Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of the interleukin 6 in aging of the cardiovascular system

2011/01/B/NZ4/04862

Keywords:

interleukin 6 aging cardiovascular system heart endothelium

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ4_2: Physiology
  • NZ4_18:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

woj. podlaskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Karol Kamiński 

Number of co-investigators in the project: 9

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 398 000 PLN

Project start date (Y-m-d): 2011-12-16

Project end date (Y-m-d): 2014-12-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Głowica liniowa (55 000 PLN)
  2. Klatki dla zwierząt pozwalające na ocenę metabolizmu (13 250 PLN)
  3. Kriostat (70 000 PLN)
  4. Oksygraf do badania metabolizmu tlenowego (19 987 PLN)
  5. Aparat do nieinwazyjnego pomiaru ciśnienia tętniczego u myszy (19 697 PLN)
  6. Cewnik z końcówką pressure-tip (13 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Interleukin 6 modulates PPARα and PGC-1α and is involved in high-fat diet induced cardiac lipotoxicity in mouse
    Authors:
    Tomasz A. Bonda, Beata Szynaka,Magdalena Sokołowska, Magdalena Dziemidowicz, EwaWaszkiewicz, Maria M. Winnicka, Piotr Bernaczyk, Natalia Wawrusiewicz-Kurylonek, Karol A. Kamiński
    Academic press:
    International Journal of Cardiology (rok: 2016, tom: 219, strony: 45299), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijcard.2016.05.021 - link to the publication
  2. Interleukin-6 and aging regulate PPARα-PGC-1α axis in the myocardium
    Authors:
    Tomasz A Bonda; Magdalena Dziemidowicz ; Magdalena Sokołowska; Szynaka Beata; Ewa Waszkiewicz; Maria M Winnicka; Karol A Kamiński
    Academic press:
    Cytokine , Wydawca: Elsevier
    Status:
    Submitted
  3. CCN1 expression in interleukin-6 deficient mouse kidney in experimental model of heart failure
    Authors:
    Tomasz Andrzej Bonda, Andrzej Taranta, Karol Adam Kaminski, Magdalena Dziemidowicz, Sergey Litvinovich, Marcin Kozuch, Izabela Bialuk, Lech Chyczewski, Maria Malgorzata Winnicka
    Academic press:
    Folia Histochemica et Cytobiologica (rok: 2013, tom: 51/1, strony: 84-91), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/FHC.2013.0012 - link to the publication
  4. Remodeling of the intercalated disc related to aging in mouse heart
    Authors:
    Tomasz A. Bonda, Beata Szynaka, Magdalena Sokołowska, Magdalena Dziemidowicz, Maria M.Winnicka, Lech Chyczewski, Karol A.Kamiński
    Academic press:
    Journal of Cardiology (rok: 2016, tom: online, strony: online), Wydawca: ELSEVIER
    Status:
    Published
  1. Age-related degenerative changes of intercalated disc affect impulse propagation in mouse ventricular myocardium.
    Authors:
    K Kaminski, TA Bonda, B Szynaka, M Dziemidowicz, M Sokolowska, WJ Musial, MM Winnicka
    Conference:
    Heart Failure Congress 2015 (rok: 2015, ), Wydawca: European Journal of Heart Failure Abstracts Supplement (2015) 17 (Supplement 1)
    Data:
    konferencja 23-26.05.2015
    Status:
    Published