to the publication
  5. Diabetes and cardiovascular disease: from new mechanisms to new therapies
    Authors:
    Grzegorz Gajos
    Academic press:
    POLISH ARCHIVES OF INTERNAL MEDICINE (rok: 2018, tom: 128(3), strony: 178-186), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.4227.Epub - link to the publication
  6. Left circumflex coronary artery aneurysm with arteriovenous fistula to the coronary sinus presenting as acute coronary syndrome
    Authors:
    Siniarski A, Rostoff P, Laskowicz B, Rychlak R, Nessler J, Gajos G.
    Academic press:
    Polskie Archiwum Medycyny Wewnętrznej (rok: 2016, tom: 126, strony: 899-900), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.3658 - link to the publication
  7. Relationship between polyunsaturated fatty acid composition in serum phospholipids, systemic low-grade inflammation, and glycemic control in patients with type 2 diabetes and atherosclerotic cardiovascular disease
    Authors:
    Malgorzata Poreba, Pawel Rostoff, Aleksander Siniarski, Magdalena Mostowik, Renata Golebiowska‐Wiatrak, Jadwiga Nessler, Anetta Undas and Grzegorz Gajos
    Academic press:
    Cardiovascular Diabetology (rok: 2018, tom: 0,728472222222222, strony: 45302), Wydawca: BioMed
    Status:
    Published
    DOI:
    10.1186/s12933-018-0672-5 - link to the publication

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